-
1
-
-
84888166435
-
Macitentan for the treatment of idiopathic pulmonary fibrosis: The randomised controlled MUSIC trial
-
Raghu G, Million-Rousseau R, Morganti A, et al. Macitentan for the treatment of idiopathic pulmonary fibrosis: the randomised controlled MUSIC trial. Eur Respir J 2013; 42: 1622-1632.
-
(2013)
Eur Respir J
, vol.42
, pp. 1622-1632
-
-
Raghu, G.1
Million-Rousseau, R.2
Morganti, A.3
-
2
-
-
84877297353
-
Treatment of idiopathic pulmonary fibrosis with ambrisentan: A parallel, randomized trial
-
Raghu G, Behr J, Brown KK, et al. Treatment of idiopathic pulmonary fibrosis with ambrisentan: a parallel, randomized trial. Ann Intern Med 2013; 158: 641-649.
-
(2013)
Ann Intern Med
, vol.158
, pp. 641-649
-
-
Raghu, G.1
Behr, J.2
Brown, K.K.3
-
3
-
-
75149172006
-
Quality of life and dyspnoea in patients treated with bosentan for idiopathic pulmonary fibrosis (BUILD-1)
-
Raghu G, King TE Jr, Behr J, et al. Quality of life and dyspnoea in patients treated with bosentan for idiopathic pulmonary fibrosis (BUILD-1). Eur Respir J 2010; 35: 118-123.
-
(2010)
Eur Respir J
, vol.35
, pp. 118-123
-
-
Raghu, G.1
King Jr., T.E.2
Behr, J.3
-
4
-
-
80051566676
-
BUILD-3: A randomized, controlled trial of bosentan in idiopathic pulmonary fibrosis
-
King TE Jr, Brown KK, Raghu G, et al. BUILD-3: a randomized, controlled trial of bosentan in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2011; 184: 92-99.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, pp. 92-99
-
-
King Jr., T.E.1
Brown, K.K.2
Raghu, G.3
-
5
-
-
37849012578
-
BUILD-1: A randomized placebo-controlled trial of bosentan in idiopathic pulmonary fibrosis
-
King TE Jr, Behr J, Brown KK, et al. BUILD-1: a randomized placebo-controlled trial of bosentan in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2008; 177: 75-81.
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 75-81
-
-
King Jr., T.E.1
Behr, J.2
Brown, K.K.3
-
6
-
-
79956341531
-
Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): Two randomised trials
-
Noble PW, Albera C, Bradford WZ, et al. Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials. Lancet 2011; 377: 1760-1769.
-
(2011)
Lancet
, vol.377
, pp. 1760-1769
-
-
Noble, P.W.1
Albera, C.2
Bradford, W.Z.3
-
7
-
-
80053091084
-
Efficacy of a tyrosine kinase inhibitor in idiopathic pulmonary fibrosis
-
Richeldi L, Costabel U, Selman M, et al. Efficacy of a tyrosine kinase inhibitor in idiopathic pulmonary fibrosis. N Engl J Med 2011; 365: 1079-1087.
-
(2011)
N Engl J Med
, vol.365
, pp. 1079-1087
-
-
Richeldi, L.1
Costabel, U.2
Selman, M.3
-
8
-
-
0345824715
-
A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis
-
Raghu G, Brown KK, Bradford WZ, et al. A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis. N Engl J Med 2004; 350: 125-133.
-
(2004)
N Engl J Med
, vol.350
, pp. 125-133
-
-
Raghu, G.1
Brown, K.K.2
Bradford, W.Z.3
-
9
-
-
79952717349
-
An official ATS/ERS/JRS/ALAT statement: Idiopathic pulmonary fibrosis: Evidence-based guidelines for diagnosis and management
-
Raghu G, Collard HR, Egan JJ, et al. An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management. Am J Respir Crit Care Med 2011; 183: 788-824.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 788-824
-
-
Raghu, G.1
Collard, H.R.2
Egan, J.J.3
-
10
-
-
34248372493
-
Idiopathic interstitial pneumonia: Do community and academic physicians agree on diagnosis?
-
Flaherty KR, Andrei AC, King TE Jr, et al. Idiopathic interstitial pneumonia: do community and academic physicians agree on diagnosis? Am J Respir Crit Care Med 2007; 175: 1054-1060.
