Effects of icariin and genistein on peak bone mass in rats

Acta Academiae Medicinae Sinicae

Volumn 35, Issue 5, 2013, Pages 542-546

  Cheng, Kui ^a   Ge, Bao Feng ^a   Zhen, Ping ^a   Chen, Ke Ming ^a   Ma, Xiao Ni ^a   Zhou, Jian ^a   Song, Peng ^a   Ma, Hui Ping ^a  

^a LANZHOU GENERAL HOSPITAL   (China)

Author keywords

Bone microarchitecture; Bone mineral density; Bone quality; Genistein; Icariin

Indexed keywords

COLLAGEN TYPE 1; GENISTEIN; ICARIIN; OSTEOCALCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOMECHANICS; BODY WEIGHT; BONE DENSITY; BONE MASS; CONTROLLED STUDY; DRUG SCREENING; NONHUMAN; OSSIFICATION; OSTEOLYSIS; OSTEOPOROSIS; RAT;

ANIMALS; BONE AND BONES; BONE DENSITY; FEMALE; FLAVONOIDS; GENISTEIN; OSTEOPOROSIS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84890029336     PISSN: 1000503X     EISSN: None     Source Type: Journal    
DOI: 10.3881/j.issn.1000-503X.2013.05.011     Document Type: Article

References (11)

1. Okano T. Effects of essential trace elements on bone turnoverin relation to the osteoporosis [J]. Jpn J Clin Med, 1996, 54(1): 148.
2. Mardon J, Mathey J, Kati-Coulibaly S, et al. Influence of lifelong soy isoflavones consumption on bone mass in the rat [J]. Exp Biol Med, 2008, 233(2): 229-237. (Pubitemid 351231555)
3. Kaludjerovic J, Ward WE. Neonatal exposure to daidzein, genistein, or the combination modulates bone development in female CD-I mice [J]. J Nutr, 2009, 139(3): 467-473.
4. Bhargavan B, Singh D, Gautam AK, et al. Medicarpin, a legume phytoalexin, stimulates osteoblast differentiation and promotes peak bone mass achievement in rats: evidence for estrogen receptor β-mediated osteogenic action of medicarpin [J]. J Nutr Biochem, 2012, 23(1): 27-38.
5. Setchell KD, Lydeking-Olsen E. Dietary phytoestrogens and their effect on bone: evidence from in vitro and in vivo, human observational, and dietary intervention studies [J]. Am J Clin Nutr, 2003, 78(3): 593S-609S. (Pubitemid 40012554)
6. Ma HP, Ming LG, Ge BF, et al. Icariin is more potent than genistein in promoting osteoblast differentiation and mineralization in vitro [J]. J Cell Biochem, 2011, 112(3): 916-923.
7. Elmarakby AA, Ibrahim AS, Faulkner J, et al. Tyrosine kinase inhibitor, genistein, reduces renal inflammation and injury in streptozotocin-induced diabetic mice [J]. Vasce Pharmacol, 2011, 55(5): 149-156.
8. Martin TJ, Seeman E. Bone remodelling: its local regulation and the emergence of bone fragility [J]. Res Clin Endcrinol Metab, 2008, 22(5): 701-722.
9. Liu ZG, Zhang R, Li C, et al. The osteoprotective effect of Radix Dipsaci extract in ovariectomized rats [J]. J Ethnopharmacology, 2009, 123(1): 74-81.