The role of serotonin receptor alleles and environmental stressors in the development of post-concussive symptoms after pediatric mild traumatic brain injury

Developmental Medicine and Child Neurology

Volumn 56, Issue 1, 2014, Pages 73-77

  Smyth, Kim ^a   Sandhu, Sandeep S ^b   Crawford, Susan ^b   Dewey, Deborah ^b   Parboosingh, Jillian ^c   Barlow, Karen M ^a,b  

^a ALBERTA CHILDREN'S HOSPITAL   (Canada)

^b ALBERTA CHILDREN S HOSPITAL RESEARCH INSTITUTE   (Canada)

^c UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ALLELE; ARTICLE; CHILD; CHILDREN DEPRESSION INVENTORY; CLINICAL ARTICLE; DEPRESSION; DNA DETERMINATION; ENVIRONMENTAL STRESS; FEMALE; GENE; GENE FREQUENCY; GENOTYPE; HEREDITY; HTR1A GENE; HUMAN; INFANT; LIFE STRESS; MALE; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; OUTCOME ASSESSMENT; POSTCONCUSSION SYMPTOMS INVENTORY; POSTCONCUSSION SYNDROME; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; STRESSFUL LIFE EVENTS QUESTIONNAIRE; TRAUMATIC BRAIN INJURY;

ADOLESCENT; BRAIN INJURIES; CHILD; CROSS-SECTIONAL STUDIES; CYSTEINE; FEMALE; GENE FREQUENCY; GENOTYPE; GLYCINE; HUMANS; LIFE CHANGE EVENTS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; POST-CONCUSSION SYNDROME; QUESTIONNAIRES; RECEPTOR, SEROTONIN, 5-HT1A; RISK FACTORS; STRESS, PSYCHOLOGICAL;

EID: 84890156323     PISSN: 00121622     EISSN: 14698749     Source Type: Journal    
DOI: 10.1111/dmcn.12263     Document Type: Article

References (27)

1. Langlois JA, Rutland-Brown W, Thomas KE. The incidence of traumatic brain injury among children in the United States: differences by race. J Head Trauma Rehabil 2005; 20: 29-38.
2. McKinlay A, Grace RC, Horwood LJ, Fergusson DM, Ridder EM, MacFarlane MR. Prevalence of traumatic brain injury among children, adolescents and young adults: prospective evidence from a birth cohort. Brain Inj 2008; 22: 175-81.
3. Yeates KO, Taylor HG, Rusin J, et al. Longitudinal trajectories of post concussive symptoms in children with mild traumatic brain injuries and their relationship to acute clinical status. Pediatrics 2009; 123: 735-43.
4. Kirkwood MW, Yeates KO, Taylor GH, Randolph C, McCrea M, Anderson VA. Management of pediatric mild traumatic brain injury: a neuropsychological review from injury through recovery. Clin Neuropsychol 2008; 22: 769-800.
5. Taylor HG, Dietrich A, Nuss K, et al. Post-concussive symptoms in children with mild traumatic brain injury. Neuropsychology 2010; 24: 148-59.
6. Barlow KM, Crawford S, Stevenson A, Sandhu SS, Belanger F, Dewey D. Epidemiology of postconcussion syndrome in pediatric mild traumatic brain injury. Pediatrics 2010; 126: 374-81.
7. Giza CC, Hovda DA. The neurometabolic cascade of concussion. J Athl Train 2001; 36: 228-35.
8. Shrey DW, Griesbach GS, Giza CC. The pathophysiology of concussions in youth. Phys Med Rehabil Clin N Am 2011; 22: 577-602.
9. Iverson GL. Outcome from mild traumatic brain injury. Curr Opin Psychiatry 2005; 18: 301-17.
10. Bay E, Donders J. Risk factors for depressive symptoms after mild-to-moderate traumatic brain injury. Brain Inj 2008; 22: 233-41.
11. Ponsford J, Willmott C, Rothwell A, et al. Cognitive and behavioral outcome following mild traumatic brain injury in children. J Head Trauma Rehabil 1999; 14: 360-72.
12. Busch CR, Alpern HC. Depression after mild traumatic brain injury: a review of current research. Neuropsychol Rev 1998; 8: 95-108.
13. Vanderploeg RD, Curtiss G, Luis CA, Salazar AM. Long-term morbidities following self-reported mild traumatic brain injury. J Clin Exp Neuropsychol 2007; 29: 585-98.
14. Massagli TL, Fann JR, Burington BE, Jaffe KM, Katon WJ, Thompson RS. Psychiatric illness after mild traumatic brain injury in children. Arch Phys Med Rehabil 2004; 85: 1428-34.
15. Max JE, Robin DA, Lindgren SD, et al. Traumatic brain injury in children and adolescents: psychiatric disorders at two years. J Am Acad Child Adolesc Psychiatry 1997; 36: 1278-85.
16. Max JE, Keatley E, Wilde EA, Bigler ED, Schachar RJ, Saunders AE. Depression in children and adolescents in the first 6 months after traumatic brain injury. Int J Dev Neurosci 2012; 30: 239-45.
17. Bloom DR, Levin HS, Ewing-Cobbs L, Saunders AE, Song J, Kowatch RA. Lifetime and novel psychiatric disorders after pediatric traumatic brain injury. J Am Acad Child Adolesc Psychiatry 2001; 40: 572-9.
18. Luis CA, Mittenberg W. Mood and anxiety disorders following pediatric traumatic brain injury: a prospective study. J Clin Exp Neuropsychol 2002; 24: 270-9.
19. Patten SB. Childhood and adult stressors and major depression risk: interpreting interactions with the sufficient-component cause model. Soc Psychiatry Psychiatr Epidemiol 2013; 48: 927-33.
20. Jorge RE, Robinson RG, Arndt SV, Starkstein SE, Forrester AW, Geisler F. Depression following traumatic brain injury: a 1 year longitudinal study. J Affect Disord 1993; 27: 233-43.
21. Lemonde S, Turecki G, Bakish D, et al. Impaired repression at a 5-hydroxytryptamine 1A receptor gene polymorphism associated with major depression and suicide. J Neurosci 2003; 23: 8788-99.
22. Glass KL, Natale MJ, Janusz GA, Gioia GA, Anderson S. Initial Development of a Parent Report of Post Concussion Symptoms in Children and Adolescents. Paper presented at: the annual meeting of the International Neuropsychological Society; February 2-5, 2005; St Louis, MO, USA.
23. Smucker MR, Craighead WE, Craighead LW, Green BJ. Normative and reliability data for the Children's Depression Inventory. J Abnorm Child Psychol 1986; 14: 25-39.
24. Coddington RD. The significance of life events as etiologic factors in the diseases of children-II: a study of a normal population. J Psychosom Res 1972; 16: 205-13.
25. Chan F, Lanctot KL, Feinstein A, et al. The serotonin transporter polymorphisms and major depression following traumatic brain injury. Brain Inj 2008; 22: 471-9.
26. Knight D, Hensley VR, Waters B. Validation of the Children's Depression Scale and the Children's Depression Inventory in a prepubertal sample. J Child Psychol Psychiatry 1988; 29: 853-63.
27. Grant KE, Compas BE, Thurm AE, et al. Stressors and child and adolescent psychopathology: measurement issues and prospective effects. J Clin Child Adolesc Psychol 2004; 33: 412-25.