Yttrium-90 radioembolotherapy for hepatocellular cancer

Hepatocellular Carcinoma: Targeted Therapy and Multidisciplinary Care

Volumn , Issue , 2011, Pages 319-335

  Murthy, Ravi ^a   Mutha, Pritesh ^a   Gupta, Sanjay ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Hepatocellular cancer; Yttrium 90

Indexed keywords

EID: 84889981146     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-60327-522-4_20     Document Type: Chapter

References (58)

1. Jemal A, Siegel R, Ward E et al (2008) Cancer statistics, 2008. CA Cancer J Clin 58:71-96
2. El-Serag HB (2007) Epidemiology of hepatocellular carcinoma in USA. Hepatol Res 37(Suppl 2):S88-S94
3. Mazzaferro V, Regalia E, Doci R et al (1996) Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N Engl J Med 334:693-699
4. Dawson LA (2005) Hepatic arterial yttrium 90 microspheres: another treatment option for hepatocellular carcinoma. J Vasc Interv Radiol 16:161-164
5. Kloop CT, Alford TC, Bateman J, Berry GN, Winship T (1950) Fractionated Intraarterial cancer; chemotherapy with methyl bis amine hydrochloride; a preliminary report. Ann Surg 132:811-832
6. Muller JH, Rossier PH (1951) A new method for the treatment of cancer of the lung by means of artificial radioactivity. Act Radiol 35:449-468
7. Pochin EE CG, Cunningham RM, Hollman A, Hudswell F, Payne BR (1954) Localization of colloidal gold in the lungs. Proceedings of the Radioisotope Conference 1:30
8. Ya PM, Guzman T, Loken MK, Perry JF Jr (1961) Isotope localization with tagged microspheres. Surgery 49:644-650
9. Kim YS LaFave JW, MacLean LD (1962) The use of radiating microspheres in the treatment of experimental and human malignancy. Surgery 52:220-231
10. Blanchard RJ, Grotenhuis I, LaFave JW et al (1964) Treatment of experimental tumors: Utilization of radioactive microspheres. Arch Surg 89:406-410
11. Blanchard RJ, LaFave JW, Kim YS et al (1964) Treatment of patients with advanced cancer utilizing Y90 microspheres. Cancer 18:375-380
12. Ariel I, Pack G (1967) Treatment of inoperable cancer of the liver by intra-arterial radioactive isotopes and chemotherapy. Cancer 20:793-804
13. Grady E (1979) Internal radiation therapy of hepatic cancer. Dis Colon Rectum 22:371-375
14. Mantravadi R, Spigos D, Tan W, Felix E (1982) Intraarterial yttrium 90 in the treatment of hepatic malignancy. Radiology 142:783-786
15. Wollner I, Knutsen C, Smith P et al (1988) Effects of hepatic arterial yttrium 90 glass microspheres in dogs. Cancer 61:1336-1344
16. Yan ZP, Lin G, Zhao HY, Dong YH (1993) Yttrium-90 glass microspheres injected via the portal vein. An experimental study. Acta Radiol 34:395-398
17. Yan ZP, Lin G, Zhao HY, Dong YH (1993) An experimental study and clinical pilot trials on yttrium-90 glass microspheres through the hepatic artery for treatment of primary liver cancer. Cancer 72:3210-3215
18. Shen S, DeNardo GL, Yuan A, DeNardo DA, DeNardo SJ (1994) Planar gamma camera imaging and quantitation of yttrium-90 bremsstrahlung. J Nucl Med 35:1381-1389
19. Shen S, DeNardo GL, DeNardo SJ (1994) Quantitative bremsstrahlung imaging of yttrium-90 using a Wiener filter. Med Phys 21:1409-1417
20. Stabin MG, Eckerman KF, Ryman JC, Williams LE (1994) Bremsstrahlung radiation dose in yttrium-90 therapy applications. J Nucl Med 35:1377-1380
21. Shepherd F, Rotstein L, Houle S, Yip T, Paul K, Sniderman K (1992) A phase I dose escalation trial of yttrium-90 microspheres in the treatment of primary hepatocellular carcinoma. Cancer 70:2250-2254
22. Andrews J, Walker S, Ackermann R, Cotton L, Ensminger W, Shapiro B (1994) Hepatic radioembolization with yttrium-90 containing glass microspheres: preliminary results and clinical follow-up. J Nucl Med 35:1637-1644
23. Murthy R, Nunez R, Szklaruk J et al (2005) Yttrium-90 microsphere therapy for hepatic malignancy: devices, indications, technical considerations, and potential complications. Radiographics 25(Suppl 1):S41-S55
