Structural insights into calmodulin/adenylyl cyclase 8 interaction

Analytical and Bioanalytical Chemistry

Volumn 405, Issue 29, 2013, Pages 9333-9342

  Herbst, Sabine ^a   Masada, Nana ^b   Pfennig, Sabrina ^a   Ihling, Christian H ^a   Cooper, Dermot M F ^b   Sinz, Andrea ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Adenylyl cyclase 8; Calmodulin; Chemical cross linking; Mass spectrometry

Indexed keywords

ADENYLYL CYCLASE; ANTIPARALLEL ORIENTATIONS; CHEMICAL CROSS-LINKING; INTEGRATED APPROACH; ISOTHERMAL TITRATION CALORIMETRY; MYOSIN LIGHT CHAIN KINASE; STRUCTURAL INFORMATION; STRUCTURAL INSIGHTS;

CALCIUM; CAMS; CROSSLINKING; EXPERIMENTS; MASS SPECTROMETRY; PEPTIDES;

CALMODULIN;

ADENYLATE CYCLASE; ADENYLYL CYCLASE 8; CALCIUM; CALMODULIN;

ANIMAL; ARTICLE; CATTLE; CHEMISTRY; GENETICS; METABOLISM; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; THERMODYNAMICS;

ADENYLATE CYCLASE; ANIMALS; CALCIUM; CALMODULIN; CATTLE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; THERMODYNAMICS;

EID: 84890042378     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-013-7358-3     Document Type: Article

References (36)

