Association of hormonal contraceptive usewith reduced levels of depressive symptoms: A national study of sexually activewomen in the united states

American Journal of Epidemiology

Volumn 178, Issue 9, 2013, Pages 1378-1388

  Keyes, Katherine M ^a   Cheslack Postava, Keely ^a   Westhoff, Carolyn ^a   Heim, Christine M ^b   Haloossim, Michelle ^a   Walsh, Kate ^a   Koenen, Karestan ^a  

^a Columbia University ^*  (United States)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Adolescent; Depression; Gender; Hormonal contraception; Oral contraceptives; Suicide

Indexed keywords

LEVONORGESTREL; MEDROXYPROGESTERONE ACETATE;

ADOLESCENCE; CONTRACEPTIVE USE; EPIDEMIOLOGY; ESTROGENIC COMPOUND; HEALTH SURVEY; HORMONE; SEXUAL BEHAVIOR; SYMPTOM; WOMENS HEALTH;

ADULT; ARTICLE; BIRTH CONTROL; CONTRACEPTIVE BEHAVIOR; DEPRESSION; FEMALE; HORMONAL CONTRACEPTION; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; PROPENSITY SCORE; SEXUAL BEHAVIOR; SUICIDE ATTEMPT; UNITED STATES;

ADOLESCENT; DEPRESSION; GENDER; HORMONAL CONTRACEPTION; ORAL CONTRACEPTIVES; SUICIDE;

ADOLESCENT; ADULT; BODY MASS INDEX; CONTRACEPTIVE AGENTS, FEMALE; DEPRESSION; ESTROGENS; EXERCISE; FEMALE; HEALTH BEHAVIOR; HEALTH STATUS; HUMANS; LONGITUDINAL STUDIES; PROGESTINS; PROPENSITY SCORE; SEXUAL BEHAVIOR; SMOKING; SOCIOECONOMIC FACTORS; SUICIDE, ATTEMPTED; UNITED STATES;

UNITED STATES;

EID: 84890108662     PISSN: 00029262     EISSN: 14766256     Source Type: Journal    
DOI: 10.1093/aje/kwt188     Document Type: Article

References (70)

