Motor skill learning induces changes in white matter microstructure and myelination

Journal of Neuroscience

Volumn 33, Issue 50, 2013, Pages 19499-19503

  Sampaio Baptista, Cassandra ^a   Khrapitchev, Alexandre A ^c   Foxley, Sean ^a   Schlagheck, Theresa ^a   Scholz, Jan ^a,e   Jbabdi, Saad ^a   DeLuca, Gabriele C ^a   Miller, Karla L ^a   Taylor, Amy ^b   Thomas, Nagheme ^d   Kleim, Jeffrey ^d   Sibson, Nicola R ^c   Bannerman, David ^b   Johansen Berg, Heidi ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d Arizona State University   (United States)

^e HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

MYELIN; MYELIN BASIC PROTEIN;

ANIMAL TISSUE; ARTICLE; BEHAVIOR; CONTROLLED STUDY; DIFFUSION TENSOR IMAGING; DIFFUSION WEIGHTED IMAGING; FRACTIONAL ANISOTROPY; HISTOLOGY; IMMUNOHISTOCHEMISTRY; LEARNING; MALE; MOTOR PERFORMANCE; MYELINATION; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORIMOTOR CORTEX; SENSORIMOTOR FUNCTION; WHITE MATTER;

ANIMALS; ANISOTROPY; DIFFUSION MAGNETIC RESONANCE IMAGING; LEARNING; MALE; MOTOR CORTEX; MYELIN SHEATH; NERVE FIBERS, MYELINATED; NEURONAL PLASTICITY; PSYCHOMOTOR PERFORMANCE; RATS;

EID: 84889782015     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3048-13.2013     Document Type: Article

References (21)

1. Beaulieu C (2002) The basis of anisotropic water diffusion in the nervous system: a technical review. NMR Biomed 15:435-455. CrossRef Medline
2. Blumenfeld-Katzir T, Pasternak O, Dagan M, Assaf Y (2011) Diffusion MRI of structural brain plasticity induced by a learning and memory task. PLoS One 6:e20678. CrossRef Medline
3. Dayan E, Cohen LG (2011) Neuroplasticity subserving motor skill learning. Neuron 72:443-454. CrossRef Medline
4. Demerens C, Stankoff B, Logak M, Anglade P, Allinquant B, Couraud F, Zalc B, Lubetzki C (1996) Induction of myelination in the central nervous system by electrical activity. Proc Natl Acad Sci U S A 93:9887-9892. CrossRef Medline
5. Draganski B, Gaser C, Busch V, Schuierer G, Bogdahn U, May A (2004) Neuroplasticity: changes in grey matter induced by training. Nature 427: 311-312. CrossRef Medline
6. Fields RD (2008) White matter in learning, cognition and psychiatric disorders. Trends Neurosci 31:361-370. CrossRef Medline
7. Gould E, Beylin A, Tanapat P, Reeves A, Shors TJ (1999) Learning enhances adult neurogenesis in the hippocampal formation. Nat Neurosci 2:260-265. CrossRef Medline
8. Kleim JA, Barbay S, Cooper NR, Hogg TM, Reidel CN, Remple MS, Nudo RJ (2002) Motor learning-dependent synaptogenesis is localized to functionally reorganized motor cortex. Neurobiol Learn Mem 77:63-77. CrossRef Medline
9. Kleim JA, Hogg TM, VandenBerg PM, Cooper NR, Bruneau R, Remple M (2004) Cortical synaptogenesis and motor map reorganization occur during late, but not early, phase of motor skill learning. J Neurosci 24: 628-633. CrossRef Medline
10. Kleim JA, Barbay S, Nudo RJ (1998) Functional reorganization of the rat motor cortex following motor skill learning. J Neurophysiol 80:3321-3325. Medline
11. Kolasinski J, Stagg CJ, Chance SA, Deluca GC, Esiri MM, Chang EH, Palace JA, McNab JA, Jenkinson M, Miller KL, Johansen-Berg H (2012) A combined post-mortem magnetic resonance imaging and quantitative histological study of multiple sclerosis pathology. Brain 135:2938-2951. CrossRef Medline
12. Markham JA, Herting MM, Luszpak AE, Juraska JM, GreenoughWT (2009) Myelination of the corpus callosum in male and female rats following complex environment housing during adulthood. Brain Res 1288:9-17. CrossRef Medline
13. Martini R, Schachner M (1997) Molecular bases of myelin formation as revealed by investigations on mice deficient in glial cell surface molecules. Glia 19:298-310. CrossRef Medline
14. Paxinos G, Watson C (2007) The rat brain in stereotaxic coordinates, 6th Ed. Amsterdam: Academic/Elsevier.
15. Scholz J (2010) Structural brain plasticity: Individual differences and changes with learning. PhD thesis, University of Oxford.
16. Scholz J, Klein MC, Behrens TE, Johansen-Berg H (2009) Training induces changes in white-matter architecture. Nat Neurosci 12:1370-1371. CrossRef Medline
17. Serrien DJ, Brown P (2003) The integration of cortical and behavioural dynamics during initial learning of a motor task. Eur J Neurosci 17:1098-1104. CrossRef Medline
18. Smith SM, Jenkinson M, Johansen-Berg H, Rueckert D, Nichols TE, Mackay CE, Watkins KE, Ciccarelli O, Cader MZ, Matthews PM, Behrens TE (2006) Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data. Neuroimage 31:1487-1505. CrossRef Medline
19. Xu T, Yu X, Perlik AJ, Tobin WF, Zweig JA, Tennant K, Jones T, Zuo Y (2009) Rapid formation and selective stabilization of synapses for enduring motor memories. Nature 462:915-919. CrossRef Medline
20. Zatorre RJ, Fields RD, Johansen-Berg H (2012) Plasticity in gray and white: neuroimaging changes in brain structure during learning. Nat Neurosci 15:528-536. CrossRef Medline
21. Zhao YY, Shi XY, Qiu X, Lu W, Yang S, Li C, Chen L, Zhang L, Cheng GH, Tang Y (2012) Enriched environment increases the myelinated nerve fibers of aged rat corpus callosum. Anat Rec (Hoboken) 295:999-1005. CrossRef Medline