Fingerprint changes in CSF composition associated with different aetiologies in human neonatal hydrocephalus: Glial proteins associated with cell damage and loss

Fluids and Barriers of the CNS

Volumn 10, Issue 1, 2013, Pages

  Naureen, Irum ^a,e   Waheed, Khawaja A I ^b   Rathore, Ahsen W ^b   Victor, Suresh ^a   Mallucci, Conor ^c   Goodden, John R ^d   Chohan, Shahid N ^e   Miyan, Jaleel A ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b CHILDREN S HOSPITAL   (Pakistan)

^c ALDER HEY CHILDREN S HOSPITAL   (United Kingdom)

^d LEEDS GENERAL INFIRMARY   (United Kingdom)

^e COMSATS Institute of Information and Technology ^*  (Pakistan)

Author keywords

CNPase; CSF; GFAP; Human neonates; Hydrocephalus; MBP; Vimentin

Indexed keywords

2',3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; GLIAL FIBRILLARY ACIDIC PROTEIN; MYELIN BASIC PROTEIN; VIMENTIN;

ARTICLE; CELL DAMAGE; CELL LOSS; CEREBROSPINAL FLUID; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; FINGER DERMATOGLYPHICS; HUMAN; HYDROCEPHALUS; INFANT; LUMBAR PUNCTURE; MALE; NEWBORN; ONSET AGE; PRIORITY JOURNAL; SPINAL DYSRAPHISM; WESTERN BLOTTING;

EID: 84890330402     PISSN: None     EISSN: 20458118     Source Type: Journal    
DOI: 10.1186/2045-8118-10-34     Document Type: Article

References (69)

