-
1
-
-
70350004886
-
Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics
-
Gillings AS, Balmanno K, Wiggins CM, Johnson M, Cook SJ: Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics. FEBS J 2009; 276: 6050-6062.
-
(2009)
FEBS J
, vol.276
, pp. 6050-6062
-
-
Gillings, A.S.1
Balmanno, K.2
Wiggins, C.M.3
Johnson, M.4
Cook, S.J.5
-
2
-
-
84862777672
-
A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer
-
Ng KP, Hillmer AM, Chuah CT, Juan WC, Ko TK, Teo AS, Ariyaratne PN, Takahashi N, Sawada K, Fei Y, Soh S, Lee WH, Huang JW, Allen JC Jr, Woo XY, Nagarajan N, Kumar V, Thalamuthu A, Poh WT, Ang AL, Mya HT, How GF, Yang LY, Koh LP, Chowbay B, Chang CT, Nadarajan VS, Chng WJ, Than H, Lim LC, Goh YT, Zhang S, Poh D, Tan P, Seet JE, Ang MK, Chau NM, Ng QS, Tan DS, Soda M, Isobe K, Nothen MM, Wong TY, Shahab A, Ruan X, Cacheux-Rataboul V, Sung WK, Tan EH, Yatabe Y, Mano H, Soo RA, Chin TM, Lim WT, Ruan Y, Ong ST: A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer. Nat Med 2012; 18: 521-528.
-
(2012)
Nat Med
, vol.18
, pp. 521-528
-
-
Ng, K.P.1
Hillmer, A.M.2
Chuah, C.T.3
Juan, W.C.4
Ko, T.K.5
Teo, A.S.6
Ariyaratne, P.N.7
Takahashi, N.8
Sawada, K.9
Fei, Y.10
Soh, S.11
Lee, W.H.12
Huang, J.W.13
Allen, J.C.14
Woo, X.Y.15
Nagarajan, N.16
Kumar, V.17
Thalamuthu, A.18
Poh, W.T.19
Ang, A.L.20
Mya, H.T.21
How, G.F.22
Yang, L.Y.23
Koh, L.P.24
Chowbay, B.25
Chang, C.T.26
Nadarajan, V.S.27
Chng, W.J.28
Than, H.29
Lim, L.C.30
Goh, Y.T.31
Zhang, S.32
Poh, D.33
Tan, P.34
Seet, J.E.35
Ang, M.K.36
Chau, N.M.37
Ng, Q.S.38
Tan, D.S.39
Soda, M.40
Isobe, K.41
Nothen, M.M.42
Wong, T.Y.43
Shahab, A.44
Ruan, X.45
Cacheux-Rataboul, V.46
Sung, W.K.47
Tan, E.H.48
Yatabe, Y.49
Mano, H.50
Soo, R.A.51
Chin, T.M.52
Lim, W.T.53
Ruan, Y.54
Ong, S.T.55
more..
-
3
-
-
57749189578
-
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: A phase III randomised, double-blind, placebo-controlled trial
-
Cheng AL, Kang YK, Chen Z, Tsao CJ, Qin S, Kim JS, Luo R, Feng J, Ye S, Yang TS, Xu J, Sun Y, Liang H, Liu J, Wang J, Tak WY, Pan H, Burock K, Zou J, Voliotis D, Guan Z: Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol 2009; 10: 25-34.
-
(2009)
Lancet Oncol
, vol.10
, pp. 25-34
-
-
Cheng, A.L.1
Kang, Y.K.2
Chen, Z.3
Tsao, C.J.4
Qin, S.5
Kim, J.S.6
Luo, R.7
Feng, J.8
Ye, S.9
Yang, T.S.10
Xu, J.11
Sun, Y.12
Liang, H.13
Liu, J.14
Wang, J.15
Tak, W.Y.16
Pan, H.17
Burock, K.18
Zou, J.19
Voliotis, D.20
Guan, Z.21
more..
