Accumulation of serum lipids by vascular smooth muscle cells involves a macropinocytosis-like uptake pathway and is associated with the downregulation of the ATP-binding cassette transporter A1

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 386, Issue 12, 2013, Pages 1081-1093

  Rivera, Jennifer ^a,b   Walduck, Anna K ^b   Thomas, Shane R ^c   Glaros, Elias N ^c   Hooker, Elizabeth U ^a   Guida, Elizabeth ^a   Sobey, Christopher G ^a   Drummond, Grant R ^a  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

ATP binding cassette transporter A1; Foam cells; Macropinocytosis; Serum lipids; Vascular smooth muscle cells

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ABC TRANSPORTER A1; CHOLESTEROL; CYTOCHALASIN D; DANSYLCADAVERINE; LIPID; PLATELET DERIVED GROWTH FACTOR; SCAVENGER RECEPTOR; STRESS ACTIVATED PROTEIN KINASE;

ACTIN POLYMERIZATION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTERY INTIMA; ARTICLE; ATHEROSCLEROTIC PLAQUE; CHLAMYDOPHILA PNEUMONIAE; DOWN REGULATION; ENDOCYTOSIS; ENZYME INHIBITION; FOAM CELL; HYPERCHOLESTEROLEMIA; LIPID BLOOD LEVEL; LIPID STORAGE; LIPID TRANSPORT; MALE; MOUSE; MUSCLE CELL; NONHUMAN; PINOCYTOSIS; VASCULAR SMOOTH MUSCLE;

ACTINS; ANIMALS; APOLIPOPROTEINS E; ATP BINDING CASSETTE TRANSPORTER 1; BIOLOGICAL MARKERS; CELL LINE; DISEASE MODELS, ANIMAL; DOWN-REGULATION; HYPERCHOLESTEROLEMIA; INFLAMMATION MEDIATORS; LIPIDS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PHOSPHATIDYLINOSITOL 3-KINASE; PINOCYTOSIS; PROTEIN KINASE INHIBITORS; TIME FACTORS;

EID: 84889879533     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-013-0909-5     Document Type: Article

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