Acute toxicity assessment of liquid samples with primary cultures of rainbow trout hepatocytes

Small-Scale Freshwater Toxicity Investigations: Volume 1 - Toxicity Test Methods

Volumn , Issue , 2005, Pages 453-472

  Gagné, François ^a  

^a ENVIRONMENT CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84889986093     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/1-4020-3120-3_15     Document Type: Chapter

References (13)

1. Babich, H. and Borenfreund, E. (1987) Cultured fish cells for the ecotoxicity testing of aquatic pollutants, Toxicity Assessment 2, 119-133.
2. Baksi, S.M. and Frazier, J.M. (1986) Isolated fish hepatocytes-model systems for toxicology research, Aquatic Toxicology 16, 229-256.
3. Brandao, J.C., Bechets, H.H.L., Van de Vyver, I.E. and Dierickx, P.J. (1992) Correlation between the in vitro cytotoxicity to cultured fathead minnow fish cells and fish lethality data for 50 chemicals, Chemosphere 25, 553-562.
4. Dierickx, P.J. and Van de Vyver, I.E. (1991) Correlation of the neutral red uptake inhibition assay of cultured fathead minnow fish cells with lethality tests, Bulletin of Environmental Contamination and Toxicology 46, 649-653.
5. Environment Canada (1990) Biological Test Method, Acute Lethality Test Method Using Rainbow Trout, Conservation and Protection, Environment Canada, Report No. SPE/1/RM/9.
6. Gagne, F. and Blaise, C. (1997) Evaluation of cell viability, mixed function oxidase activity, metallothionein induction, and genotoxicity in rainbow trout hepatocytes exposed to industrial effluents. II. Validation of the rainbow trout hepatocyte model for ecotoxicity testing of industrial wastewater, Environmental Toxicology and Water Quality 12, 304-314.
7. Gagne, F. and Blaise, C. (1998) Differences in the measurement of cytotoxicity of complex mixtures with rainbow trout hepatocytes and fibroblasts, Chemosphere 37, 753-769.
8. Gagne, F., Blaise, C., vanAggelen, G., Boivin, P., Chong-Kit, R., Jonczyk, E., Marion, M., Kennedy, S., Legault R. and Goudreault, J. (1999) Intercalibration study in the evaluation of toxicity with rainbow trout hepatocytes, Environmental Toxicology 14, 429-437.
9. Klauning, J.E., Ruch, R.J, and Goldblatt, P.J. (1985) Trout hepatocyte culture: Isolation and primary culture, In Vitro Cellular and Developmental Biology 21, 221-228.
10. Morgan, J. D., Jensen, J.O.T. and Iwama, G. K. (1992) Effects of salinity on aerobic metabolism and development of eggs and alevins of steelhead trout (Oncorhynchus mykiss) and fall chinook salmon (Oncorhynchus tshawytscha), Canadian Journal of Zoology 70, 1341-1346.
11. Rixon, R. (1995) Validation-now or never, Trends in Alternative Testing, Joseph F. Morgan Research Foundation, Winter/Spring, 1-4, Ottawa.
12. Seglen, P.O. (1979) Hepatocyte suspensions and cultures as tools in experimental carcinogenesis, Journal of Toxicological and Environmental Health 5, 551-560.
13. Wydoski, R. S., and Whitney, R. R. (1979) Inland fishes of Washington. The University of Washington Press, Seattle.