1. Chandra A, Martinez GM, Mosher WD, et al. Fertility, family planning, and reproductive health of U.S. women: Data from the 2002 National Survey of Family Growth. Vital Health Stat 23. 2005;(25):1-160.
2. Kaunitz AM. Oral contraceptive health benefits: Perception versus reality. Contraception. 1999;59(suppl 1):29S-33S.
3. King J. Noncontraceptive uses of hormonal contraception. J Midwif Wom Health. 2011;56(6):628-635.
4. Maguire K,Westhoff C. The state of hormonal contraception today: Established and emerging noncontraceptive health benefits. Am J Obstet Gynecol. 2011;205(suppl 4):S4-S8.
5. Shufelt CL, Bairey Merz CN. Contraceptive hormone use and cardiovascular disease. J Am Coll Cardiol. 2009;53(3): 221-231.
6. Hasin DS, Goodwin RD, Stinson FS, et al. Epidemiology of major depressive disorder: Results from the National Epidemiologic Survey on Alcoholism and Related Conditions. Arch Gen Psychiatry. 2005;62(10):1097-1106.
7. Rushton JL, Forcier M, Schectman RM. Epidemiology of depressive symptoms in the National Longitudinal Study of Adolescent Health. J Am Acad Child Adolesc Psychiatry. 2002;41(2):199-205.
8. Wight RG, Sepulveda JE, Aneshensel CS. Depressive symptoms: How do adolescents compare with adults J Adolesc Health. 2004;34(4):314-323.
9. McEwen BS. Invited review: Estrogens effects on the brain: Multiple sites and molecular mechanisms. J Appl Physiol. 2001;91(6):2785-2801.
10. Schmidt PJ, Nieman LK, Danaceau MA, et al. Differential behavioral effects of gonadal steroids in women with and in those without premenstrual syndrome. N Engl J Med. 1998;338(4):209-216.
11. Joffe H, Cohen LS. Estrogen, serotonin, and mood disturbance: Where is the therapeutic bridge Biol Psychiatry. 1998;44(9):798-811.
12. Payne JL. The role of estrogen in mood disorders in women. Int Rev Psychiatry. 2003;15(3):280.
13. Cohen LS, Soares CN, Vitonis AF, et al. Risk for new onset of depression during the menopausal transition: The Harvard study of moods and cycles. Arch Gen Psychiatry. 2006; 63(4):385-390.
14. Young EA, Midgley AR, Carlson NE, et al. Alteration in the hypothalamic-pituitary-ovarian axis in depressed women. Arch Gen Psychiatry. 2000;57(12):1157-1162.
15. Harlow BL,Wise LA, Otto MW, et al. Depression and its influence on reproductive endocrine and menstrual cycle markers associated with perimenopause: The Harvard Study of Moods and Cycles. Arch Gen Psychiatry. 2003;60(1): 29-36.
16. Duke JM, Sibbritt DW, Young AF. Is there an association between the use of oral contraception and depressive symptoms in young Australian women Contraception. 2007;75(1):27-31.
17. Joffe H, Cohen LS, Harlow BL. Impact of oral contraceptive pill use on premenstrual mood: Predictors of improvement and deterioration. Am J Obstet Gynecol. 2003;189(6):1523-1530.
18. Toffol E, Heikinheimo O, Koponen P, et al. Hormonal contraception and mental health: Results of a population-based study. Hum Reprod. 2011;26(11):3085-3093.
19. Hannaford PC, Iversen L, Macfarlane TV, et al. Mortality among contraceptive pill users: Cohort evidence from Royal College of General Practitioners' Oral Contraception Study. BMJ. 2010;340:c927.
20. Colditz GA. Oral contraceptive use and mortality during 12 years of follow-up: The Nurses' Health Study. Ann Intern Med. 1994;120(10):821-826.
21. Vessey M, Painter R, Yeates D. Mortality in relation to oral contraceptive use and cigarette smoking. Lancet. 2003; 362(9379):185-191.
22. Nock MK, Borges G, Bromet EJ, et al. Suicide and suicidal behavior. Epidemiol Rev. 2008;30:133-154.
23. Harris KM. The National Longitudinal Study of Adolescent Health (Add Health), Waves I & II, 1994-1996; Wave III, 2001-2002; Wave IV, 2007-2009 [machine-readable data file and documentation]. Chapel Hill, NC: Carolina Population Center, University of North Carolina at Chapel Hill; 2009.
24. Trussell J. Contraceptive efficacy. In: Hatcher RA, Trussell J, Nelson J, et al, eds. Contraceptive Technology: Nineteenth Revised Edition. New York, NY: Ardent Media; 2007:19-41.
25. Mosher WD, Jones J. Use of contraception in the United States: 1982-2008. Vital Health Stat 23. 2010;(29):1-44.
26. Andresen EM, Malmgren JA, Carter WB, et al. Screening for depression in well older adults: Evaluation of a short form of the CES-D (Center for Epidemiologic Studies Depression Scale). Am J Prev Med. 1994;10(2):77-84.
27. Radloff LS. The CES-D Scale: A self-report depression scale for research in the general population. Appl Psychol Meas. 1977;1(3):385-401.
28. Boey KW. Cross-validation of a short form of the CES-D in Chinese elderly. Int J Geriatr Psychiatry. 1999;14(8):608-617.
29. Bradley KL, Bagnell AL, Brannen CL. Factorial validity of the Center for Epidemiological Studies Depression 10 in adolescents. Issues Ment Health Nurs. 2010;31(6): 408-412.
30. Brewster KL, Cooksey EC, Guilkey DK, et al. The changing impact of religion on the sexual and contraceptive behavior of adolescent women in the United States. J Marriage Fam. 1998;60(2):493-504.
31. Goldscheider C, Mosher WD. Patterns of contraceptive use in the United States: The importance of religious factors. Stud Fam Plann. 1991;22(2):102-115.
32. Westgate CE. Spiritual wellness and depression. J Counsel Develop. 1996;75(1):26-35.
33. Little RJ, Vartivarian S. On weighting the rates in nonresponse weights. Stat Med. 2003;22(9):1589-1599.
34. Austin PC. The performance of different propensity-score methods for estimating relative risks. J Clin Epidemiol. 2008;61(6):537-545.
35. Rosenberg MJ,Waugh MS, Long S. Unintended pregnancies and use, misuse and discontinuation of oral contraceptives. J Reprod Med. 1995;40(5):355-360.
36. Ali M, Cleland JL. Contraceptive discontinuation in six developing countries: A cause-specific analysis. Int Fam Plann Perspect. 1995;21(3):92-97.
