The development and implementation of a bundled quality improvement initiative to reduce inappropriate stress ulcer prophylaxis

ICU Director

Volumn 4, Issue 6, 2013, Pages 322-325

  de Leon, Noelle ^a,b   Sharpton, Suzanne ^a   Burg, Cindy ^a,b   Gross, A Kendall ^a,b   Li, Fanny ^a,b   Thompson, Ashley ^a,b   Kobayashi, Robin ^a,b   Vanosdol, Sherilyn J ^b   Tsourounis, Candy ^b   Tasaka, Chelsea ^a,b   Garwood, Charlotte ^a   Bekeart, Rn Lynne ^a,b   Rennke, Stephanie ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Education intervention; Protocol implementation; Quality improvement initiative; Stress ulcer prophylaxis

Indexed keywords

DEXAMETHASONE; FAMOTIDINE; HISTAMINE H2 RECEPTOR ANTAGONIST; HYDROCORTISONE; LANSOPRAZOLE; MEPREDNISONE; PANTOPRAZOLE; PREDNISONE; PROTON PUMP INHIBITOR;

ARTICLE; EVALUATION AND FOLLOW UP; HEALTH CARE COST; HEALTH CARE PERSONNEL; HEALTH CARE PLANNING; HOSPITAL DISCHARGE; HOSPITALIZATION; HUMAN; INTENSIVE CARE; MAJOR CLINICAL STUDY; MEDICAL EDUCATION; PHARMACIST; PRACTICE GUIDELINE; PRIORITY JOURNAL; RISK FACTOR; STRESS ULCER; TOTAL QUALITY MANAGEMENT; UNIVERSITY HOSPITAL;

EID: 84890157030     PISSN: 19444516     EISSN: 19444524     Source Type: Journal    
DOI: 10.1177/1944451613508185     Document Type: Article

References (21)

1. Sesler JM. Stress-related mucosal disease in the intensive care unit: an update on prophylaxis. AACN Adv Crit Care. 2007;18:119-126.
2. Schuster DP, Rowley H, Feinstein S, McGue MK, Zuckerman GR. Prospective evaluation of the risk of upper gastrointestinal bleeding after admission to a medical intensive care unit. Am J Med. 1984;76:623-630.
3. Cook DJ, Witt LG, Cook RJ, Guyatt GH. Stress ulcer prophylaxis in the critically ill: a meta-analysis. Am J Med. 1991;91:519-527.
4. Cook DJ, Fuller HD, Guyatt GH, et al. Risk factors for gastrointestinal bleeding in critically ill patients. N Engl J Med. 1994;330:377-381.
5. Zandstra DF, Stoutenbeek CP. The virtual absence of stress-ulceration related bleeding in ICU patients receiving prolonged mechanical ventilation without any prophylaxis. Intensive Care Med. 1994;20:335-340.
6. ASHP therapeutic guidelines on stress ulcer prophylaxis. Am J Health- Syst Pharm. 1999;56:347-379.
7. Dellinger RP, Levy MM, Rhodes A, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med. 2013;39:165-228.
8. Howell MD, Novack V, Grgurich P, et al. Iatrogenic gastric acid suppression and the risk of nosocomial clostridium difficile infection. Arch Intern Med. 2010;170:784-790.
9. Herzig SJ, Howell MD, Ngo LH, et al. Acid-suppressive medication use and the risk for hospital-acquired pneumonia. JAMA. 2009;301:2120-2128.
10. Alsultan MS, Mayet AY, Malhani AA, Alshaikh MK. Pattern of intravenous proton pump inhibitors use in ICU and non-ICU setting: a prospective observational study. Saudi J Gastroenterol. 2010;16:275-279.
11. Gupta R, Garg P, Kottoor R, et al. Overuse of acid suppression therapy in hospitalized patients. South Med J. 2010;103:207-211.
12. Heidelbaugh JJ, Inadomi JM. Magnitude and economic impact of inappropriate use of stress ulcer prophylaxis in non-ICU hospitalized patients. Am J Gastroenterol. 2006;101:2200-2205.
13. Thomas L, Culley EJ, Gladowski P, Goff V, Fong J, Marche SM. Longitudinal analysis of the costs associated with inpatient initiation and subsequent outpatient continuation of proton pump inhibitor therapy for stress ulcer prophylaxis in a large managed care organization. J Manag Care Pharm. 2010;16: 122-129.
14. American Board of Internal Medicine Foundation. Choosing Wisely® http://www.abimfoundation.org/Initiatives/Choosing-Wisely.aspx. Accessed June 17, 2013.
15. Bulger J, Nickel W, Messler J, et al. Choosing Wisely in adult hospital medicine: five opportunities for improved healthcare value. J Hosp Med. 2013;8:486-492.
16. American Board of Internal Medicine Foundation. ABIM Foundation announces the Choosing Wisely campaign. December 14, 2011. http:// www.abimfoundation.org/News/ABIM-Foundation-News/2011/ABIMFoundation- Announces-the-Choosing-Wisely-Campaign.aspx. Accessed August 18, 2013.
17. Pitimana-aree S, Forrest D, Brown G, Anis A, Wang XH, Dodek P. Implementation of a clinical practice guideline for stress ulcer prophylaxis increases appropriateness and decreases cost of care. Intensive Care Med. 1998;24:217-223.
18. Mostafa G, Sing RF, Matthews BD, Pratt BL, Norton HJ, Heniford BT. The economic benefit of practice guidelines for stress ulcer prophylaxis. Am Surg. 2002;68:146-150.
19. Lin P, Chang CH, Hsu PL, Tseng PL, Huang YB. The efficacy and safety of proton pump inhibitors vs histamine-2 receptor antagonists for stress ulcer bleeding prophylaxis among critical care patients: a meta-analysis. Crit Care Med. 2010;38:1197-1205.
20. Barkun AN, Bardou M, Pham CQ, Martel M. Proton pump inhibitors vs histamine 2 receptor antagonists for stress-related mucosal bleeding prophylaxis in critically ill patients: a meta analysis. Am J Gastroenterol. 2012;107:507-520.
21. Alhazzani W, Alenezi F, Jaeschke RZ, et al. Proton pump inhibitors versus histamine 2 receptor antagonists for stress ulcer prophylaxis in critically ill patients: a systemic review and meta-analysis. Crit Care Med. 2013;41:693-705.