Dengue Epidemiology and Burden of Disease in Latin America and the Caribbean: A Systematic Review of the Literature and Meta-Analysis

Value in Health Regional Issues

Volumn 2, Issue 3, 2013, Pages 347-356

  Cafferata, María Luisa ^a   Bardach, Ariel ^a   Rey Ares, Lucila ^a   Alcaraz, Andrea ^a   Cormick, Gabriela ^a   Gibbons, Luz ^a   Romano, Marina ^a   Cesaroni, Silvana ^a   Ruvinsky, Silvina ^b  

^a INSTITUTE FOR CLINICAL EFFECTIVENESS AND HEALTH POLICY   (Argentina)

^b National Pediatric Hospital Dr J P Garrahan   (Argentina)

Author keywords

Dengue; Disease burden; Disease costs; Epidemiology; Latin America; Resource use

Indexed keywords

ARTICLE; CENTRAL AMERICA; COST OF ILLNESS; DENGUE; DISEASE DURATION; FATALITY; HEALTH CARE COST; HEALTH CARE UTILIZATION; HUMAN; INFECTION CONTROL; LENGTH OF STAY; PRIORITY JOURNAL; SYSTEMATIC REVIEW; VIRUS TRANSMISSION;

EID: 84890213182     PISSN: 22121099     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vhri.2013.10.002     Document Type: Article

References (65)

