Regional expression of the BCRP/ABCG2 transporter in term human placentas

Reproductive Toxicology

Volumn 43, Issue , 2014, Pages 72-77

  Memon, Naureen ^a   Bircsak, Kristin M ^b   Archer, Faith ^a   Gibson, Christopher J ^b   Ohman Strickland, Pamela ^c   Weinberger, Barry I ^a   Parast, Mana M ^d   Vetrano, Anna M ^a   Aleksunes, Lauren M ^b,e  

^a ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c RUTGERS SCHOOL OF PUBLIC HEALTH   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e RUTGERS UNIVERSITY   (United States)

Author keywords

ABCG2; BCRP; Housekeeping gene; Placenta; Transporter

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; MESSENGER RNA;

18S GENE; ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; GAPDH GENE; GENE EXPRESSION; HOUSEKEEPING GENE; HUMAN; HUMAN TISSUE; MALE; NORMAL HUMAN; PLACENTA; PRL GENE; PROTEIN EXPRESSION; RPL13A GENE;

ABCG2; BCRP; HOUSEKEEPING GENE; PLACENTA; TRANSPORTER;

ADULT; ATP-BINDING CASSETTE TRANSPORTERS; FEMALE; HUMANS; NEOPLASM PROTEINS; PLACENTA; PREGNANCY; RNA, MESSENGER;

EID: 84889687983     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2013.11.003     Document Type: Article

References (27)