1. Zhang J, Williams MA, Rigamonti D. Genetics of human hydrocephalus. J Neurol 2006, 253:1255-1266. 10.1007/s00415-006-0245-5, 1705504, 16773266.
2. Pattisapu JV. Etiology and clinical course of hydrocephalus. Neurosurg Clin N Am 2001, 12:651-659. vii.
3. McAllister JP, Chovan P. Neonatal hydrocephalus. Mechanisms and consequences. Neurosurg Clin N Am 1998, 9:73-93.
4. McAllister JP. Pathophysiology of congenital and neonatal hydrocephalus. Semin Fetal Neonatal Med 2012, 17:285-294. 10.1016/j.siny.2012.06.004, 22800608.
5. Vachha B, Adams R. Language sample analysis in children with myelomeningocele and shunted hydrocephalus. Eur J Pediatr Surg 2003, 13(Suppl 1):S36-S37.
6. Hetherington R, Dennis M, Barnes M, Drake J, Gentili F. Functional outcome in young adults with spina bifida and hydrocephalus. Childs Nervous System 2006, 22:117-124.
7. Milhorat TH. Hydrocephalus and the Cerebrospinal Fluid 1972, Baltimore: Williams and Wilkins Co.
8. Milhorat TH, Davis DA, Hammock MK. Localization of ouabin-sensitive Na-K ATPase in frog, rabbit and rat choroid plexus. Brain Res 1975, 99:170-174. 10.1016/0006-8993(75)90622-8, 127406.
9. Cains S, Shepherd A, Nabiuni M, Owen-Lynch PJ, Miyan J. Addressing a folate imbalance in fetal cerebrospinal fluid can decrease the incidence of congenital hydrocephalus. J Neuropathol Exp Neurol 2009, 68:404-416. 10.1097/NEN.0b013e31819e64a7, 19287311.
10. Gato A, Desmond ME. Why the embryo still matters: CSF and the neuroepithelium as interdependent regulators of embryonic brain growth, morphogenesis and histiogenesis. Dev Biol 2009, 327:263-272. 10.1016/j.ydbio.2008.12.029, 19154733.
11. Lehtinen MK, Walsh CA. Neurogenesis at the brain-cerebrospinal fluid interface. Annu Rev Cell Dev Biol 2011, 27:653-679. 10.1146/annurev-cellbio-092910-154026, 3777264, 21801012.
12. Lehtinen MK, Zappaterra MW, Chen X, Yang YJ, Hill AD, Lun M, Maynard T, Gonzalez D, Kim S, Ye P, et al. The cerebrospinal fluid provides a proliferative niche for neural progenitor cells. Neuron 2011, 69:893-905. 10.1016/j.neuron.2011.01.023, 3085909, 21382550.
13. Zappaterra MW, Lehtinen MK. The cerebrospinal fluid: regulator of neurogenesis, behavior, and beyond. Cell Mol Life Sci 2012, 69:2863-2878. 10.1007/s00018-012-0957-x, 3856656, 22415326.
14. Miyan JA, Zendah M, Mashayekhi F, Owen-Lynch PJ. Cerebrospinal fluid supports viability and proliferation of cortical cells in vitro, mirroring in vivo development. Cerebrospinal Fluid Res 2006, 3:2. 10.1186/1743-8454-3-2, 1450312, 16549001.
15. Nabiuni M, Rasouli J, Parivar K, Kochesfehani HM, Irian S, Miyan JA. In vitro effects of fetal rat cerebrospinal fluid on viability and neuronal differentiation of PC12 cells. Fluids Barriers CNS 2012, 9:8. 10.1186/2045-8118-9-8, 3386012, 22494846.
16. Schutzer SE, Liu T, Natelson BH, Angel TE, Schepmoes AA, Purvine SO, Hixson KK, Lipton MS, Camp DG, Coyle PK, et al. Establishing the proteome of normal human cerebrospinal fluid. PLoS One 2010, 5:e10980. 10.1371/journal.pone.0010980, 2881861, 20552007.
17. Morales DM, Townsend RR, Malone JP, Ewersmann CA, Macy EM, Inder TE, Limbrick DD. Alterations in protein regulators of neurodevelopment in the cerebrospinal fluid of infants with posthemorrhagic hydrocephalus of prematurity. Mol Cell Proteomics 2012, 11:M111 011973. 3433889, 22186713.
18. Owen-Lynch PJ, Draper CE, Mashayekhi F, Bannister CM, Miyan JA. Defective cell cycle control underlies abnormal cortical development in the hydrocephalic Texas rat. BRAIN 2003, 126:623-631. 10.1093/brain/awg058, 12566283.
19. Mashayekhi F, Draper CE, Bannister CM, Pourghasem M, Owen-Lynch PJ, Miyan JA. Deficient cortical development in the hydrocephalic Texas (H-Tx) rat: a role for CSF. BRAIN 2002, 125:1859-1874. 10.1093/brain/awf182, 12135976.
