Is CA72-4 a useful biomarker in differential diagnosis between ovarian endometrioma and epithelial ovarian cancer?

Disease Markers

Volumn 35, Issue 5, 2013, Pages 331-335

  Anastasi, Emanuela ^a   Manganaro, Lucia ^b   Granato, Teresa ^c   Panici, Pierluigi Benedetti ^d   Frati, Luigi ^a   Porpora, Maria Grazia ^d  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c CNR   (Italy)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CA 125 ANTIGEN; CA 72-4 ANTIGEN;

ADULT; AGED; ARTICLE; CANCER STAGING; COMPARATIVE STUDY; CONTROLLED STUDY; DIAGNOSTIC ERROR; DIFFERENTIAL DIAGNOSIS; DISEASE MARKER; ENDOMETRIOSIS; ENDOMETRIUM TUMOR; ENZYME IMMUNOASSAY; FEMALE; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MIDDLE AGED; OVARY CARCINOMA; PRIORITY JOURNAL; PROTEIN DETERMINATION; SERUM; YOUNG ADULT;

ADULT; AGED; ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; CA-125 ANTIGEN; CARCINOMA; DIAGNOSIS, DIFFERENTIAL; ENDOMETRIOSIS; FEMALE; HUMANS; MEMBRANE PROTEINS; MIDDLE AGED; OVARIAN NEOPLASMS;

EID: 84890333939     PISSN: 02780240     EISSN: 18758630     Source Type: Journal    
DOI: 10.1155/2013/984641     Document Type: Article

References (27)

