Core-Shell type lipid/rPAA-Chol polymer hybrid nanoparticles for invivo siRNA delivery

Biomaterials

Volumn 35, Issue 6, 2014, Pages 2066-2078

  Gao, Ling Yan ^a   Liu, Xiao Yan ^a   Chen, Cheng Jun ^a   Wang, Jian Cheng ^a   Feng, Qiang ^a   Yu, Min Zhi ^a   Ma, Xiao Fei ^a   Pei, Xi Wei ^a   Niu, Yu Jie ^a   Qiu, Chong ^a   Pang, Wen Hao ^a   Zhang, Qiang ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Core Shell hybrid nanoparticle; Receptor mediated targeting; SiRNA delivery; Tumor therapy

Indexed keywords

CELLULAR UPTAKE EFFICIENCY; CONFOCAL LASER SCANNING MICROSCOPE; CORE-SHELL HYBRIDS; PROTEIN EXPRESSION LEVELS; RECEPTOR-MEDIATED TARGETING; SIRNA DELIVERY; SYSTEMIC ADMINISTRATION; TUMOR THERAPY;

DYNAMIC LIGHT SCATTERING; PEPTIDES; PHOSPHOLIPIDS; RNA; SHELLS (STRUCTURES); SURFACE PLASMON RESONANCE; TRANSMISSION ELECTRON MICROSCOPY; TUMORS;

NANOPARTICLES;

CHOLESTEROL GRAFTED POLY(AMIDOAMINE); LIPOPLEX; NANOPARTICLE; PHOSPHOLIPID DERIVATIVE; POLYAMIDOAMINE; POLYETHYLENE GLYCOL PHOSPHOLIPID; SMALL INTERFERING RNA; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CANCER THERAPY; CELL STRAIN MCF 7; COMPARATIVE STUDY; CONFOCAL LASER MICROSCOPY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; ELECTRON MICROSCOPE; GENE SILENCING; GENETIC TRANSFECTION; IMMUNE RESPONSE; IN VIVO STUDY; LIGHT SCATTERING; LIPID BILAYER; MOUSE; NONHUMAN; NUDE MOUSE; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCANNING ELECTRON MICROSCOPE; SURFACE PLASMON RESONANCE; TUMOR GROWTH; WEIGHT REDUCTION;

MUS MUSCULUS;

CORE-SHELL HYBRID NANOPARTICLE; RECEPTOR-MEDIATED TARGETING; SIRNA DELIVERY; TUMOR THERAPY;

ANIMALS; CELL SURVIVAL; FLOW CYTOMETRY; HUMANS; MCF-7 CELLS; MICE; MICROSCOPY, CONFOCAL; NANOPARTICLES; POLYETHYLENE GLYCOLS; POLYMERS; RNA, SMALL INTERFERING; SURFACE PLASMON RESONANCE;

EID: 84890132867     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.11.046     Document Type: Article

References (38)