20. Hale PM, Mcallister JP, Katz SD, Wright LC, Lovely TJ, Miller DW, Wolfson BJ, Salotto AG, Shroff DV. Improvement of cortical morphology in infantile hydrocephalic animals after ventriculoperitoneal shunt placement. Neurosurgery 1992, 31:1085-1096. 10.1227/00006123-199212000-00015, 1470319.
21. Mori K, Shimada J, Kurisaka M, Sato K, Watanabe K. Classification of hydrocephalus and outcome of treatment. Brain Dev 1995, 17:338-348. 10.1016/0387-7604(95)00070-R, 8579221.
22. Hawkins D, Bowers TM, Bannister CM, Miyan JA. The functional outcome of shunting H-Tx rat pups at different ages. Eur J Pediatr Surg 1997, 7(Suppl 1):31-34.
23. McKeating EG, Andrews PJ, Tocher JI, Menon DK. The intensive care of severe head injury: a survey of non-neurosurgical centres in the United Kingdom. Br J Neurosurg 1998, 12:7-14. 10.1080/02688699845438, 11013640.
24. Wikkelso C, Blomstrand C. Cerebrospinal fluid proteins and cells in normal-pressure hydrocephalus. J Neurol 1982, 228:171-180. 10.1007/BF00313729, 6186790.
25. Del Bigio MR. Neuropathological changes caused by hydrocephalus. Acta Neuropathol 1993, 85:573-585. 10.1007/BF00334666, 8337936.
26. Del Bigio MR, Bruni JE, Vriend JP. Monoamine neurotransmitters and their metabolites in the mature rabbit brain following induction of hydrocephalus. Neurochem Res 1998, 23:1379-1386. 10.1023/A:1020798622692, 9814548.
27. Del Bigio MR, da Silva MC, Drake JM, Tuor UI. Acute and chronic cerebral white matter damage in neonatal hydrocephalus. Can J Neurol Sci 1994, 21:299-305.
28. Harris NG, Jones HC, Patel S. Ventricle shunting in young H-Tx rats with inherited congenital hydrocephalus: a quantitative histological study of cortical grey matter. Childs Nerv Syst 1994, 10:293-301. discussion 301, 10.1007/BF00335166, 7954498.
29. Kondziella D, Qu H, Ludemann W, Brinker T, Sletvold O, Sonnewald U. Astrocyte metabolism is disturbed in the early development of experimental hydrocephalus. J Neurochem 2003, 85:274-281. 10.1046/j.1471-4159.2003.01656.x, 12641749.
30. Murray K, Noble M. In vitro studies on the comparative sensitivities of cells of the central nervous system to diphtheria toxin. J Neurol Sci 1985, 70:283-293. 10.1016/0022-510X(85)90170-4, 4056824.
31. Khan OH, Enno TL, Del Bigio MR. Brain damage in neonatal rats following kaolin induction of hydrocephalus. Exp Neurol 2006, 200:311-320. 10.1016/j.expneurol.2006.02.113, 16624304.
32. Del Bigio MR, Zhang YW. Cell death, axonal damage, and cell birth in the immature rat brain following induction of hydrocephalus. Exp Neurol 1998, 154:157-169. 10.1006/exnr.1998.6922, 9875277.
33. Ding YX, Wei LC, Liu YH, Duan L, Jiao XY, Xia Y, Chen LW. Midbrain neural stem cells show unique cell survival, neuronal commitment and neurotrophic properties with therapeutic potential for parkinson's disease. J Alzheimers Dis Res 2012, S10:001. doi:10.4172/2161-0460.
34. Stephenson DT, O'Neill SM, Narayan S, Tiwari A, Arnold E, Samaroo HD, Du F, Ring RH, Campbell B, Pletcher M, et al. Histopathologic characterization of the BTBR mouse model of autistic-like behavior reveals selective changes in neurodevelopmental proteins and adult hippocampal neurogenesis. Mol Autism 2011, 2:7. 10.1186/2040-2392-2-7, 3135520, 21575186.
35. Nabiuni M. Analysis of protein content of cerebrospinal fluid in developing hydrocephalic texas rat 2006, The University of Manchester, Faculty of Life Sciences, PhD Thesis.
36. Miyan JA, Khan MI, Kawarada Y, Sugiyama T, Bannister CM. Cell death in the brain of the HTx rat. Eur J Pediatr Surg 1998, 8(Suppl 1):43-48.