24. Kennedy A, Nag S, Salem R et al (2007) Recommendations for radioembolization of hepatic malignancies using yttrium-90 microsphere brachytherapy: a consensus panel report from the radioembolization brachytherapy oncology consortium. Int J Radiat Oncol Biol Phys 68: 13-23
25. Liu DM, Salem R, Bui JT et al (2005) Angiographic considerations in patients undergoing liver-directed therapy. J Vasc Interv Radiol 16:911-935
26. Murthy R, Brown DB, Salem R et al (2007) Gastrointestinal complications associated with hepatic arterial Yttrium-90 microsphere therapy. J Vasc Interv Radiol 18:553-561; quiz 562
27. Sato K, Lewandowski RJ, Bui JT et al (2006) Treatment of unresectable primary and metastatic liver cancer with yttrium-90 microspheres (TheraSphere): assessment of hepatic arterial embolization. Cardiovasc Intervent Radiol 29:522-529
28. Murthy R, Xiong H, Nunez R, et al (2005) Yttrium 90 resin microspheres for the treatment of unresectable colorectal hepatic metastases after failure of multiple chemotherapy regimens: preliminary results. J Vasc Interv Radiol 16:937-945
29. Leung T, Lau W, Ho S et al (1995) Radiation pneumonitis after selective internal radiation treatment with intraarterial 90yttrium-microspheres for inoperable hepatic tumors. Int J Radiat Oncol Biol Phys 33:919-924
30. Salem R, Parikh P, Atassi B et al (2008) Incidence of radiation pneumonitis after hepatic intra-arterial radiotherapy with yttrium-90 microspheres assuming uniform lung distribution. Am J Clin Oncol 31:431-438
31. Murthy R, Kennedy A, Line B, Lund G, Stainken B, Van Echo D (2002) Augmentation of hep-atopulmonary shunting following trans-arterial hepatic brachytherapy (TAHB) with yttrium 90 25micron spheres: therasphere-Therapeutic implications. Radiology 225:307
32. Kamel IR, Reyes DK, Liapi E, Bluemke DA, Geschwind JF (2007) Functional MR imaging assessment of tumor response after 90Y microsphere treatment in patients with unresectable hepatocellular carcinoma. J Vasc Interv Radiol 18:49-56
33. Keppke AL, Salem R, Reddy D et al (2007) Imaging of hepatocellular carcinoma after treatment with yttrium-90 microspheres. AJR Am J Roentgenol 188:768-775
34. Salem R, Lewandowski R, Atassi B et al (2005) Treatment of unresectable hepatocellular carcinoma with use of 90Y microspheres (TheraSphere): safety, tumor response, and survival. J Vasc Interv Radiol 16:1627-1639
35. Kennedy A, Nutting C, Coldwell D, Gaiser J, Drachenberg C (2004) Pathologic response and microdosimetry of (90)Y microspheres in man: review of four explanted whole livers. Int J Radiat Oncol Biol Phys 60:1552-1563
36. Riaz A, Kulik L, Lewandowski RJ et al (2009) Radiologic-pathologic correlation of hepato-cellular carcinoma treated with internal radiation using yttrium-90 microspheres. Hepatology 49:1185-1193
37. Goin J, Dancey JE, Roberts C et al (2004) Comparison of post-embolization syndrome in the treatment of patients with unresectable hepatocellular carcinoma: Trans-catheter arterial chemo-embolization versus yttrium-90 glass microspheres. World J Nucl Med 3:49-56
38. Gulec SA, Mesoloras G, Dezarn WA, McNeillie P, Kennedy AS (2007) Safety and efficacy of Y-90 microsphere treatment in patients with primary and metastatic liver cancer: The tumor selectivity of the treatment as a function of tumor to liver flow ratio. J Transl Med 5:15
39. Young JY, Rhee TK, Atassi B et al (2007) Radiation dose limits and liver toxicities resulting from multiple yttrium-90 radioembolization treatments for hepatocellular carcinoma. J Vasc Interv Radiol 18:1375-1382
40. Goin J, Salem R, Carr B et al (2005) Treatment of unresectable hepatocellular carcinoma with intrahepatic yttrium 90 microspheres: factors associated with liver toxicities. J Vasc Interv Radiol 16:205-213