1. Maliepaard M., Scheffer G.L., Faneyte I.F., van Gastelen M.A., Pijnenborg A.C.L.M., Schinkel A.H., et al. Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues. Cancer Research 2001, 61:3458-3464.
2. Allikmets R., Schriml L.M., Hutchinson A., Romano-Spica V., Dean M. A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance. Cancer Research 1998, 58:5337-5339.
3. Doyle L.A., Yang W., Abruzzo L.V., Krogmann T., Gao Y., Rishi A.K., et al. A multidrug resistance transporter from human mcf-7 breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America 1998, 95:15665-15670.
4. Ceckova M., Libra A., Pavek P., Nachtigal P., Brabec M., Fuchs R., et al. Expression and functional activity of breast cancer resistance protein (BCRP, ABCG2) transporter in the human choriocarcinoma cell line BeWo. Clinical and Experimental Pharmacology & Physiology 2006, 33:58-65.
5. Evseenko D.A., Murthi P., Paxton J.W., Reid G., Emerald B.S., Mohankumar K.M., et al. The ABC transporter BCRP/ABCG2 is a placental survival factor, and its expression is reduced in idiopathic human fetal growth restriction. FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology 2007, 21:3592-3605.
6. Jonker J.W., Buitelaar M., Wagenaar E., Van Der Valk M.A., Scheffer G.L., Scheper R.J., et al. The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria. Proceedings of the National Academy of Sciences of the United States of America 2002, 99:15649-15654.
7. Enokizono J., Kusuhara H., Sugiyama Y. Effect of breast cancer resistance protein (BCRP/ABCG2) on the disposition of phytoestrogens. Molecular Pharmacology 2007, 72:967-975.
8. Zhang Y., Wang H., Unadkat J.D., Mao Q. Breast cancer resistance protein 1 limits fetal distribution of nitrofurantoin in the pregnant mouse. Drug Metabolism and Disposition: The Biological Fate of Chemicals 2007, 35:2154-2158.
9. Zhou L., Naraharisetti S.B., Wang H., Unadkat J.D., Hebert M.F., Mao Q. The breast cancer resistance protein (BCRP1/ABCG2) limits fetal distribution of glyburide in the pregnant mouse: an Obstetric-Fetal Pharmacology Research Unit Network and University of Washington Specialized Center of Research Study. Molecular Pharmacology 2008, 73:949-959.
10. Pollex E., Lubetsky A., Koren G. The role of placental breast cancer resistance protein in the efflux of glyburide across the human placenta. Placenta 2008, 29:743-747.
11. Kliman H.J. Uteroplacental blood flow. The story of decidualization, menstruation, and trophoblast invasion. American Journal of Pathology 2000, 157:1759-1768.
12. Fox H. Pathology of the placenta 1997, W.B. Saunders Company, Ltd., London.
13. Benirschke K.K.P. Pathology of the placenta 2000, Springer, New York.
14. Wyatt S.M., Kraus F.T., Roh C.R., Elchalal U., Nelson D.M., Sadovsky Y. The correlation between sampling site and gene expression in the term human placenta. Placenta 2005, 26:372-379.
15. Nelson D.M., Burton G.J. A technical note to improve the reporting of studies of the human placenta. Placenta 2011, 32:195-196.
16. Adibi J.J., Hauser R., Williams P.L., Whyatt R.M., Thaker H.M., Nelson H., et al. Placental biomarkers of phthalate effects on mRNA transcription: application in epidemiologic research. Environmental Health: A Global Access Science Source 2009, 8:20.
17. Avila L., Yuen R.K., Diego-Alvarez D., Penaherrera M.S., Jiang R., Robinson W.P. Evaluating DNA methylation and gene expression variability in the human term placenta. Placenta 2010, 31:1070-1077.
18. Brameld J.M., Hold R., Pipkin F.B. Regional variation in angiotensin converting enzyme activity in the human placenta. Placenta 2011, 32:906-908.
19. Krishnamurthy P., Ross D.D., Nakanishi T., Bailey-Dell K., Zhou S., Mercer K.E., et al. The stem cell marker BCRP/ABCG2 enhances hypoxic cell survival through interactions with heme. Journal of Biological Chemistry 2004, 279:24218-24225.
20. Klaassen C.D., Aleksunes L.M. Xenobiotic, bile acid, and cholesterol transporters: function and regulation. Pharmacological Reviews 2010, 62:1-96.
21. Yeboah D., Sun M., Kingdom J., Baczyk D., Lye S.J., Matthews S.G., et al. Expression of breast cancer resistance protein (BCRP/ABCG2) in human placenta throughout gestation and at term before and after labor. Canadian Journal of Physiology and Pharmacology 2006, 84:1251-1258.
22. Mason C.W., Buhimschi I.A., Buhimschi C.S., Dong Y., Weiner C.P., Swaan P.W. ATP-binding cassette transporter expression in human placenta as a function of pregnancy condition. Drug Metabolism and Disposition: The Biological Fate of Chemicals 2011, 39:1000-1007.
23. Tzschoppe A.A., Struwe E., Dorr H.G., Goecke T.W., Beckmann M.W., Schild R.L., et al. Differences in gene expression dependent on sampling site in placental tissue of fetuses with intrauterine growth restriction. Placenta 2010, 31:178-185.
24. Patel P., Boyd C.A., Johnston D.G., Williamson C. Analysis of GAPDH as a standard for gene expression quantification in human placenta. Placenta 2002, 23:697-698.
25. Murthi P., Fitzpatrick E., Borg A.J., Donath S., Brennecke S.P., Kalionis B. GAPDH, 18S rRNA and YWHAZ are suitable endogenous reference genes for relative gene expression studies in placental tissues from human idiopathic fetal growth restriction. Placenta 2008, 29:798-801.
26. Studer D., Lischer S., Jochum W., Ehrbar M., Zenobi-Wong M., Maniura-Weber K. Ribosomal protein l13a as a reference gene for human bone marrow-derived mesenchymal stromal cells during expansion, adipo-, chondro-, and osteogenesis. Tissue Engineering Part C: Methods 2012, 18:761-771.
27. Pidoux G., Gerbaud P., Laurendeau I., Guibourdenche J., Bertin G., Vidaud M., et al. Large variability of trophoblast gene expression within and between human normal term placentae. Placenta 2004, 25:469-473.