37. Bartosik-Psujek H, Stelmasiak Z. Biochemical markers of damage of the central nervous system in multiple sclerosis. Ann Univ Mariae Curie Sklodowska Med 2001, 56:389-392.
38. Malmestrom C, Haghighi S, Rosengren L, Andersen O, Lycke J. Neurofilament light protein and glial fibrillary acidic protein as biological markers in MS. Neurology 2003, 61:1720-1725. 10.1212/01.WNL.0000098880.19793.B6, 14694036.
39. Roessmann U, Velasco ME, Sindely SD, Gambetti P. Glial fibrillary acidic protein (GFAP) in ependymal cells during development. An immunocytochemical study. Brain Res 1980, 200:13-21. 10.1016/0006-8993(80)91090-2, 6998542.
40. Albrechtsen M, Sorensen PS, Gjerris F, Bock E. High cerebrospinal fluid concentration of glial fibrillary acidic protein (GFAP) in patients with normal pressure hydrocephalus. J Neurol Sci 1985, 70:269-274. 10.1016/0022-510X(85)90168-6, 4056822.
41. Tullberg M, Rosengren L, Blomsterwall E, Karlsson JE, Wikkelso C. CSF neurofilament and glial fibrillary acidic protein in normal pressure hydrocephalus. Neurology 1998, 50:1122-1127. 10.1212/WNL.50.4.1122, 9566405.
42. Miller JM, McAllister JP. Reduction of astrogliosis and microgliosis by cerebrospinal fluid shunting in experimental hydrocephalus. Cerebrospinal Fluid Res 2007, 4:5. 10.1186/1743-8454-4-5, 1899521, 17555588.
43. Del Bigio MR, Kanfer JN, Zhang YW. Myelination delay in the cerebral white matter of immature rats with kaolin-induced hydrocephalus is reversible. J Neuropathol Exp Neurol 1997, 56:1053-1066. 10.1097/00005072-199709000-00010, 9291946.
44. Eskandari R, Harris CA, McAllister JP. Reactive astrocytosis in feline neonatal hydrocephalus: acute, chronic, and shunt-induced changes. Childs Nerv Syst 2011, 27:2067-2076. 10.1007/s00381-011-1552-4, 21847645.
45. Levin SD, Hoyle NR, Brown JK, Thomas DG. Cerebrospinal fluid myelin basic protein immunoreactivity as an indicator of brain damage in children. Dev Med Child Neurol 1985, 27:807-813.
46. Miller A, Glass-Marmor L, Abraham M, Grossman I, Shapiro S, Galboiz Y. Bio-markers of disease activity and response to therapy in multiple sclerosis. Clin Neurol Neurosurg 2004, 106:249-254. 10.1016/j.clineuro.2004.02.008, 15177778.
47. Yung YC, Mutoh T, Lin ME, Noguchi K, Rivera RR, Choi JW, Kingsbury MA, Chun J. Lysophosphatidic acid signaling may initiate fetal hydrocephalus. Sci Transl Med 2011, 3:99ra87. 3653407, 21900594.
48. Sutton LN, Wood JH, Brooks BR, Barrer SJ, Kline M, Cohen SR. Cerebrospinal fluid myelin basic protein in hydrocephalus. J Neurosurg 1983, 59:467-470. 10.3171/jns.1983.59.3.0467, 6193255.
49. Hanlo PW, Gooskens RJ, van Schooneveld M, Tulleken CA, van der Knaap MS, Faber JA, Willemse J. The effect of intracranial pressure on myelination and the relationship with neurodevelopment in infantile hydrocephalus. Dev Med Child Neurol 1997, 39:286-291.
50. Franke WW, Schmid E, Osborn M, Weber K. Different intermediate-sized filaments distinguished by immunofluorescence microscopy. Proc Natl Acad Sci U S A 1978, 75:5034-5038. 10.1073/pnas.75.10.5034, 336257, 368806.
51. Kamei Y, Inagaki N, Nishizawa M, Tsutsumi O, Taketani Y, Inagaki M. Visualization of mitotic radial glial lineage cells in the developing rat brain by Cdc2 kinase-phosphorylated vimentin. Glia 1998, 23:191-199. 10.1002/(SICI)1098-1136(199807)23:3<191::AID-GLIA2>3.0.CO;2-8, 9633804.
52. Kalman M, Szekely AD, Csillag A. Distribution of glial fibrillary acidic protein and vimentin-immunopositive elements in the developing chicken brain from hatch to adulthood. Anat Embryol (Berl) 1998, 198:213-235. 10.1007/s004290050179, 9764976.