37. Hall KS, White KO, Rickert VI, et al. Influence of depressed mood and psychological stress symptoms on perceived oral contraceptive side effects and discontinuation in young minority women. Contraception. 2012;86(5):518-525.
38. Westhoff CL, Heartwell S, Edwards S, et al. Oral contraceptive discontinuation: Do side effects matter Am J Obstet Gynecol. 2007;196(4):412.e1-412.e6.
39. Nelson AL,Westhoff C, Schnare SM. Real-world patterns of prescription refills for branded hormonal contraceptives: A reflection of contraceptive discontinuation. Obstet Gynecol. 2008;112(4):782-787.
40. Garbers S, Correa N, Tobier N, et al. Association between symptoms of depression and contraceptive method choices among low-income women at urban reproductive health centers. Matern Child Health J. 2010;14(1):102-109.
41. Herzberg BN, Draper KC, Johnson AL, et al. Oral contraceptives, depression, and libido. BMJ. 1971;3(5773):495-500.
42. Borgstrom A, Odlind V, Ekselius L, et al. Adverse mood effects of combined oral contraceptives in relation to personality traits. Eur J Obstet Gynecol Reprod Biol. 2008; 141(2):127-130.
43. Borgstrom A, Kask K, Gulinello M, et al. Patients with adverse mood effects from combined oral contraceptives have lower levels of prepulse inhibition than healthy controls. Psychoneuroendocrinology. 2008;33(4):487-496.
44. Ernst U, Baumgartner L, Bauer U, et al. Improvement of quality of life in women using a low-dose desogestrelcontaining contraceptive: Results of an observational clinical evaluation. Eur J Contracept Reprod Health Care 2002; 7(4):238-243.
45. Robinson SA, Dowell M, Pedulla D, et al. Do the emotional side-effects of hormonal contraceptives come from pharmacologic or psychological mechanisms Med Hypoth. 2004;63(2):268-273.
46. Westhoff C, Truman C, Kalmuss D, et al. Depressive symptoms and Norplant contraceptive implants. Contraception. 1998;57(4):241-245.
47. Sanders SA, Graham CA, Bass JL, et al. A prospective study of the effects of oral contraceptives on sexuality and wellbeing and their relationship to discontinuation. Contraception. 2001;64(1):51-58.
48. Wiebe ER, Brotto LA, MacKay J. Characteristics of women who experience mood and sexual side effects with use of hormonal contraception. J Obstet Gynaecol Can. 2011; 33(12):1234-1240.
49. Kalmuss D, Koenemann S,Westhoff C, et al. Prior pill experiences and current continuation among pill restarters. Perspect Sex Reprod Health. 2008;40(3):138-143.
50. O'Connell K, Davis AR, Kerns J. Oral contraceptives: Side effects and depression in adolescent girls. Contraception. 2007;75(4):299-304.
51. Walker A, Bancroft J. Relationship between premenstrual symptoms and oral contraceptive use: A controlled study. Psychosom Med. 1990;52(1):86-96.
52. Graham CA, Sherwin BB. A prospective treatment study of premenstrual symptoms using a triphasic oral contraceptive. J Psychosom Res. 1992;36(3):257-266.
53. Sadler C, Smith H, Hammond J, et al. Lifestyle factors, hormonal contraception, and premenstrual symptoms: The United Kingdom SouthamptonWomen's Survey. J Womens Health (Larchmt). 2010;19(3):391-396.
54. Almagor M, Ben-Porath YS. Mood changes during the menstrual cycle and their relation to the use of oral contraceptive. J Psychosom Res. 1991;35(6):721-728.
55. Heiman JR, Rupp H, Janssen E, et al. Sexual desire, sexual arousal and hormonal differences in premenopausal US and Dutch women with and without low sexual desire. Horm Behav. 2011;59(5):772-779.
56. Nappi RE, Albani F, Tonani S, et al. Psychosexual well-being in women using oral contraceptives containing drospirenone. Funct Neurol. 2009;24(2):71-75.
57. Halbreich U, Kahn LS. Role of estrogen in the aetiology and treatment of mood disorders. CNS Drugs. 2001;15(10): 797-817.
58. Rubino-Watkins MF, Doster JA, Franks S, et al. Oral contraceptive use: Implications for cognitive and emotional functioning. J Nerv Ment Dis. 1999;187(5): 275-280.
59. Oinonen KA, Mazmanian D. To what extent do oral contraceptives influence mood and affect J Affect Disord. 2002;70(3):229-240.
60. Freeman EW, Kroll R, Rapkin A, et al. Evaluation of a unique oral contraceptive in the treatment of premenstrual dysphoric disorder. J Womens Health Gend Based Med. 2001; 10(6):561-569.
61. Freeman MP. Depression and hormonal contraception. JAMA. 2001;286(6):671-672.
62. Felthous AR, Robinson DB, Conroy RW. Prevention of recurrent menstrual psychosis by an oral contraceptive. Am J Psychiatry. 1980;137(2):245-246.
63. Joffe H, Petrillo LF, Viguera AC, et al. Treatment of premenstrual worsening of depression with adjunctive oral contraceptive pills: A preliminary report. J Clin Psychiatry. 2007;68(12):1954-1962.
64. McEwen BS, Akama KT, Spencer-Segal JL, et al. Estrogen effects on the brain: Actions beyond the hypothalamus via novel mechanisms. Behav Neurosci. 2012;126(1):4-16.
65. Kirschbaum C, Kudelka BM, Gaab J, et al. Impact of gender, menstrual cycle phase, and oral contraceptives on the activity of the hypothalamus- pituitary-adrenal axis. Psychosom Med. 1999;61(2):154.
66. Westhoff CL, Petrie KA, Cremers S. Using changes in binding globulins to assess oral contraceptive compliance. Contraception. 2012;87(2):176-181.
67. Baca-Garcia E, Diaz-Sastre C, Ceverino A, et al. Suicide attempts among women during low estradiol/low progesterone states. J Psychiatr Res. 2010;44(4):209-214.
68. Sein Anand J, Chodorowski Z, Ciechanowicz R, et al. The relationship between suicidal attempts and menstrual cycle in women. Przeglad Lekarski. 2005;62(6):431-433.
69. Gemzell-Danielsson K, Cho S, Inki P, et al. Use of contraceptive methods and contraceptive recommendations among health care providers actively involved in contraceptive counseling - results of an international survey in 10 countries. Contraception. 2012;86(6):631-638.
70. Ustün TB, Ayuso-Mateos JL, Chatterji S, et al. Global burden of depressive disorders in the year 2000. Br J Psychiatry. 2004;184:386-392.