-
4
-
-
47949116252
-
Sorafenib in advanced hepatocellular carcinoma
-
Sharp Investigators Study Group
-
Llovet JM, Ricci S, Mazzaferro V, Hilgard P, Gane E, Blanc JF, de Oliveira AC, Santoro A, Raoul JL, Forner A, Schwartz M, Porta C, Zeuzem S, Bolondi L, Greten TF, Galle PR, Seitz JF, Borbath I, Haussinger D, Giannaris T, Shan M, Moscovici M, Voliotis D, Bruix J, Sharp Investigators Study Group: Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 2008; 359: 378-390.
-
(2008)
N Engl J Med
, vol.359
, pp. 378-390
-
-
Llovet, J.M.1
Ricci, S.2
Mazzaferro, V.3
Hilgard, P.4
Gane, E.5
Blanc, J.F.6
De Oliveira, A.C.7
Santoro, A.8
Raoul, J.L.9
Forner, A.10
Schwartz, M.11
Porta, C.12
Zeuzem, S.13
Bolondi, L.14
Greten, T.F.15
Galle, P.R.16
Seitz, J.F.17
Borbath, I.18
Haussinger, D.19
Giannaris, T.20
Shan, M.21
Moscovici, M.22
Voliotis, D.23
Bruix, J.24
more..
-
5
-
-
33749238553
-
Discovery and development of sorafenib: A multikinase inhibitor for treating cancer
-
Wilhelm S, Carter C, Lynch M, Lowinger T, Dumas J, Smith RA, Schwartz B, Simantov R, Kelley S: Discovery and development of sorafenib: a multikinase inhibitor for treating cancer. Nat Rev Drug Discov 2006; 5: 835-844.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 835-844
-
-
Wilhelm, S.1
Carter, C.2
Lynch, M.3
Lowinger, T.4
Dumas, J.5
Smith, R.A.6
Schwartz, B.7
Simantov, R.8
Kelley, S.9
-
6
-
-
84869080379
-
Prognosis of advanced hepatocellular carcinoma patients enrolled in clinical trials can be classified by current staging systems
-
Shao YY, Lu LC, Lin ZZ, Hsu C, Shen YC, Hsu CH, Cheng AL: Prognosis of advanced hepatocellular carcinoma patients enrolled in clinical trials can be classified by current staging systems. Br J Cancer 2012; 107: 1672-1677.
-
(2012)
Br J Cancer
, vol.107
, pp. 1672-1677
-
-
Shao, Y.Y.1
Lu, L.C.2
Lin, Z.Z.3
Hsu, C.4
Shen, Y.C.5
Hsu, C.H.6
Cheng, A.L.7
-
7
-
-
84859880607
-
Plasma biomarkers as predictors of outcome in patients with advanced hepatocellular carcinoma
-
Llovet JM, Pena CE, Lathia CD, Shan M, Meinhardt G, Bruix J: Plasma biomarkers as predictors of outcome in patients with advanced hepatocellular carcinoma. Clin Cancer Res 2012; 18: 2290-2300.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 2290-2300
-
-
Llovet, J.M.1
Pena, C.E.2
Lathia, C.D.3
Shan, M.4
Meinhardt, G.5
Bruix, J.6
-
8
-
-
77953124105
-
Phase II study of combining sorafenib with metronomic tegafur/ uracil for advanced hepatocellular carcinoma
-
Hsu CH, Shen YC, Lin ZZ, Chen PJ, Shao YY, Ding YH, Hsu C, Cheng AL: Phase II study of combining sorafenib with metronomic tegafur/ uracil for advanced hepatocellular carcinoma. J Hepatol 2010; 53: 126-131.