1. World Health Organization Special Programme for Research and Training in Tropical Diseases. Scientific Working Group Meeting on Dengue. Geneva: World Health Organization Special Programme for Research and Training in Tropical Diseases, 2006.
2. Tapia-Conyer R., Betancourt-Cravioto M., Mendez-Galvan J. Dengue: an escalating public health problem in Latin America. Paediatr Int Child Health 2012, 32(Suppl. 1):14-17.
3. Suaya JA, Shepard DS, Beatty ME. Dengue: Burden of Disease and Costs of Illness. Scientific Working Group Report on Dengue, 1-5 October 2006. Geneva: World Health Organization Special Programme for Research and Training in Tropical Diseases, 2006.
4. Gubler D.J. Dengue Hemorrhagic Fever: Its History and Resurgence as a Global Health Problem 1997, CAB International, Willingford, UK.
5. Gubler D.J., Clark G.G. Dengue/dengue hemorrhagic fever: the emergence of a global health problem. Emerg Infect Dis 1995, 1:55-57.
6. Gubler D.J. Aedes aegypti and Aedes aegypti-borne disease control in the 1990s: top down or bottom up. Charles Franklin Craig Lecture. Am J Trop Med Hyg 1989, 40:571-578.
7. Plan continental de ampliación e intensificación del combate al Aedes aegypti: Informe de un grupo de trabajo 1997, PAHO, Organización Panamericana de la Salud, Caracas.
8. Isturiz R.E., Gubler D.J., Brea del Castillo J. Dengue and dengue hemorrhagic fever in Latin America and the Caribbean. Infect Dis Clin North Am 2000, 14:121-140.
9. San Martin J.L., Brathwaite O., Zambrano B., et al. The epidemiology of dengue in the Americas over the last three decades: a worrisome reality. Am J Trop Med Hyg 2010, 82:128-135.
10. Coudeville L, Shepard D, Zambrano B, et al. An estimate of the dengue economic burden in the Americas. Poster (#442) presented at 58th ASTMH Annual Meeting, November 18-22, 2009, Washington, DC.
11. Shepard D.S., Coudeville L., Halasa Y.A., et al. Economic impact of dengue illness in the Americas. Am J Trop Med Hyg 2011, 84:200-207.
12. Pan American Health Organization Epidemiological Bulletin No. 2 2000, Pan American Health Organization, Washington, DC.
13. von Elm E., Altman D.G., Egger M., et al. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Lancet 2007, 370:1453-1457.
14. Sanderson S., Tatt I.D., Higgins J.P.T. Tools for assessing quality and susceptibility to bias in observational studies in epidemiology: a systematic review and annotated bibliography. Int J Epidemiol 2007, 36:666-676.
15. Fowkes FG, Fulton PM. Critical appraisal of published research: introductory guidelines. BMJ 199;302:1136-40.
16. Salgado D.M., Panqueba C.A., Vega M.R., et al. Mortalidad de dengue hemorrágico en niños en Colombia: más allá del choque. Infectio 2008, 12:249-255.
17. Rigau-Perez J.G., Ayala-Lopez A., Vorndam A.V., et al. Dengue activity in Puerto Rico during an interepidemic period (1995-1997). Am J Trop Med Hyg 2001, 64:75-83.
18. Rigau-Perez J.G., Vorndam A.V., Clark G.G. The dengue and dengue hemorrhagic fever epidemic in Puerto Rico, 1994-1995. Am J Trop Med Hyg 2001, 64:67-74.
19. Ocazionez R.E., Cortes F.M., Villar L.A., et al. Temporal distribution of dengue virus serotypes in Colombian endemic area and dengue incidence. Re-introduction of dengue-3 associated to mild febrile illness and primary infection. Memorias do Instituto Oswaldo Cruz 2006, 101:725-731.
20. Lyerla R., Rigau-Perez J.G., Vorndam A.V., et al. A dengue outbreak among camp participants in a Caribbean Island, 1995. J Trav Med 2000, 7:59-63.
21. Harris E., Videa E., Perez L., et al. Clinical, epidemiologic, and virologic features of dengue in the 1998 epidemic in Nicaragua. Am J Trop Med Hyg 2000, 63:5-11.
22. Guzmán M.G., García G., Kourí G. El dengue y el dengue hemorrágico: prioridades de investigación. Rev Panam Salud Pública 2006, 19:204-215.
23. Escobar-Mesa J., Gomez-Dantes H. Dengue fever transmission in Veracruz, Mexico: an ecological approach to disease control. Salud Publica de Mexico 2003, 45:43-53.
24. Chuit R. El dengue, una realidad hoy. Bol Acad Nac Med BAires 2000, 78:135-141.
25. Añez G., Balza R., Valero N., et al. Impacto económico del dengue y del dengue hemorrágico en el Estado de Zulia, Venezuela, 1997-2003. Rev Panam Salud Pública 2006, 19:314-320.
26. Chadee D.D. Observations on the seasonal prevalence and vertical distribution patterns of oviposition by Aedes aegypti (L.) (Diptera: Culicidae) in urban high-rise apartments in Trinidad, West Indies. J Vector Ecol 2004, 29:323-330.
27. Ministerio de Salud, ed. Centro Nacional de Diagnóstico y R. Un estudio de cohorte pediátrico de dengue en Nicaragua: procedimiento del Laboratorio de Virología, Centro de Diagnóstico y Referencia. Managua, Nicaragua: CNDR, 2004.
28. Organización Panamericana de la S, ed. In Reunión Sub-regional sobre la Promoción de Estrategias de Participacion Comunitaria y la Educación Popular en el Control del Dengue a través de la Comunicación Social: países de Centroamérica, Panamá, Belice, México y la República Dominicana. Washington, DC: Organización Panamericana de la Salud, 2000.
29. Avila Montes GA, Araujo R, Orellana Herrera G. Epidemiological situation of dengue in Honduras during the 1991-2010 period. Rev Med Hondur 2010;78.
30. Stroup D.F., Berlin J.A., Morton S.C., et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA 2000, 283:2008-2012.
31. Freeman M.F., Tukey J.W. Transformations related to the angular and the square root. Ann Math Stat 1950, 21:607-611.
32. DerSimonian R., Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986, 7:177-188.
33. Higgins J, Green S. Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from: www.cochrane-handbook.org. [Accessed June 28, 2012].
34. Higgins J.P.T., Thompson S.G., Deeks J.J., et al. Measuring inconsistency in meta-analyses. BMJ 2003, 327:557-560.