1. Reynolds A., Leake D., Boese Q., Scaringe S., Marshall W.S., Khvorova A. Rational siRNA design for RNA interference. Nat Biotechnol 2004, 22:326-330.
2. Davis M.E., Zuckerman J.E., Choi C.H., Seligson D., Tolcher A., Alabi C.A., et al. Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature 2010, 464:1067-1070.
3. Alvarez-Erviti L., Seow Y., Yin H., Betts C., Lakhal S., Wood M.J. Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes. Nat Biotechnol 2011, 29:341-345.
4. Oh Y.K., Park T.G. siRNA delivery systems for cancer treatment. Adv Drug Deliv Rev 2009, 61:850-862.
5. Guo S., Qiao Y., Wang W., He H., Deng L., Xing J., et al. Poly(ε-caprolactone)-graft-poly(2-(N, N-dimethylamino) ethyl methacrylate) nanoparticles: pH dependent thermo-sensitive multifunctional carriers for gene and drug delivery. JMater Chem 2010, 20:6935-6941.
6. Judge A.D., Sood V., Shaw J.R., Fang D., McClintock K., MacLachlan I. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol 2005, 23:457-462.
7. Guo S., Huang Y., Zhang W., Wang W., Wei T., Lin D., et al. Ternary complexes of amphiphilic polycaprolactone-graft-poly (N,N-dimethylaminoethyl methacrylate), DNA and polyglutamic acid-graft-poly(ethylene glycol) for gene delivery. Biomaterials 2011, 32:4283-4292.
8. Gu J., Wang X., Jiang X., Chen Y., Chen L., Fang X., et al. Self-assembled carboxymethyl poly (L-histidine) coated poly (beta-amino ester)/DNA complexes for gene transfection. Biomaterials 2012, 33:644-658.
9. Huang Y., Lin D., Jiang Q., Zhang W., Guo S., Xiao P., et al. Binary and ternary complexes based on polycaprolactone-graft-poly (N, N-dimethylaminoethyl methacrylate) for targeted siRNA delivery. Biomaterials 2012, 33:4653-4664.
10. Mansouri S., Lavigne P., Corsi K., Benderdour M., Beaumont E., Fernandes J.C. Chitosan-DNA nanoparticles as non-viral vectors in gene therapy: strategies to improve transfection efficacy. Eur J Pharm Biopharm 2004, 57:1-8.
11. Jiang M., Gan L., Zhu C., Dong Y., Liu J., Gan Y. Cationic core-shell liponanoparticles for ocular gene delivery. Biomaterials 2012, 33:7621-7630.
12. Li S.D., Huang L. Surface-modified LPD nanoparticles for tumor targeting. Ann N Y Acad Sci 2006, 1082:1-8.
13. Hatakeyama H., Akita H., Kogure K., Oishi M., Nagasaki Y., Kihira Y., et al. Development of a novel systemic gene delivery system for cancer therapy with a tumor-specific cleavable PEG-lipid. Gene Ther 2007, 14:68-77.
14. Hatakeyama H., Akita H., Ito E., Hayashi Y., Oishi M., Nagasaki Y., et al. Systemic delivery of siRNA to tumors using a lipid nanoparticle containing a tumor-specific cleavable PEG-lipid. Biomaterials 2011, 32:4306-4316.
15. Mandal B., Bhattacharjee H., Mittal N., Sah H., Balabathula P., Thoma L.A., et al. Core-shell-type lipid-polymer hybrid nanoparticles as a drug delivery platform. Nanomed Nanotechnol Biol Med 2013, 9:474-491.
16. Chen C.J., Wang J.C., Zhao E.Y., Gao L.Y., Feng Q., Liu X.Y., et al. Self-assembly cationic nanoparticles based on cholesterol-grafted bioreducible poly(amidoamine) for siRNA delivery. Biomaterials 2013, 34:5303-5316.
17. Lee J.H., Engler J.A., Collawn J.F., Moore B.A. Receptor mediated uptake of peptides that bind the human transferrin receptor. Eur J Biochem 2001, 268:2004-2012.
18. Daniels T.R., Bernabeu E., Rodriguez J.A., Patel S., Kozman M., Chiappetta D.A., et al. The transferrin receptor and the targeted delivery of therapeutic agents against cancer. Biochim Biophys Acta 2012, 1820:291-317.
19. Chen C.J., Zhao Z.X., Wang J.C., Zhao E.Y., Gao L.Y., Zhou S.F., et al. Acomparative study of three ternary complexes prepared in different mixing orders of siRNA/redox-responsive hyperbranched poly (amido amine)/hyaluronic acid. Int J Nanomed 2012, 7:3837-3849.
