Glycidol induces axonopathy and aberrations of hippocampal neurogenesis affecting late-stage differentiation by exposure to rats in a framework of 28-day toxicity study

Toxicology Letters

Volumn 224, Issue 3, 2014, Pages 424-432

  Akane, Hirotoshi ^a   Shiraki, Ayako ^a,b   Imatanaka, Nobuya ^c   Akahori, Yumi ^c   Itahashi, Megu ^a,b   Abe, Hajime ^a,b   Shibutani, Makoto ^a  

^a TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^b GIFU UNIVERSITY   (Japan)

^c CHEMICALS EVALUATION AND RESEARCH INSTITUTE   (Japan)

Author keywords

Axonopathy; Glycidol; Hippocampal dentate gyrus; Neurogenesis; Neurotoxicity

Indexed keywords

4 AMINOBUTYRIC ACID; BETA TUBULIN; CALBINDIN; CASPASE 3; CYCLINE; DOUBLECORTIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCIDOL; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LIOTHYRONINE; MICROTUBULE ASSOCIATED PROTEIN 2; MYELIN ASSOCIATED GLYCOPROTEIN; NERVE CELL ADHESION MOLECULE; NEURON SPECIFIC NUCLEAR PROTEIN; REELIN; THYROTROPIN; THYROXINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPSY; CELL PROLIFERATION; CONTROLLED STUDY; DENTATE GYRUS; DENTATE HILUS; ENVIRONMENTAL EXPOSURE; GABAERGIC SYSTEM; GAIT DISORDER; GRANULE CELL; HIPPOCAMPUS; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; INTERNEURON; MALE; NERVE CELL DIFFERENTIATION; NERVE CELL PLASTICITY; NERVE ENDING; NERVOUS SYSTEM DEVELOPMENT; NEURITE; NEUROPATHY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROGENY; RAT; THYROID HORMONE BLOOD LEVEL;

ANIMALIA; RATTUS;

EID: 84890200394     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.10.026     Document Type: Article

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