-
(2010)
J Hepatol
, vol.53
, pp. 126-131
-
-
Hsu, C.H.1
Shen, Y.C.2
Lin, Z.Z.3
Chen, P.J.4
Shao, Y.Y.5
Ding, Y.H.6
Hsu, C.7
Cheng, A.L.8
-
9
-
-
0025117392
-
Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome
-
Daley GQ, Van Etten RA, Baltimore D: Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome. Science 1990; 247: 824-830.
-
(1990)
Science
, vol.247
, pp. 824-830
-
-
Daley, G.Q.1
Van Etten, R.A.2
Baltimore, D.3
-
10
-
-
0025209916
-
Acute leukaemia in bcr/abl transgenic mice
-
Heisterkamp N, Jenster G, ten Hoeve J, Zovich D, Pattengale PK, Groffen J: Acute leukaemia in bcr/abl transgenic mice. Nature 1990; 344: 251-253.
-
(1990)
Nature
, vol.344
, pp. 251-253
-
-
Heisterkamp, N.1
Jenster, G.2
Ten Hoeve, J.3
Zovich, D.4
Pattengale, P.K.5
Groffen, J.6
-
11
-
-
50149108795
-
Induction of lung adenocarcinoma in transgenic mice expressing activated EGFR driven by the SP-C promoter
-
Ohashi K, Rai K, Fujiwara Y, Osawa M, Hirano S, Takata K, Kondo E, Yoshino T, Takata M, Tanimoto M, Kiura K: Induction of lung adenocarcinoma in transgenic mice expressing activated EGFR driven by the SP-C promoter. Cancer Sci 2008; 99: 1747-1753.
-
(2008)
Cancer Sci
, vol.99
, pp. 1747-1753
-
-
Ohashi, K.1
Rai, K.2
Fujiwara, Y.3
Osawa, M.4
Hirano, S.5
Takata, K.6
Kondo, E.7
Yoshino, T.8
Takata, M.9
Tanimoto, M.10
Kiura, K.11
-
12
-
-
84857002194
-
BIM expression in treatment-naive cancers predicts responsiveness to kinase inhibitors
-
Faber AC, Corcoran RB, Ebi H, Sequist LV, Waltman BA, Chung E, Incio J, Digumarthy SR, Pollack SF, Song Y, Muzikansky A, Lifshits E, Roberge S, Coffman EJ, Benes CH, Gomez HL, Baselga J, Arteaga CL, Rivera MN, Dias-Santagata D, Jain RK, Engelman JA: BIM expression in treatment-naive cancers predicts responsiveness to kinase inhibitors. Cancer Discov 2011; 1: 352-365.
-
(2011)
Cancer Discov
, vol.1
, pp. 352-365
-
-
Faber, A.C.1
Corcoran, R.B.2
Ebi, H.3
Sequist, L.V.4
Waltman, B.A.5
Chung, E.6
Incio, J.7
Digumarthy, S.R.8
Pollack, S.F.9
Song, Y.10
Muzikansky, A.11
Lifshits, E.12
Roberge, S.13
Coffman, E.J.14
Benes, C.H.15
Gomez, H.L.16
Baselga, J.17
Arteaga, C.L.18
Rivera, M.N.19
Dias-Santagata, D.20
Jain, R.K.21
Engelman, J.A.22
more..
-
13
-
-
33749017926
-
Phase II study of sorafenib in patients with advanced hepatocellular carcinoma
-
Abou-Alfa GK, Schwartz L, Ricci S, Amadori D, Santoro A, Figer A, De Greve J, Douillard JY, Lathia C, Schwartz B, Taylor I, Moscovici M, Saltz LB: Phase II study of sorafenib in patients with advanced hepatocellular carcinoma. J Clin Oncol 2006; 24: 4293-4300.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4293-4300
-
-
Abou-Alfa, G.K.1
Schwartz, L.2
Ricci, S.3
Amadori, D.4
Santoro, A.5
Figer, A.6
De Greve, J.7
Douillard, J.Y.8
Lathia, C.9
Schwartz, B.10
Taylor, I.11
Moscovici, M.12
Saltz, L.B.13
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