-
(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 1054-1060
-
-
Flaherty, K.R.1
Andrei, A.C.2
King Jr., T.E.3
-
11
-
-
80053391874
-
Delayed access and survival in idiopathic pulmonary fibrosis: A cohort study
-
Lamas DJ, Kawut SM, Bagiella E, et al. Delayed access and survival in idiopathic pulmonary fibrosis: a cohort study. Am J Respir Crit Care Med 2011; 184: 842-847.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, pp. 842-847
-
-
Lamas, D.J.1
Kawut, S.M.2
Bagiella, E.3
-
12
-
-
84865112235
-
Idiopathic pulmonary fibrosis: Lung function is a clinically meaningful endpoint for phase III trials
-
du Bois RM, Nathan SD, Richeldi L, et al. Idiopathic pulmonary fibrosis: lung function is a clinically meaningful endpoint for phase III trials. Am J Respir Crit Care Med 2012; 186: 712-715.
-
(2012)
Am J Respir Crit Care Med
, vol.186
, pp. 712-715
-
-
Du Bois, R.M.1
Nathan, S.D.2
Richeldi, L.3
-
13
-
-
84861382039
-
Idiopathic pulmonary fibrosis: Clinically meaningful primary endpoints in phase 3 clinical trials
-
Raghu G, Collard HR, Anstrom KJ, et al. Idiopathic pulmonary fibrosis: clinically meaningful primary endpoints in phase 3 clinical trials. Am J Respir Crit Care Med 2012; 185: 1044-1048.
-
(2012)
Am J Respir Crit Care Med
, vol.185
, pp. 1044-1048
-
-
Raghu, G.1
Collard, H.R.2
Anstrom, K.J.3
-
14
-
-
84875208959
-
Forced vital capacity as a primary end point in idiopathic pulmonary fibrosis treatment trials: Making a silk purse from a sow's ear
-
Wells AU. Forced vital capacity as a primary end point in idiopathic pulmonary fibrosis treatment trials: making a silk purse from a sow's ear. Thorax 2013; 68: 309-310.
-
(2013)
Thorax
, vol.68
, pp. 309-310
-
-
Wells, A.U.1
-
15
-
-
0030268577
-
Surrogate end points in clinical trials: Are we being misled?
-
Fleming TR, DeMets DL. Surrogate end points in clinical trials: are we being misled? Ann Intern Med 1996; 125: 605-613.
-
(1996)
Ann Intern Med
, vol.125
, pp. 605-613
-
-
Fleming, T.R.1
Demets, D.L.2
-
16
-
-
0024520844
-
Surrogate endpoints in clinical trials: Definition and operational criteria
-
Prentice RL. Surrogate endpoints in clinical trials: definition and operational criteria. Stat Med 1989; 8: 431-440.
-
(1989)
Stat Med
, vol.8
, pp. 431-440
-
-
Prentice, R.L.1
-
17
-
-
84863984607
-
Validation of 6-minute walk distance as a surrogate end point in pulmonary arterial hypertension trials
-
Gabler NB, French B, Strom BL, et al. Validation of 6-minute walk distance as a surrogate end point in pulmonary arterial hypertension trials. Circulation 2012; 126: 349-356.
-
(2012)
Circulation
, vol.126
, pp. 349-356
-
-
Gabler, N.B.1
French, B.2
Strom, B.L.3
-
18
-
-
77956425361
-
Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment
-
Barry-Hamilton V, Spangler R, Marshall D, et al. Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment. Nat Med 2010; 16: 1009-1017.
-
(2010)
Nat Med
, vol.16
, pp. 1009-1017
-
-
Barry-Hamilton, V.1
Spangler, R.2
Marshall, D.3
-
19
-
-
38049091636
-
The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak
-
Tager AM, LaCamera P, Shea BS, et al. The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak. Nat Med 2008; 14: 45-54.
-
(2008)
Nat Med
, vol.14
, pp. 45-54
-
-
Tager, A.M.1
Lacamera, P.2
Shea, B.S.3
-
20
-
-
84874609382
-
Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis
-
Zhou Y, Huang X, Hecker L, et al. Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis. J Clin Invest 2013; 123: 1096-1108.
-
(2013)
J Clin Invest
, vol.123
, pp. 1096-1108
-
-
Zhou, Y.1
Huang, X.2
Hecker, L.3
-
21
-
-
84874457770
-
Genomic responses in mouse models poorly mimic human inflammatory diseases
-
Seok J, Warren HS, Cuenca AG, et al. Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci USA 2013; 110: 3507-3512.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 3507-3512
-
-
Seok, J.1
Warren, H.S.2
Cuenca, A.G.3
-
22
-
-
84859514262
-
Secondary prevention of idiopathic pulmonary fibrosis: Catching the horse still in the barn
-
Lederer DJ. Secondary prevention of idiopathic pulmonary fibrosis: catching the horse still in the barn. Am J Respir Crit Care Med 2012; 185: 697-699.
-
(2012)
Am J Respir Crit Care Med
, vol.185
, pp. 697-699
-
-
Lederer, D.J.1
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