41. 90Yttrium glass microspheres (Therasphere) for unresectable hepatocellular carcinoma: interim safety and survival data on 65 patients. Liver Transpl 10:S107-S110
42. Atassi B, Bangash AK, Lewandowski RJ et al (2008) Biliary sequelae following radioem-bolization with Yttrium-90 microspheres. J Vasc Interv Radiol 19:691-697
43. Ng SS, Yu SC, Lai PB, Lau WY (2008) Biliary complications associated with selective internal radiation (SIR) therapy for unresectable liver malignancies. Dig Dis Sci 53:2813-2817
44. Dancey J, Shepherd F, Paul K et al (2000) Treatment of nonresectable hepatocellular carcinoma with intrahepatic 90Y-microspheres. J Nucl Med 41:1673-1681
45. Lau W, Leung W, Ho S et al (1994) Treatment of inoperable hepatocellular carcinoma with intrahepatic arterial yttrium-90 microspheres: a phase I and II study. Br J Cancer 70:994-999
46. Lau W, Ho S, Leung W, Chan M, Lee W, Johnson P (2001) What determines survival duration in hepatocellular carcinoma treated with intraarterial Yttrium-90 microspheres? Hepatogastroenterology 48:338-340
47. Geschwind J, Salem R, Carr B et al (2004) Yttrium-90 microspheres for the treatment of hepatocellular carcinoma. Gastroenterology 127:S194-S205
48. Liu MD, Uaje MB, Al-Ghazi MS et al (2004) Use of yttrium-90 TheraSphere for the treatment of unresectable hepatocellular carcinoma. Am Surg 70:947-953
49. Salem R, Lewandowski R, Roberts C et al (2004) Use of yttrium-90 glass microspheres (TheraSphere) for the treatment of unresectable hepatocellular carcinoma in patients with portal vein thrombosis. J Vasc Interv Radiol 15:335-345
50. Kulik LM, Carr BI, Mulcahy MF et al (2008) Safety and efficacy of 90Y radiotherapy for hepatocellular carcinoma with and without portal vein thrombosis. Hepatology 47:71-81
51. Sangro B, Bilbao JI, Boan J et al (2006) Radioembolization using 90Y-resin microspheres for patients with advanced hepatocellular carcinoma. Int J Radiat Oncol Biol Phys 66:792-800
52. Ertle J, Antoch G, Hamami M, Bockisch A, Ferken G, Hilgard P (2008) Radioembolization with therasphere yttrium-90 glass microspheres for advanced hepatocellular carcinoma: a European pilot phase II study. Presented at the Second Annual Meeting of the International Liver Cancer Association, Chicago, IL, September 2008, O-035
53. Romito R, Mazzaferro V, Spreafico C et al (2008) Intra-hepatic arterial radioembolization with 90Y-glass microspheres for hepatocellular carcinoma with macrovascular invasion: preliminary results. Presented at the Second Annual Meeting of the International Liver Cancer Association (ILCA), Chicago, IL, September 2008, p 142
54. Iñarrairaegui M, Thurston KG, Martinez-Cuesta A et al (2008) Radioembolization of hep-atocellular carcinoma in patients presenting with portal vein occlusion: a safety analysis. Presented at the Second Annual Meeting of the International Liver Cancer Association (ILCA), Chicago, IL, September 2008, p 140
55. D'Avola DD, Iñarrairaegui M, Bilbao JI et al (2008) Extended survival in patients with unre-sectable advanced hepatocellular carcinoma treated using radioembolization. Presented at the Second Annual Meeting of the International Liver Cancer Association (ILCA), Chicago, IL, September 2008, p 139
56. Carpanese LPG, Vallati G et al (2008) Selective internal radiation therapy 90Y (SIRT) in multifocal HCC: clinical preliminary results in one year follow-up. World Conference on Interventional Oncology 2008, Poster P69
57. Rhee T, Omary R, Gates V et al (2005) The effect of catheter-directed CT angiography on yttrium-90 radioembolization treatment of hepatocellular carcinoma. J Vasc Interv Radiol 16:1085-1091
58. Kulik LM, Atassi B, van Holsbeeck L et al (2006) Yttrium-90 microspheres (TheraSphere) treatment of unresectable hepatocellular carcinoma: downstaging to resection, RFA and bridge to transplantation. J Surg Oncol 94:572-586