Enhanced trimethylation of histone H3 mediates impaired expression of hepatic glucose 6-phosphatase expression in offspring from rat dams exposed to hypoxia during pregnancy

Reproductive Sciences

Volumn 21, Issue 1, 2014, Pages 112-121

  Osumek, Jessica E ^a,b,c   Revesz, Andrew ^a,b,c   Morton, Jude S ^d   Davidge, Sandra T ^d   Hardy, Daniel B ^a,b,c  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b CHILDREN S HEALTH RESEARCH INSTITUTE   (Canada)

^c LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

^d UNIVERSITY OF ALBERTA   (Canada)

Author keywords

fetal programming; glucose 6 phosphatase; hypoxia; liver; posttranslational histone modifications

Indexed keywords

GLUCOSE 6 PHOSPHATASE; HISTONE H3; MESSENGER RNA; OXYGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GLUCONEOGENESIS; HEPATOMA CELL; HISTONE MODIFICATION; HUMAN; HUMAN CELL; HYPOXIA; INTRAUTERINE GROWTH RETARDATION; MARE; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

FETAL PROGRAMMING; GLUCOSE 6-PHOSPHATASE; HYPOXIA; LIVER; POSTTRANSLATIONAL HISTONE MODIFICATIONS;

ANIMALS; ANOXIA; BLOOD GLUCOSE; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; FEMALE; FETAL GROWTH RETARDATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GESTATIONAL AGE; GLUCOSE-6-PHOSPHATASE; HISTONES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER; MALE; METHYLATION; OXYGEN; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TIME FACTORS;

EID: 84890297357     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719113492212     Document Type: Article

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