53. Sancho-Tello M, Valles S, Montoliu C, Renau-Piqueras J, Guerri C. Developmental pattern of GFAP and vimentin gene expression in rat brain and in radial glial cultures. Glia 1995, 15:157-166. 10.1002/glia.440150208, 8567067.
54. Mucke L, Eddleston M. Astrocytes in infectious and immune-mediated diseases of the central nervous system. FASEB J 1993, 7:1226-1232.
55. Eddleston M, de la Torre JC, Oldstone MB, Loskutoff DJ, Edgington TS, Mackman N. Astrocytes are the primary source of tissue factor in the murine central nervous system. A role for astrocytes in cerebral hemostasis. J Clin Invest 1993, 92:349-358. 10.1172/JCI116573, 293611, 8326003.
56. Eddleston M, Mucke L. Molecular profile of reactive astrocytes-implications for their role in neurologic disease. Neuroscience 1993, 54:15-36. 10.1016/0306-4522(93)90380-X, 8515840.
57. Graeber MB, Streit WJ, Kreutzberg GW. The microglial cytoskeleton: vimentin is localized within activated cells in situ. J Neurocytol 1988, 17:573-580. 10.1007/BF01189811, 3193132.
58. Takano T, Rutka JT, Becker LE. Overexpression of nestin and vimentin in ependymal cells in hydrocephalus. Acta Neuropathol 1996, 92:90-97. 10.1007/s004010050493, 8811130.
59. Reinikainen KJ, Pitkanen A, Riekkinen PJ. 2′,3′-cyclic nucleotide-3′-phosphodiesterase activity as an index of myelin in the post-mortem brains of patients with Alzheimer's disease. Neurosci Lett 1989, 106:229-232. 10.1016/0304-3940(89)90230-9, 2555748.
60. Vogel US, Thompson RJ. Molecular structure, localization, and possible functions of the myelin-associated enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase. J Neurochem 1988, 50:1667-1677. 10.1111/j.1471-4159.1988.tb02461.x, 2836557.
61. Braun PE, Sandillon F, Edwards A, Matthieu JM, Privat A. Immunocytochemical localization by electron microscopy of 2′3′-cyclic nucleotide 3′-phosphodiesterase in developing oligodendrocytes of normal and mutant brain. J Neurosci 1988, 8:3057-3066.
62. Trapp BD, Bernier L, Andrews SB, Colman DR. Cellular and subcellular distribution of 2′,3′-cyclic nucleotide 3′-phosphodiesterase and its mRNA in the rat central nervous system. J Neurochem 1988, 51:859-868. 10.1111/j.1471-4159.1988.tb01822.x, 2842456.
63. Wu CY, Lu J, Cao Q, Guo CH, Gao Q, Ling EA. Expression of 2′,3′-cyclic nucleotide 3′-phosphodiesterase in the amoeboid microglial cells in the developing rat brain. Neuroscience 2006, 142:333-341. 10.1016/j.neuroscience.2006.06.030, 16876328.
64. Lappe-Siefke C, Goebbels S, Gravel M, Nicksch E, Lee J, Braun PE, Griffiths IR, Nave KA. Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination. Nat Genet 2003, 33:366-374. 10.1038/ng1095, 12590258.
65. Hakak Y, Walker JR, Li C, Wong WH, Davis KL, Buxbaum JD, Haroutunian V, Fienberg AA. Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia. Proc Natl Acad Sci U S A 2001, 98:4746-4751. 10.1073/pnas.081071198, 31905, 11296301.
66. Olopade FE, Shokunbi MT, Siren AL. The relationship between ventricular dilatation, neuropathological and neurobehavioural changes in hydrocephalic rats. Fluids Barriers CNS 2012, 9:19. 10.1186/2045-8118-9-19, 3464139, 22938200.
67. Yin X, Peterson J, Gravel M, Braun PE, Trapp BD. CNP overexpression induces aberrant oligodendrocyte membranes and inhibits MBP accumulation and myelin compaction. J Neurosci Res 1997, 50:238-247. 10.1002/(SICI)1097-4547(19971015)50:2<238::AID-JNR12>3.0.CO;2-4, 9373033.
68. Talab R, Valis M, Rehak S, Krejsek J. Abnormalities of tau-protein and beta-amyloid in brain ventricle cerebrospinal fluid. Neuro Endocrinol Lett 2009, 30:647-651.
69. Moghekar A, Goh J, Li M, Albert M, O'Brien RJ. Cerebrospinal fluid Abeta and tau level fluctuation in an older clinical cohort. Arch Neurol 2012, 69:246-250. 10.1001/archneurol.2011.732, 3310240, 22332192.