The role of postoperative prophylactic antibiotics in the treatment of facial fractures: A randomized, double-blind, placebo-controlled pilot clinical study. Part 2: Mandibular fractures in 59 patients

British Journal of Oral and Maxillofacial Surgery

Volumn 51, Issue 8, 2013, Pages 803-807

  Schaller, Benoit ^a   Soong, Poh Luon ^a,b   Zix, Jürgen ^a   Iizuka, Tateyuki ^a   Lieger, Olivier ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b National Dental Centre of Singapore   (Singapore)

Author keywords

Adverse drug event; Antibiotic; Antimicrobial agents; Infection; Mandible fractures

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; PLACEBO; POVIDONE IODINE; TOPICAL ANTIINFECTIVE AGENT;

ADULT; ALVEOLAR BONE; ANTIBIOTIC PROPHYLAXIS; ARTICLE; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; FOLLOW UP; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MANDIBLE FRACTURE; PILOT STUDY; POSTOPERATIVE INFECTION; POSTOPERATIVE PERIOD; RANDOMIZED CONTROLLED TRIAL; RASH; SWELLING; WOUND INFECTION; ADOLESCENT; AGED; COMPARATIVE STUDY; DEVICES; DRAINAGE; EXANTHEMA; INTRAVENOUS DRUG ADMINISTRATION; JAW; MANDIBULAR FRACTURES; MIDDLE AGED; ORAL DRUG ADMINISTRATION; OSTEOSYNTHESIS; POSTOPERATIVE CARE; PROCEDURES; PROSPECTIVE STUDY; SURGICAL WOUND DEHISCENCE; SURGICAL WOUND INFECTION; YOUNG ADULT;

ADMINISTRATION, INTRAVENOUS; ADMINISTRATION, ORAL; ADOLESCENT; ADULT; AGED; ALVEOLAR PROCESS; AMOXICILLIN-POTASSIUM CLAVULANATE COMBINATION; ANTI-INFECTIVE AGENTS, LOCAL; ANTIBIOTIC PROPHYLAXIS; DOUBLE-BLIND METHOD; DRAINAGE; EXANTHEMA; FEMALE; FOLLOW-UP STUDIES; FRACTURE FIXATION, INTERNAL; HUMANS; MALE; MANDIBULAR FRACTURES; MIDDLE AGED; PILOT PROJECTS; PLACEBOS; POSTOPERATIVE CARE; POVIDONE-IODINE; PROSPECTIVE STUDIES; SURGICAL WOUND DEHISCENCE; SURGICAL WOUND INFECTION; YOUNG ADULT;

EID: 84889884228     PISSN: 02664356     EISSN: 15321940     Source Type: Journal    
DOI: 10.1016/j.bjoms.2013.08.008     Document Type: Article

References (23)

1. B.O. Ogundare, A. Bonnick, and N. Bayley Pattern of mandibular fractures in an urban major trauma center J Oral Maxillofac Surg 61 2003 713 718
2. R.H. Haug, J. Prather, and A.T. Indresano An epidemiologic survey of facial fractures and concomitant injuries J Oral Maxillofac Surg 48 1990 926 932
3. E.H. Schaefer, and E.J. Caterson IV Antibiotic selection for open reduction internal fixation of mandible fractures J Craniofac Surg 24 2013 85 88
4. R.A. Chole, and J. Yee Antibiotic prophylaxis for facial fractures. A prospective, randomized clinical trial Arch Otolaryngol Head Neck Surg 113 1987 1055 1057
5. R.D. Zallen, and J.T. Curry A study of antibiotic usage in compound mandibular fractures J Oral Surg 33 1975 431 434
6. G. Hotz, J. Novotny-Lenhard, M. Kinzig, and F. Soergel Single-dose antibiotic prophylaxis in maxillofacial surgery Chemotherapy 40 1994 65 69
7. H.A. Merten, and F. Halling Perioperative antibiotic prophylaxis in maxillofacial surgery (in German) Infection 21 suppl. 1 1993 s45 s48
8. D.J. Courtney, S. Thomas, and P.H. Whitfield Isolated orbital blowout fractures: survey and review Br J Oral Maxillofac Surg 38 2000 496 504
9. L. Folkestad, and G. Granström A prospective study of orbital fracture sequelae after change of surgical routines J Oral Maxillofac Surg 61 2003 1038 1044
10. K.L. Gerlach, and H.D. Pape Studies on preventive antibiotics in the surgical treatment of mandibular fractures (in German) Dtsch Z Mund Kiefer Gesichtschir 12 1988 497 500
11. KDOQI Clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification Am J Kidney Dis 39 suppl 1 2002 S1 S266
12. A.J. Mangram, T.C. Horan, M.L. Pearson, L.C. Silver, and W.R. Jarvis Guideline for prevention of surgical site infection, 1999. Centres for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee Am J Infect Control 27 1999 97 134
13. J. Lamphier, V. Ziccardi, A. Ruvo, and M. Janel Complications of mandibular fractures in an urban teaching center J Oral Maxillofac Surg 61 2003 745 750
14. E. Ellis III Outcomes of patients with teeth in the line of mandibular angle fractures treated with stable internal fixation J Oral Maxillofac Surg 60 2002 863 866
15. T. Iizuka, C. Lindqvist, D. Hallikainen, and P. Paukku Infection after rigid internal fixation of mandibular fractures: a clinical and radiologic study J Oral Maxillofac Surg 49 1991 585 593
16. D.K. Dhariwal, A.J. Gibbons, M. Murphy, J. Llewelyn, and M.C. Gregory A two year review of the treatment and complications of mandibular angle fractures J R Army Med Corps 148 2002 115 117
17. J. Potter, and E. Ellis III Treatment of mandibular angle fractures with a malleable noncompression miniplate J Oral Maxillofac Surg 57 1999 288 293
18. I.E. Stone, T.B. Dodson, and R.A. Bays Risk factors for infection following operative treatment of mandibular fractures: a multivariate analysis Plast Reconstr Surg 91 1993 64 68
19. P. Scolozzi, and M. Richter Treatment of severe mandibular fractures using AO reconstruction plates J Oral Maxillofac Surg 61 2003 458 461
20. T. Iizuka, and C. Lindqvist Rigid internal fixation of fractures in the angular region of the mandible: an analysis of factors contributing to different complications Plast Reconstr Surg 91 1993 265 273
21. A.O. Abubaker, and M.K. Rollert Postoperative antibiotic prophylaxis in mandibular fractures: a preliminary randomized, double-blind, and placebo-controlled clinical study J Oral Maxillofac Surg 59 2001 1415 1419
22. B.A. Miles, J.K. Potter, and E. Ellis 3rd The efficacy of postoperative antibiotic regimens in the open treatment of mandibular fractures: a prospective randomized trial J Oral Maxillofac Surg 64 2006 576 582
23. R.B. James, C. Fredrickson, and J.N. Kent Prospective study of mandibular fractures J Oral Surg 39 1981 275 281