1. B. Eskenazi and M. L. Warner, "Epidemiology of endometriosis," Obstetrics and Gynecology Clinics of North America, vol. 24, no. 2, pp. 235-258, 1997.
2. L. C. Giudice, "Endometriosis," The New England Journal of Medicine, vol. 362, no. 25, pp. 2389-2398, 2010.
3. M. G. Porpora, P. R. Koninckx, J. Piazze, M. Natili, S. Colagrande, and E. V. Cosmi, "Correlation between endometriosis and pelvic pain," Journal of the American Association of Gynecologic Laparoscopists, vol. 6, no. 4, pp. 429-434, 1999.
4. M. G. Porpora, D. Pallante,A. Ferro, B.Crisafi, F. Bellati, and P. Benedetti Panici, "Pain and ovarian endometrioma recurrence after laparoscopic treatment of endometriosis: a long-term prospective study," Fertility and Sterility, vol. 93, no. 3, pp. 716-721, 2010.
5. M. E. Coccia, F. Rizzello, A. Palagiano, and G. Scarselli, "Longterm follow-up after laparoscopic treatment for endometriosis: multivariate analysis of predictive factors for recurrence of endometriotic lesions and pain," European Journal of Obstetrics Gynecology and Reproductive Biology, vol. 157, no. 1, pp. 78-83, 2011.
6. L. J. E. W. van Dijk, W. L. D. M. Nelen, T. M. D'Hooghe et al., "The European Society of Human Reproduction and Embryology guideline for the diagnosis and treatment of endometriosis: an electronic guideline implementability appraisal," Implementation Science, vol. 6, no. 1, article 7, 2011.
7. L. Bordin, C. Fiore, G. Don et al., "Evaluation of erythrocyte band 3 phosphotyrosine level, glutathione content, CA-125, and human epididymal secretory protein E4 as combined parameters in endometriosis," Fertility and Sterility, vol. 94, no. 5, pp. 1616-1621, 2010.
8. J. M. Escudero, J. M. Auge, X. Filella, A. Torne, J. Pahisa, and R. Molina, "Comparison of serum human epididymis protein 4 with cancer antigen 125 as a tumor marker in patients with malignant and nonmalignant diseases," Clinical Chemistry, vol. 57, no. 11, pp. 1534-1544, 2011.
9. R.-H. He, W.-M. Yao, L.-Y. Wu, and Y.-Y. Mao, "Highly elevated serum CA-125 levels in patients with non-malignant gynecological diseases," Archives of Gynecology and Obstetrics, vol. 283, no. 1, pp. S107-S110, 2011.
10. M.R.McLemore, B. E. Aouizerat, K. A. Lee et al., "Acomparison of the cyclic variation in serum levels of CA125 across the menstrual cycle using two commercial assays," Biological Research For Nursing, vol. 14, no. 3, pp. 250-256, 2012.
11. S. Gupta, A. Agarwal, L. Sekhon, N. Krajcir,M. Cocuzza, and T. Falcone, "Serum and peritoneal abnormalities in endometriosis: potential use as diagnostic markers," Minerva Ginecologica, vol. 58, no. 6, pp. 527-551, 2006.
12. R. C. Bast Jr., T. L. Klug, and E. St. John, "A radioimmunoassay using amonoclonal antibody tomonitor the course of epithelial ovarian cancer,"The New England Journal of Medicine, vol. 309, no. 15, pp. 883-887, 1983.
13. I. Tsoumpou, M. Kyrgiou, T. A. Gelbaya, and L. G. Nardo, "The effect of surgical treatment for endometrioma on in vitro fertilization outcomes: a systematic review and meta-analysis," Fertility and Sterility, vol. 92, no. 1, pp. 75-87, 2009.
14. F. Raffi, M. Metwally, and S. Amer, "The impact of excision of ovarian endometrioma on ovarian reserve: a systematic review and meta-analysis," The Journal of Clinical Endocrinology & Metabolism, vol. 97, no. 9, pp. 3146-3154, 2012.
15. N. F. Vlahos,K.P.Economopoulos, andS.Fotiou, "Endometriosis, in vitro fertilisation and the risk of gynaecological malignancies, including ovarian and breast cancer," Best Practice and Research, vol. 24, no. 1, pp. 39-50, 2010.
16. D. Zygouris, V. Leontara, G. M. Makris et al., "Endometrioid ovarian cancer arising from an endometriotic cyst in a young patient," European Journal of Gynaecological Oncology, vol. 33, pp. 324-325, 2012.
17. T. Vasilakaki, E. Skafida, E. Arkoumani, X. Grammatoglou, N. Firfiris, and K. Manoloudaki, "Borderline clear cell adenofibroma of the ovary associated with ovarian endometriosis: a case report," European Journal of Gynaecological Oncology, vol. 33, pp. 230-232, 2012.
18. M. S. Lenhard, S. Nehring, D. Nagel et al., "Predictive value of CA 125 and CA 72-4 in ovarian borderline tumors," Clinical Chemistry and Laboratory Medicine, vol. 47, no. 5, pp. 537-542, 2009.
19. T. Granato, C. Midulla, F. Longo, B. Colaprisca, L. Frati, and E. Anastasi, "Role of HE4, CA72.4, and CA125 in monitoring ovarian cancer," Tumor Biology, vol. 33, no. 5, pp. 1335-1339, 2012.
20. L.Manganaro, F. Fierro, A.Tomei et al., "Beyond laparoscopy: 3-Tmagnetic resonance imaging in the evaluation of posteriorculde-sac obliteration," Magnetic Resonance Imaging, vol. 30, pp. 1432-1438, 2011.
21. L. Manganaro, F. Fierro, A. Tomei et al., "Feasibility of 3.0 T pelvic MR imaging in the evaluation of endometriosis," European Journal of Radiology, vol. 81, no. 6, pp. 1381-1387, 2011.
22. American Society for Reproductive Medicine, "Revised American Society for Reproductive Medicine classification of endometriosis," Fertility and Sterility, vol. 67, no. 5, pp. 817-821, 1997.
23. W. C. Helm, Ovarian Cancer Staging, 2011.
24. C.VanHolsbeke,B.VanCalster, S. Guerriero et al., "Endometriomas: their ultrasound characteristics," Ultrasound in Obstetrics and Gynecology, vol. 35, no. 6, pp. 730-740, 2010.
25. C. L. Pearce, C. Templeman, M. A. Rossing et al., "Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case-control studies," The Lancet Oncology, vol. 13, no. 4, pp. 385-394, 2012.
26. R. G. Moore, M. C. Miller, M. M. Steinhoff et al., "Serum HE4 levels are less frequently elevated than CA125 in women with benign gynecologic disorders," American Journal of Obstetrics and Gynecology, vol. 206, no. 4, pp. 351.e1-351.e8, 2012.
27. E. Anastasi, T. Granato, R. Falzarano et al., "The use of HE4, CA125 and CA72-4 biomarkers for differential diagnosis between ovarian endometrioma and epithelial ovarian cancer," Journal of Ovarian Research, vol. 6, pp. 1-8, 2013.