35. Modern Epidemiology 1998, Lippincott-Raven, Philadelphia, PA. K. Rothman, S. Greenland (Eds.).
36. Suaya J.A., Shepard D.S., Siqueira J.B., et al. Cost of dengue cases in eight countries in the Americas and Asia: a prospective study. Am J Trop Med Hyg 2009, 80:846-855.
37. Armien B., Suaya J.A., Quiroz E., et al. Clinical characteristics and national economic cost of the 2005 dengue epidemic in Panama. Am J Trop Med Hyg 2008, 79:364-371.
38. Tarragona S, Monteverde M, Marchioni S, et al. La carga económica de dengue en la Argentina: una estimación para la epidemia del año 2009. Trabajo presentado en el 4to congreso de la Asociaciòn Latinoamericana de poblaciòn, realizado en La, 2010, Havana, Cuba.
39. Hammond S.N., Balmaseda A., Perez L., et al. Differences in dengue severity in infants, children, and adults in a 3-year hospital-based study in Nicaragua. Am J Trop Med Hyg 2005, 73:1063-1070.
40. Leiva Herrada C.H., Castro Atarama O., Parra Alejandro J.L. Aspectos clínicos del síndrome de fiebre del dengue con manifestaciones hemorrágicas en pediatría. Diagnóstico (Perú) 2004, 43:23-27.
41. Valdés L., Vila Mizhrahi J., Guzmán M.E. Impacto económico de la epidemia de dengue 2 en Santiago de Cuba, 1997. Rev Cuba Med Trop 2002, 54:220-227.
42. Navarro P., Reyes H., Jakubowicz S., et al. Enfermedades tropicales en niños: una evaluación hospitalaria. Antibiot Infecc 2000, 8:117-121.
43. Ramos M.M., Arguello D.F., Luxemburger C., et al. Epidemiological and clinical observations on patients with dengue in Puerto Rico: results from the first year of enhanced surveillance--June 2005-May 2006. Am J Trop Med Hyg 2008, 79:123-127.
44. Balmaseda A., Standish K., Mercado J.C., et al. Trends in patterns of dengue transmission over 4 years in a pediatric cohort study in Nicaragua. J Infect Dis 2010, 201:5-14.
45. Standish K., Kuan G., Aviles W., et al. High dengue case capture rate in four years of a cohort study in Nicaragua compared to national surveillance data. PLoS Negl Trop Dis 2010, 4(3):e633.
46. Gonçalves Neto V.S., Rebêlo J.M.M. Aspectos epidemiológicos do dengue no Município de São Luís, Maranhão, Brasil, 1997-2002. Cad Saude Publica 2004, 20:1424-1431.
47. Thomas L., Brouste Y., Najioullah F., et al. Etude clinique prospective et descriptive des cas de dengue observes chez l'adulte dans un service d'urgences en Martinique [Prospective and descriptive study of adult dengue cases in an emergency department, in Martinique]. Med Mal Infect 2010, 40:480-489.
48. Camacho T., de la Hoz F., Cardenas V., et al. Incomplete surveillance of a dengue-2 epidemic in Ibagué, Colombia, 1995-1997. Biomedica 2004, 24:174-182.
49. Ribeiro A.F., Marques G.R.A.M., Voltolini J.C., et al. Associacao entre incidencia de dengue e variaveis climaticas [Association between dengue incidence and climatic factors]. Rev Saude Publica 2006, 40:671-676.
50. Rocha LAd, Tauil P.L. Dengue em criança: aspectos clínicos e epidemiológicos, Manaus, Estado do Amazonas, no período de 2006 e 2007. Rev Soc Bras Med Trop 2009, 42:18-22.
51. Santos Ad, Marçal Júnior O, Victoriano MR. Incidência do Dengue na zona urbana do município de Uberlândia, Mg, em 1999. Biosci J 2002;18:33-40.
52. Scandar S.A.S. Análise espacial da distribuição dos casos de dengue e a relação com fatores entomológicos, ambientais e socioeconÔmicos no município de São José do Rio Preto, SP, Brasil 2007, Faculdade de Saúde Pública, Departamento de Epidemiologia, São Paulo.
53. World Health Organization. DengueNet. Available at: [Accessed June 28, 2012]. http://www.who.int/csr/disease/dengue/denguenet/en/index.html.
54. World Health Organization. Working to overcome the global impact of neglected tropical diseases: first WHO report on negleted tropical diseases. 2010. Available from: [Accessed June 28, 2012]. http://whqlibdoc.who.int/publications/2010/9789241564090_eng.pdf.
55. Number of Reported Cases of Dengue and Dengue Hemorrhagic Fever (DHF), Region of the Americas (by Country and Subregion) 2008, Pan American Health Organization, Pan American Health Organization, Washington, DC.
56. Torres J.R., Castro J. The health and economic impact of dengue in Latin America. Cad Saude Publica 2007, 23(Suppl. 1):S23-S31.
57. Reiter P. Texas lifestyle limits transmission of dengue virus. Emerg Infect Dis 2003, 9:86-89.
58. Ramos M.M. Epidemic dengue and dengue hemorrhagic fever at the Texas-Mexico border: result of household-based seroepidemiologic survey, December 2005. Am J Trop Med Hyg 2008, 78:364-369.
59. World Health Organization. Dengue: Guidelines for Diagnosis, Treatment, Prevention and Control-New Edition. Geneva, Switzerland: World Health Organization Special Programme for Research and Training in Tropical Diseases, 2009.
60. Periago M.R., Guzmán M.G. Dengue y dengue hemorrágico en las Américas [editorial]. Rev Panam Salud Publica 2007, 21:187-191.
61. Halstead S.B. Dengue in the Americas and Southeast Asia: do they differ?. Rev Panam Salud Publica 2006, 20:407-415.
62. Teixeira M.G., Costa M.C., Coelho G., et al. Recent shift in age pattern of dengue hemorrhagic fever, Brazil. Emerg Infect Dis 2008, 14:1663.
63. Hotez P.J., Bottazzi M.E., Franco-Paredes C., et al. The neglected tropical diseases of Latin America and the Caribbean: a review of disease burden and distribution and a roadmap for control and elimination. PLoS Negl Trop Dis 2008, 2:e300.
64. Gómez-Dantés H., Willoquet J.R. Dengue in the Americas: challenges for prevention and control. Cad Saude Publica 2009, 25(Suppl. 1):S19-S31.
65. Beatty M.E., Stone A., Fitzsimons D.W., et al. Best practices in dengue surveillance: a report from the Asia-Pacific and Americas Dengue Prevention Boards. PLoS Negl Trop Dis 2010, 4:e890.