Search for varicella zoster virus DNA in saliva of healthy individuals aged 20-59 years

Journal of Medical Virology

Volumn 86, Issue 2, 2014, Pages 360-362

  Birlea, Marius ^a   Cohrs, Randall J ^a   Bos, Nathan ^a   Mehta, Satish K ^b   Pierson, Duane L ^c   Gilden, Don ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b Enterprise Advisory Services Inc   (United States)

^c NASA JOHNSON SPACE CENTER   (United States)

Author keywords

Diagnosis; PCR; Saliva; VZV

Indexed keywords

IMMUNOGLOBULIN M ANTIBODY; VIRUS DNA;

ADULT; ARTICLE; DIAGNOSTIC VALUE; FEMALE; HUMAN; MALE; NEUROLOGIC DISEASE; NONHUMAN; NORMAL HUMAN; REAL TIME POLYMERASE CHAIN REACTION; SALIVA; SALIVA ANALYSIS; VARICELLA ZOSTER VIRUS; VIRUS DETECTION; VIRUS REACTIVATION;

HUMAN HERPESVIRUS 3;

DIAGNOSIS; PCR; SALIVA; VZV;

ADULT; DNA, VIRAL; FEMALE; HEALTHY VOLUNTEERS; HERPESVIRUS 3, HUMAN; HUMANS; MALE; MIDDLE AGED; REAL-TIME POLYMERASE CHAIN REACTION; SALIVA; SPECIMEN HANDLING; YOUNG ADULT;

EID: 84890234858     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.23834     Document Type: Article

References (16)

1. Cohrs RJ, Mehta SK, Schmid DS, Gilden DH, Pierson DL. 2008. Asymptomatic reactivation and shed of infectious varicella zoster virus in astronauts. J Med Virol 80:1116-1122.
2. Furuta Y, Ohtani F, Fukuda S, Inuyama Y, Nagashima K. 2000. Reactivation of varicella-zoster virus in delayed facial palsy after dental treatment and oro-facial surgery. J Med Virol 62:42-45.
3. Furuta Y, Ohtani F, Sawa H, Fukuda S, Inuyama Y. 2001. Quantitation of varicella-zoster virus DNA in patients with Ramsay Hunt syndrome and zoster sine herpete. J Clin Microbiol 39:2856-2859.
4. Furuta Y, Ohtani F, Aizawa H, Fukuda S, Kawabata H, Bergström T. 2005. Varicella-zoster virus reactivation is an important cause of acute facial paralysis in children. Pediatr Infect Dis J 24:97-101.
5. Gershon A. 2011. The history and mystery of VZV in saliva. J Infect Dis 204:815-816.
6. Gilden DH, Vafai A, Shtram Y, Becker Y, Devlin M, Wellish M. 1983. Varicella zoster virus DNA in human sensory ganglia. Nature 306:478-480.
7. Gilden D, Cohrs RJ, Mahalingam R, Nagel MA. 2010. Neurological disease produced by VZV reactivation without rash. Curr Top Microbiol Immunol 342:243-253.
8. Kennedy PG, Grinfeld E, Gow JW. 1998. Latent varicella-zoster virus is located predominantly in neurons in human trigeminal ganglia. Proc Natl Acad Sci USA 95:4658-4662.
9. Kennedy PG, Grinfeld E, Gow JW. 1999. Latent varicella-zoster virus in human dorsal root ganglia. Virology 258:451-454.
10. Mehta SK, Cohrs RJ, Forghani B, Zerbe G, Gilden DH, Pierson DL. 2004. Stress-induced subclinical reactivation of varicella zoster virus in astronauts. J Med Virol 72:174-179.
11. Mehta SK, Tyring SK, Gilden DH, Cohrs RJ, Leal MJ, Castro VA, Feiveson AH, Ott CM, Pierson DL. 2008. Varicella zoster virus in the saliva of patients with herpes zoster. J Infect Dis 197:654-657.
12. Nagel MA, Choe A, Cohrs RJ, Traktinskiy I, Sorensen K, Mehta SK, Pierson DL, Tyring SK, Haitz K, Digiorgio C, Lapolla W, Gilden D. 2011. Persistence of VZV DNA in saliva after herpes zoster. J Infect Dis 204:820-824.
13. Papaevangelou V, Quinlivan M, Lockwood J, Papaloukas O, Sideri G, Critselis E, Papassotiriou I, Papadatos J, Breuer J. 2013. Subclinical VZV reactivation in immunocompetent children hospitalized in the ICU associated with prolonged fever duration. Clin Microbiol Infect 19:E245-E251.
14. Pierson DL, Mehta SK, Gilden D, Cohrs RJ, Nagel MA, Schmid DS, Tyring SK. 2011. Varicella zoster virus DNA at inoculation sites and in saliva after Zostavax immunization. J Infect Dis 203:1542-1545.
15. Uchakin PN, Parish DC, Dane FC, Uchakina ON, Scheetz AP, Agarwal NK, Smith BE. 2011. Fatigue in medical residents leads to reactivation of herpes virus latency. Interdiscip Perspect Infect Dis 2011:571340.
16. Wang CC, Yepes LC, Danaher RJ, Berger JR, Mootoor Y, Kryscio RJ, Miller CS. 2010. Low prevalence of varicella zoster virus and herpes simplex virus type 2 in saliva from human immunodeficiency virus-infected persons in the era of highly active antiretroviral therapy. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109:232-237.