Use of the Cultex Radial Flow System as an in vitro exposure method to assess acute pulmonary toxicity of fine dusts and nanoparticles with special focus on the intra- and inter-laboratory reproducibility

Chemico-Biological Interactions

Volumn 206, Issue 3, 2013, Pages 479-490

  Steinritz, Dirk ^a,b   Möhle, Niklas ^c   Pohl, Christine ^d   Papritz, Mirko ^a   Stenger, Bernhard ^d   Schmidt, Annette ^a   Kirkpatrick, Charles James ^d   Thiermann, Horst ^a   Vogel, Richard ^f   Hoffmann, Sebastian ^e   Aufderheide, Michaela ^c  

^a BUNDESWEHR INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c Cultex Laboratories GmbH   (Germany)

^d JOHANNES GUTENBERG UNIVERSITY   (Germany)

^e Seh Consulting + Services   (Germany)

^f Berlin Statistical Office   (Germany)

Author keywords

Aerosols; Air liquid interface; Cultex RFS; In vitro toxicity; Lung toxicity; REACH

Indexed keywords

BARIUM SULFATE; CARBON; CERIUM OXIDE; COPPER SULFATE; LACTOSE; MAGNESIUM OXIDE; NANOPARTICLE; TITANIUM DIOXIDE; DUST; METAL NANOPARTICLE; PARTICULATE MATTER;

AEROSOL; AIR QUALITY CONTROL; AIRFLOW; ARTICLE; CANCER CELL CULTURE; CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; DUST; ENVIRONMENTAL EXPOSURE; FLOW KINETICS; GENERATOR; HAZARD ASSESSMENT; HUMAN; HUMAN CELL; HYDRAULIC CONDUCTIVITY; IN VITRO STUDY; LUNG TOXICITY; PARTICLE SIZE; RADIAL FLOW SYSTEM; REPRODUCIBILITY; RISK ASSESSMENT; TOXICITY TESTING; ANALYSIS; CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; EVALUATION STUDY; EXPOSURE; LUNG ALVEOLUS CELL; PARTICULATE MATTER; PATHOLOGY; PROCEDURES; STATISTICS AND NUMERICAL DATA; TOXICITY; VALIDATION STUDY; AIR-LIQUID-INTERFACE; CULTEX® RFS; DRUG EFFECT; IN VITRO TOXICITY; METHODOLOGY; REACH; STATISTICS;

ANIMALIA;

CELL LINE; CELL SURVIVAL; DUST; HUMANS; INHALATION EXPOSURE; METAL NANOPARTICLES; PARTICULATE MATTER; PNEUMOCYTES; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; TOXICITY TESTS, ACUTE;

AEROSOLS; AIR-LIQUID-INTERFACE; CULTEX® RFS; IN VITRO TOXICITY; LUNG TOXICITY; REACH;

EID: 84890125623     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2013.05.001     Document Type: Article

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