1. Kretsinger RH, Nockolds CE (1973) Carp muscle calcium-binding protein. II. Structure determination and general description. J Biol Chem 248:3313-3326
2. Ikura M, Ames JB (2006) Genetic polymorphism and protein conformational plasticity in the calmodulin superfamily: two ways to promote multifunctionality. Proc Natl Acad Sci U S A 103:1159-1164
3. Yap KL, Kim J, Truong K, Sherman M, Yuan T, Ikura M (2000) Calmodulin target database. J Struct Funct Genom 1:8-14
4. Babu YS, Sack JS, Greenhough TJ, Bugg CE, Means AR, Cook WJ (1985) Three-dimensional structure of calmodulin. Nature 315:37-40
5. 2+ binding to calmodulin. Methods Enzymol 102:135-143
6. 2+, pH and temperature. J Biochem 95:19-28
7. Defer N, Best-Belpomme M, Hanoune J (2000) Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase. Am J Physiol Ren Physiol 279:F400-F416
8. Krupinski J, Coussen F, Bakalyar HA, Tang WJ, Feinstein PG, Orth K, Slaughter C, Reed RR, Gilman AG (1989) Adenylyl cyclase amino acid sequence: possible channel- or transporter-like structure. Science 244:1558-1564
9. 2+-signaling pathways of adenylyl cyclases. Cold Spring Harb Perspect Biol 3:a004143
10. 2+/calmodulin of type 1 and 8 adenylyl cyclases support their different physiological roles. J Biol Chem 284:4451-4463
11. Masada N, Schaks S, Jackson SE, Sinz A, Cooper DM (2012) Distinct mechanisms of calmodulin binding and regulation of adenylyl cyclases 1 and 8. Biochemistry 51:7917-7929
12. Vorherr T, Knopfel L, Hofmann F, Mollner S, Pfeuffer T, Carafoli E (1993) The calmodulin binding domain of nitric oxide synthase and adenylyl cyclase. Biochemistry 32:6081-6088
13. Levin LR, Reed RR (1995) Identification of functional domains of adenylyl cyclase using in vivo chimeras. J Biol Chem 270:7573-7579
14. Gu C, Cooper DM (1999) Calmodulin-binding sites on adenylyl cyclase type VIII. J Biol Chem 274:8012-8021
15. 2+ stimulation of adenylyl cyclase type 8. J Biol Chem 281:17379-17389
16. 2+/calmodulin binding and autoinhibition. J Biol Chem 284:15573-15588
17. Sinz A (2006) Chemical cross-linking and mass spectrometry to map three-dimensional protein structures and protein-protein interactions. Mass Spectrom Rev 25:663-682
18. Sinz A (2010) Investigation of protein-protein interactions in living cells by chemical crosslinking and mass spectrometry. Anal Bioanal Chem 397:3433-3440
19. Back JW, de Jong L, Muijsers AO, de Koster CG (2003) Chemical cross-linking and mass spectrometry for protein structural modeling. J Mol Biol 331:303-313
20. Krauth F, Ihling CH, Ruttinger HH, Sinz A (2009) Heterobifunctional isotope-labeled amine-reactive photo-cross-linker for structural investigation of proteins by matrix-assisted laser desorption/ionization tandem time-of-flight and electrospray ionization LTQ-Orbitrap mass spectrometry. Rapid Commun Mass Spectrom 23:2811-2818
21. Schaks S, Maucher D, Ihling CH, Sinz A (2012) In: König S (ed) Investigation of a calmodulin/peptide complex by chemical cross-linking and high-resolution mass spectrometry, biomacromolecular mass spectrometry. Nova, New York
22. Götze M, Pettelkau J, Schaks S, Bosse K, Ihling CH, Krauth F, Fritzsche R, Kühn U, Sinz A (2012) StavroX - a software for analyzing crosslinked products in protein interaction studies. J Am Soc Mass Spectrom 23:76-87
23. 2+ and possible function in short-term synaptic plasticity. EMBO J 29:680-691
24. Ikura M, Clore GM, Gronenborn AM, Zhu G, Klee CB, Bax A (1992) Solution structure of a calmodulin-target peptide complex by multidimensional NMR. Science 256:632-638
25. Kuboniwa H, Tjandra N, Grzesiek S, Ren H, Klee CB, Bax A (1995) Solution structure of calcium-free calmodulin. Nat Struct Biol 2:768-776
26. Fallon JL, Quiocho FA (2003) A closed compact structure of native Ca(2+)-calmodulin. Structure 11:1303-1307
27. Duhovny D, Nussinov R, Wolfson HJ (2002) Efficient Unbound Docking of Rigid Molecules. Springer, Berlin
28. Kalkhof S, Sinz A (2008) Chances and pitfalls of chemical cross-linking with amine-reactive N-hydroxysuccinimide esters. Anal Bioanal Chem 392:305-312
29. Mädler S, Bich C, Touboul D, Zenobi R (2009) Chemical cross-linking with NHS esters: a systematic study on amino acid reactivities. J Mass Spectrom 44:694-706
30. Hermanson GT (2010) Bioconjugate techniques, 2nd edn. Academic, London
31. Dimova K, Kawabe H, Betz A, Brose N, Jahn O (2006) Characterization of the Munc13-calmodulin interaction by photoaffinity labeling. Biochim Biophys Acta 1763:1256-1265
32. Dimova K, Kalkhof S, Pottratz I, Ihling C, Rodriguez-Castaneda F, Liepold T, Griesinger C, Brose N, Sinz A, Jahn O (2009) Structural insights into the calmodulin-Munc13 interaction obtained by cross-linking and mass spectrometry. Biochemistry 48:5908-5921
33. Ulmer TS, Soelaiman S, Li S, Klee CB, Tang WJ, Bax A (2003) Calcium dependence of the interaction between calmodulin and anthrax edema factor. J Biol Chem 278:29261-29266
34. 2+/calmodulin. J Biol Chem 267:5346-5354
35. Stull JT, Kamm KE, Vandenboom R (2011) Myosin light chain kinase and the role of myosin light chain phosphorylation in skeletal muscle. Arch Biochem Biophys 510:120-128
36. O'Neil KT, DeGrado WF (1990) How calmodulin binds its targets: sequence independent recognition of amphiphilic alpha-helices. Trends Biochem Sci 15:59-64