New method for analyzing pharmacodynamic material basis of traditional Chinese medicines by using specific knockout technology with monoclonal antibodies

Zhongguo Zhongyao Zazhi

Volumn 38, Issue 17, 2013, Pages 2906-2910

  Zhao, Yan ^a   Qu, Hui Hua ^a   Wang, Qing Guo ^a  

^a BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Immunoaffinity chromatography; Pharmacodynamic material basis of traditional Chinese medicines; Small molecule monoclonal antibody; Specific knockout

Indexed keywords

MONOCLONAL ANTIBODY;

ARTICLE; CHINESE MEDICINE; GENE INACTIVATION; IMMUNOAFFINITY CHROMATOGRAPHY; PHARMACODYNAMICS;

ADSORPTION; ANIMALS; ANTIBODIES, MONOCLONAL; CELL LINE; CHROMATOGRAPHY, AFFINITY; DRUGS, CHINESE HERBAL; HUMANS;

EID: 84890354468     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: 10.4268/cjcmm20131733     Document Type: Article

References (28)

1. 2009, 34(2): 119.
2. 2012, 32(10): 1418.
3. Yau K Y, Lee H, Hall J C. Emerging trends in the synthesis and improvement of hapten-specific recombinant antibodies [J]. Biotech Adv, 2003, 21: 599.
4. Eremin S A, Ryabova I A, Yakovleva J N, et al. Development of a rapid, specific fluorescence polarization immunoassay for the herbicide chlorsulfuron [J]. Anal Chim Acta, 2002, 4682: 229.
5. Ueda H. Sensitive noncompetitive measurement of small molecules by open sandwich immunoassay [J]. Yakugaku Zasshi, 2007, 127: 71.
6. 2012(10): 1880.
7. 2009.
8. 2010.
9. 2010, 33(9): 606.
10. 2010.
11. 2012.
12. 2011.
13. 2011.
14. 2011.
15. 2010.
16. Zhao Y, Qu H, Zhang G, et al. Study of the metabolic characteristics of geniposide in the different encephalic region of the SD rats [J]. Neurochem Res, 2012, 37: 2272.
17. 2008, 31(1): 23.
18. 2011.
19. 2010(10): 667.
20. 2012.
21. Kido K, Edakuni K, Morinaga O, et al. An enzyme-linked immuno sorbent assay for a conitine-type alkaloids using an anti-aconitine monoclonal antibody [J]. Anal Chim Acta, 2008, 616: 109.
22. Tian Min, Tanaka H, Shang M, et al. Production, characterization of monoclonal antibody against aristolochic acid II and development of its assay system [J]. Am J Chin Med, 2008, 36: 425.
23. 1 monoclonal antibodies [J]. Biol Pharm Bull, 2001, 24: 1157.
24. Shoyama Y. New strategy for drug discovery using monoclonal antibody [J]. Curr Drug Disc Techn, 2011, 8: 1.
25. Tanaka H. Immunochemical approach using monoclonal antibody against 9-tetrahydrocannabinolic acid (THCA) to discern cannabis plants and to investigate new drug candidates [J]. Curr Drug Disc Techn, 2011, 8: 3.
26. Uto T, Tuvshintogtokh I, Shoyama Y. Preparation of knockout extract for determination of really active compound using MAb [J]. Curr Drug Disc Techn, 2011, 8: 16.
27. Putalun W. Technology of compact MAb and its application for medicinal plant breeding named as missile type molecular breeding [J]. Curr Drug Disc Techn, 2011, 8: 24.
28. Zhang L, Sun Y, Chen T, et al. Selective depletion of glycyrrhizin from Si-Ni-San, a traditional Chinese prescription, blocks its effect on contact sensitivity in mice and recovers adhesion and metalloproteinases production of T lymphocytes [J]. Int Immunopharmacol, 2005, 5: 1193.