20. Houghton P., Fang R., Techatanawat I., Steventon G., Hylands P.J., Lee C.C. The sulphorhodamine (SRB) assay and other approaches to testing plant extracts and derived compounds for activities related to reputed anticancer activity. Methods 2007, 42:377-387.
21. Jiang G., Park K., Kim J., Kim K.S., Hahn S.K. Target specific intracellular delivery of siRNA/PEI-HA complex by receptor mediated endocytosis. Mol Pharmacol 2009, 6:727-737.
22. Li S.D., Chen Y.C., Hackett M.J., Huang L. Tumor-targeted delivery of siRNA by self-assembled nanoparticles. Mol Ther 2008, 16:163-169.
23. Won Y., Brannan A.K., Davis H.T., Bates F.S. Cryogenic transmission electron microscopy (Cryo-TEM) of micelles and vesicles formed in water by poly(ethylene oxide)-based block copolymers. JPhys Chem B 2002, 106:3354-3364.
24. Jackson C.L., Chanzy H.D., Booy F.P., Drake B.J., Tomalia D.A., Bauer B.J., et al. Visualization of dendrimer molecules by transmission electron microscopy (TEM): staining methods and Cryo-TEM of vitrified solutions. Macromolecules 1998, 31:6259-6265.
25. Tan S.J., Kiatwuthinon P., Roh Y.H., Kahn J.S., Luo D. Engineering nanocarriers for siRNA delivery. Small 2011, 7:841-856.
26. Han S.E., Kang H., Shim G.Y., Suh M.S., Kim S.J., Kim J.S., et al. Novel cationic cholesterol derivative-based liposomes for serum-enhanced delivery of siRNA. Int J Pharm 2008, 353:260-269.
27. Katas H., Alpar H.O. Development and characterisation of chitosan nanoparticles for siRNA delivery. JControl Release 2006, 115:216-225.
28. Luo D., Saltzman W.M. Synthetic DNA delivery systems. Nat Biotechnol 2000, 18:33-37.
29. Yao D., Ehrlich M., Henis Y.I., Leof E.B. Transforming growth factor-beta receptors interact with AP2 by direct binding to beta2 subunit. Mol Biol Cell 2002, 13:4001-4012.
30. Sharma D.K., Choudhury A., Singh R.D., Wheatley C.L., Marks D.L., Pagano R.E. Glycosphingolipids internalized via caveolar-related endocytosis rapidly merge with the clathrin pathway in early endosomes and form microdomains for recycling. JBiol Chem 2003, 278:7564-7572.
31. Ivanov A.I., Nusrat A., Parkos C.A. Endocytosis of epithelial apical junctional proteins by a clathrin-mediated pathway into a unique storage compartment. Mol Biol Cell 2004, 15:176-188.
32. Resnier P., Montier T., Mathieu V., Benoit J.P., Passirani C. Areview of the current status of siRNA nanomedicines in the treatment of cancer. Biomaterials 2013, 34:6429-6443.
33. Panyam J., Zhou W.Z., Prabha S., Sahoo S.K., Labhasetwar V. Rapid endo-lysosomal escape of poly(DL-lactide-co-glycolide) nanoparticles: implications for drug and gene delivery. FASEB J 2002, 16:1217-1226.
34. Keswani R.K., Pozdol I.M., Pack D.W. Design of hybrid lipid/retroviral-like particle gene delivery vectors. Mol Pharm 2013, 10:1725-1735.
35. Lu J.J., Langer R., Chen J. Anovel mechanism is involved in cationic lipid-mediated functional siRNA delivery. Mol Pharm 2009, 6:763-771.
36. Huang L., Liu Y. Invivo delivery of RNAi with lipid-based nanoparticles. Annu Rev Biomed Eng 2011, 13:507-530.
37. Diagaradjane P., Orenstein-Cardona J.M., Colon-Casasnovas N.E., Deorukhkar A., Shentu S., Kuno N., et al. Imaging epidermal growth factor receptor expression invivo: pharmacokinetic and biodistribution characterization of a bioconjugated quantum dot nanoprobe. Clin Cancer Res 2008, 14:731-741.
38. Jiang J., Yang S.J., Wang J.C., Yang L.J., Xu Z.Z., Yang T., et al. Sequential treatment of drug-resistant tumors with RGD-modified liposomes containing siRNA or doxorubicin. Eur J Pharm Biopharm 2010, 76:170-178.