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Volumn 4, Issue NOV, 2013, Pages

Targeting thyroid cancer microenvironment: Basic research and clinical applications

Author keywords

Biomarkers; BRAFV600E; Extracellular matrix; Microenvironment; Mouse models; Targeted therapy; Thyroid cancer; Translational

Indexed keywords

B RAF KINASE; B RAF KINASE INHIBITOR; BIOLOGICAL MARKER; INTEGRIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN P53; PROTEIN PATCHED; PROTEIN RET; RADIOACTIVE IODINE; THROMBOSPONDIN 1; TRANSCRIPTION FACTOR PAX8;

EID: 84890254497     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2013.00167     Document Type: Editorial
Times cited : (10)

References (14)
  • 1
    • 84875541817 scopus 로고    scopus 로고
    • Increasing incidence of thyroid cancer: controversies explored
    • doi: 10.1038/nrendo.2012.257
    • Ito Y, Nikiforov YE, Schlumberger M, Vigneri R. Increasing incidence of thyroid cancer: controversies explored. Nat Rev Endocrinol (2013) 9(3):178-84. doi: 10.1038/nrendo.2012.257
    • (2013) Nat Rev Endocrinol , vol.9 , Issue.3 , pp. 178-184
    • Ito, Y.1    Nikiforov, Y.E.2    Schlumberger, M.3    Vigneri, R.4
  • 2
    • 84875295216 scopus 로고    scopus 로고
    • Progress in molecular-based management of differentiated thyroid cancer
    • doi:10.1016/S0140-6736(13)60109-9
    • Xing M, Haugen BR, Schlumberger M. Progress in molecular-based management of differentiated thyroid cancer. Lancet (2013) 381(9871):1058-69. doi:10.1016/S0140-6736(13)60109-9
    • (2013) Lancet , vol.381 , Issue.9871 , pp. 1058-1069
    • Xing, M.1    Haugen, B.R.2    Schlumberger, M.3
  • 3
    • 84875952085 scopus 로고    scopus 로고
    • Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer
    • doi:10.1001/jama.2013.3190
    • Xing M, Alzahrani AS, Carson KA, Viola D, Elisei R, Bendlova B, et al. Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer. JAMA (2013) 309(14):1493-501. doi:10.1001/jama.2013.3190
    • (2013) JAMA , vol.309 , Issue.14 , pp. 1493-1501
    • Xing, M.1    Alzahrani, A.S.2    Carson, K.A.3    Viola, D.4    Elisei, R.5    Bendlova, B.6
  • 4
    • 84870798372 scopus 로고    scopus 로고
    • Clinical outcome, role of BRAF(V600E), and molecular pathways in papillary thyroid microcarcinoma: is it an indolent cancer or an early stage of papillary thyroid cancer?
    • doi:10.3389/fendo.2012.00033
    • Nucera C, Pontecorvi A. Clinical outcome, role of BRAF(V600E), and molecular pathways in papillary thyroid microcarcinoma: is it an indolent cancer or an early stage of papillary thyroid cancer? Front Endocrinol (2012) 3:33. doi:10.3389/fendo.2012.00033
    • (2012) Front Endocrinol , vol.3 , pp. 33
    • Nucera, C.1    Pontecorvi, A.2
  • 5
    • 84859551973 scopus 로고    scopus 로고
    • A combined molecular-pathologic score improves risk stratification of thyroid papillary microcarcinoma
    • doi:10.1002/cncr.26425
    • Niemeier LA, Kuffner Akatsu H, Song C, Carty SE, Hodak SP, Yip L, et al. A combined molecular-pathologic score improves risk stratification of thyroid papillary microcarcinoma. Cancer (2012) 118(8):2069-77. doi:10.1002/cncr.26425
    • (2012) Cancer , vol.118 , Issue.8 , pp. 2069-2077
    • Niemeier, L.A.1    Kuffner Akatsu, H.2    Song, C.3    Carty, S.E.4    Hodak, S.P.5    Yip, L.6
  • 6
    • 84863594882 scopus 로고    scopus 로고
    • Role of ultrasonographic/clinical profile, cytology, and BRAF V600E mutation evaluation in thyroid nodule screening for malignancy: a prospective study
    • doi:10.1210/jc.2011-3494
    • Rossi M, Buratto M, Bruni S, Filieri C, Tagliati F, Trasforini G, et al. Role of ultrasonographic/clinical profile, cytology, and BRAF V600E mutation evaluation in thyroid nodule screening for malignancy: a prospective study. J Clin Endocrinol Metab (2012) 97(7):2354-61. doi:10.1210/jc.2011-3494
    • (2012) J Clin Endocrinol Metab , vol.97 , Issue.7 , pp. 2354-2361
    • Rossi, M.1    Buratto, M.2    Bruni, S.3    Filieri, C.4    Tagliati, F.5    Trasforini, G.6
  • 7
    • 77955452828 scopus 로고    scopus 로고
    • Surgical implications of B-RafV600E mutation in fine-needle aspiration of thyroid nodules
    • doi:10.1016/j.amjsurg.2009.08.029
    • Mekel M, Nucera C, Hodin RA, Parangi S. Surgical implications of B-RafV600E mutation in fine-needle aspiration of thyroid nodules. Am J Surg (2010) 200(1):136-43. doi:10.1016/j.amjsurg.2009.08.029
    • (2010) Am J Surg , vol.200 , Issue.1 , pp. 136-143
    • Mekel, M.1    Nucera, C.2    Hodin, R.A.3    Parangi, S.4
