Highly sensitive and selective analysis of widely targeted metabolomics using gas chromatography/triple-quadrupole mass spectrometry

Journal of Bioscience and Bioengineering

Volumn 117, Issue 1, 2014, Pages 122-128

  Tsugawa, Hiroshi ^a,b   Tsujimoto, Yuki ^a   Sugitate, Kuniyo ^c   Sakui, Norihiro ^c   Nishiumi, Shin ^d   Bamba, Takeshi ^a   Fukusaki, Eiichiro ^a  

^a OSAKA UNIVERSITY   (Japan)

^b RIKEN Center for Sustainable Resource Science   (Japan)

^c YOKOGAWA ANALYTICAL SYSTEMS INC   (Japan)

^d KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Gas chromatography coupled with triple quadrupole mass spectrometry; Multichannel selected reaction monitoring transitions; Selected reaction monitoring; Sensitivity; Widely targeted metabolomics

Indexed keywords

BIO-MARKER DISCOVERY; MATHEMATICAL PARAMETERS; METABOLOMICS; QUADRUPOLE MASS SPECTROMETRY; SELECTED REACTION MONITORING; SENSITIVITY; TRIMETHYLSILYL DERIVATIVES; TRIPLE-QUADRUPOLE MASS SPECTROMETRY;

BIOLOGY; BIOMOLECULES; GAS CHROMATOGRAPHY; IONIZATION OF GASES; MASS SPECTROMETRY; METABOLITES;

QUALITY CONTROL;

2 OXOISOVALERIC ACID; 3 HYDROXYBUTYRIC ACID; ALANINE; BETA ALANINE; BUTYLAMINE; FUMARIC ACID; GLYCERIC ACID; GLYCEROL; GLYCINE; GLYCOLIC ACID; HYDROXYBUTYRIC ACID; ISOLEUCINE; LACTIC ACID; LEUCINE; NICOTINAMIDE; NONANOIC ACID; OCTANOIC ACID; OXALOACETIC ACID; PHOSPHORIC ACID; PROLINE; PROPYLAMINE; PYRUVIC ACID; SERINE; SUCCINIC ACID; THREONINE; THYMINE; TRIMETHYLSILYL DERIVATIVE; URACIL; UREA; VALINE; PLASMA PROTEIN;

ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; ELECTRON; GAS CHROMATOGRAPHY; IONIZATION; LIMIT OF DETECTION; METABOLITE; METABOLOMICS; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; QUADRUPOLE MASS SPECTROMETRY; SACCHAROMYCES CEREVISIAE; ANIMAL; C57BL MOUSE; MASS FRAGMENTOGRAPHY; METABOLISM; PROCEDURES; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

ANIMALS; BLOOD PROTEINS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; METABOLOMICS; MICE; MICE, INBRED C57BL; REPRODUCIBILITY OF RESULTS; SACCHAROMYCES CEREVISIAE; SENSITIVITY AND SPECIFICITY;

EID: 84890128184     PISSN: 13891723     EISSN: 13474421     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2013.06.009     Document Type: Article

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