  • 8
    • 84055191090 scopus 로고    scopus 로고
    • Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation
    • doi:10.1172/JCI46382
    • Chakravarty D, Santos E, Ryder M, Knauf JA, Liao XH, West BL, et al. Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation. J Clin Invest (2011) 121(12):4700-11. doi:10.1172/JCI46382
    • (2011) J Clin Invest , vol.121 , Issue.12 , pp. 4700-4711
    • Chakravarty, D.1    Santos, E.2    Ryder, M.3    Knauf, J.A.4    Liao, X.H.5    West, B.L.6
  • 9
    • 77953766335 scopus 로고    scopus 로고
    • B-Raf(V600E) and thrombospondin-1 promote thyroid cancer progression
    • doi:10.1073/pnas.1004934107
    • Nucera C, Porrello A, Antonello ZA, Mekel M, Nehs MA, Giordano TJ, et al. B-Raf(V600E) and thrombospondin-1 promote thyroid cancer progression. Proc Natl Acad Sci USA (2010) 107(23):10649-54. doi:10.1073/pnas.1004934107
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.23 , pp. 10649-10654
    • Nucera, C.1    Porrello, A.2    Antonello, Z.A.3    Mekel, M.4    Nehs, M.A.5    Giordano, T.J.6
  • 10
    • 79953021811 scopus 로고    scopus 로고
    • Targeting BRAFV600E with PLX4720 displays potent antimigratory and anti-invasive activity in preclinical models of human thyroid cancer
    • doi:10.1634/theoncologist.2010-0317
    • Nucera C, Nehs MA, Nagarkatti SS, Sadow PM, Mekel M, Fischer AH, et al. Targeting BRAFV600E with PLX4720 displays potent antimigratory and anti-invasive activity in preclinical models of human thyroid cancer. Oncologist (2011) 16(3):296-309. doi:10.1634/theoncologist.2010-0317
    • (2011) Oncologist , vol.16 , Issue.3 , pp. 296-309
    • Nucera, C.1    Nehs, M.A.2    Nagarkatti, S.S.3    Sadow, P.M.4    Mekel, M.5    Fischer, A.H.6
  • 11
    • 84877631604 scopus 로고    scopus 로고
    • Relief of feedback inhibition of HER3 transcription by RAF and MEK inhibitors attenuates their antitumor effects in BRAF-mutant thyroid carcinomas
    • doi:10.1158/2159-8290.CD-12-0531
    • Montero-Conde C, Ruiz-Llorente S, Dominguez JM, Knauf JA, Viale A, Sherman EJ, et al. Relief of feedback inhibition of HER3 transcription by RAF and MEK inhibitors attenuates their antitumor effects in BRAF-mutant thyroid carcinomas. Cancer Discov (2013) 3(5):520-33. doi:10.1158/2159-8290.CD-12-0531
    • (2013) Cancer Discov , vol.3 , Issue.5 , pp. 520-533
    • Montero-Conde, C.1    Ruiz-Llorente, S.2    Dominguez, J.M.3    Knauf, J.A.4    Viale, A.5    Sherman, E.J.6
  • 12
    • 77952778924 scopus 로고    scopus 로고
    • Tumor-associated lymphocytes and increased FoxP3+ regulatory T cell frequency correlate with more aggressive papillary thyroid cancer
    • doi:10.1210/jc.2009-2564
    • French JD, Weber ZJ, Fretwell DL, Said S, Klopper JP, Haugen BR. Tumor-associated lymphocytes and increased FoxP3+ regulatory T cell frequency correlate with more aggressive papillary thyroid cancer. J Clin Endocrinol Metab (2010) 95(5):2325-33. doi:10.1210/jc.2009-2564
    • (2010) J Clin Endocrinol Metab , vol.95 , Issue.5 , pp. 2325-2333
    • French, J.D.1    Weber, Z.J.2    Fretwell, D.L.3    Said, S.4    Klopper, J.P.5    Haugen, B.R.6
  • 13
    • 84861968322 scopus 로고    scopus 로고
    • Programmed death-1+ T cells and regulatory T cells are enriched in tumor-involved lymph nodes and associated with aggressive features in papillary thyroid cancer
    • doi:10.1210/jc.2011-3428
    • French JD, Kotnis GR, Said S, Raeburn CD, McIntyre RC Jr, Klopper JP, et al. Programmed death-1+ T cells and regulatory T cells are enriched in tumor-involved lymph nodes and associated with aggressive features in papillary thyroid cancer. J Clin Endocrinol Metab (2012) 97(6):E934-43. doi:10.1210/jc.2011-3428
    • (2012) J Clin Endocrinol Metab , vol.97 , Issue.6
    • French, J.D.1    Kotnis, G.R.2    Said, S.3    Raeburn, C.D.4    McIntyre Jr., R.C.5    Klopper, J.P.6
  • 14
    • 56649101166 scopus 로고    scopus 로고
    • Increased density of tumor-associated macrophages is associated with decreased survival in advanced thyroid cancer
    • doi:10.1677/ERC-08-0036
    • Ryder M, Ghossein RA, Ricarte-Filho JC, Knauf JA, Fagin JA. Increased density of tumor-associated macrophages is associated with decreased survival in advanced thyroid cancer. Endocr Relat Cancer (2008) 15(4):1069-74. doi:10.1677/ERC-08-0036
    • (2008) Endocr Relat Cancer , vol.15 , Issue.4 , pp. 1069-1074
    • Ryder, M.1    Ghossein, R.A.2    Ricarte-Filho, J.C.3    Knauf, J.A.4    Fagin, J.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.