-
1
-
-
84863522871
-
Addition of gemtuzumab ozogamicin to induction chemotherapy improves survival in older patients with acute myeloid leukemia
-
A.K. Burnett, N.H. Russell, and R.K. Hills Addition of gemtuzumab ozogamicin to induction chemotherapy improves survival in older patients with acute myeloid leukemia J Clin Oncol 30 2012 3924 3931
-
(2012)
J Clin Oncol
, vol.30
, pp. 3924-3931
-
-
Burnett, A.K.1
Russell, N.H.2
Hills, R.K.3
-
2
-
-
84859911350
-
Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): A randomised, open-label, phase 3 study
-
S. Castaigne, C. Pautas, and C. Terre Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): A randomised, open-label, phase 3 study Lancet 379 2012 1508 1516
-
(2012)
Lancet
, vol.379
, pp. 1508-1516
-
-
Castaigne, S.1
Pautas, C.2
Terre, C.3
-
3
-
-
77957724998
-
Shortcomings in the clinical evaluation of new drugs: Acute myeloid leukemia as paradigm
-
R.B. Walter, F.R. Appelbaum, and M.S. Tallman Shortcomings in the clinical evaluation of new drugs: Acute myeloid leukemia as paradigm Blood 116 2010 2420 2428
-
(2010)
Blood
, vol.116
, pp. 2420-2428
-
-
Walter, R.B.1
Appelbaum, F.R.2
Tallman, M.S.3
-
4
-
-
0024536437
-
Optimal two-stage designs for phase II clinical trials
-
R. Simon Optimal two-stage designs for phase II clinical trials Control Clin Trials 10 1989 1 10
-
(1989)
Control Clin Trials
, vol.10
, pp. 1-10
-
-
Simon, R.1
-
5
-
-
77649194028
-
Single-agent laromustine, a novel alkylating agent, has significant activity in older patients with previously untreated poor-risk acute myeloid leukemia
-
G.J. Schiller, S.M. O'Brien, and A. Pigneux Single-agent laromustine, a novel alkylating agent, has significant activity in older patients with previously untreated poor-risk acute myeloid leukemia J Clin Oncol 28 2010 815 821
-
(2010)
J Clin Oncol
, vol.28
, pp. 815-821
-
-
Schiller, G.J.1
O'brien, S.M.2
Pigneux, A.3
-
6
-
-
77449159668
-
Phase II study of clofarabine monotherapy in previously untreated older adults with acute myeloid leukemia and unfavorable prognostic factors
-
H.M. Kantarjian, H.P. Erba, and D. Claxton Phase II study of clofarabine monotherapy in previously untreated older adults with acute myeloid leukemia and unfavorable prognostic factors J Clin Oncol 28 2010 549 555
-
(2010)
J Clin Oncol
, vol.28
, pp. 549-555
-
-
Kantarjian, H.M.1
Erba, H.P.2
Claxton, D.3
-
7
-
-
69849092737
-
A randomized phase 3 study of tipifarnib compared with best supportive care, including hydroxyurea, in the treatment of newly diagnosed acute myeloid leukemia in patients 70 years or older
-
J.L. Harousseau, G. Martinelli, and W.W. Jedrzejczak A randomized phase 3 study of tipifarnib compared with best supportive care, including hydroxyurea, in the treatment of newly diagnosed acute myeloid leukemia in patients 70 years or older Blood 114 2009 1166 1173
-
(2009)
Blood
, vol.114
, pp. 1166-1173
-
-
Harousseau, J.L.1
Martinelli, G.2
Jedrzejczak, W.W.3
-
8
-
-
84872072793
-
Randomized, phase IIb study of low-dose cytarabine and lintuzumab versus low-dose cytarabine and placebo in older adults with untreated acute myeloid leukemia
-
M.A. Sekeres, J.E. Lancet, and B.L. Wood Randomized, phase IIb study of low-dose cytarabine and lintuzumab versus low-dose cytarabine and placebo in older adults with untreated acute myeloid leukemia Haematologica 98 2013 119 128
-
(2013)
Haematologica
, vol.98
, pp. 119-128
-
-
Sekeres, M.A.1
Lancet, J.E.2
Wood, B.L.3
-
9
-
-
33847001315
-
A phase 2 study of the farnesyltransferase inhibitor tipifarnib in poor-risk and elderly patients with previously untreated acute myelogenous leukemia
-
J.E. Lancet, I. Gojo, and J. Gotlib A phase 2 study of the farnesyltransferase inhibitor tipifarnib in poor-risk and elderly patients with previously untreated acute myelogenous leukemia Blood 109 2007 1387 1394
-
(2007)
Blood
, vol.109
, pp. 1387-1394
-
-
Lancet, J.E.1
Gojo, I.2
Gotlib, J.3
-
10
-
-
84863393263
-
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia
-
J.P. Patel, M. Gonen, and M.E. Figueroa Prognostic relevance of integrated genetic profiling in acute myeloid leukemia N Engl J Med 366 2012 1079 1089
-
(2012)
N Engl J Med
, vol.366
, pp. 1079-1089
-
-
Patel, J.P.1
Gonen, M.2
Figueroa, M.E.3
-
11
-
-
41949125894
-
A 2-gene classifier for predicting response to the farnesyltransferase inhibitor tipifarnib in acute myeloid leukemia
-
M. Raponi, J.E. Lancet, and H. Fan A 2-gene classifier for predicting response to the farnesyltransferase inhibitor tipifarnib in acute myeloid leukemia Blood 111 2008 2589 2596
-
(2008)
Blood
, vol.111
, pp. 2589-2596
-
-
Raponi, M.1
Lancet, J.E.2
Fan, H.3
-
12
-
-
84864050584
-
Clofarabine plus cytarabine compared with cytarabine alone in older patients with relapsed or refractory acute myelogenous leukemia: Results from the CLASSIC I Trial
-
S. Faderl, M. Wetzler, and D. Rizzieri Clofarabine plus cytarabine compared with cytarabine alone in older patients with relapsed or refractory acute myelogenous leukemia: Results from the CLASSIC I Trial J Clin Oncol 30 2012 2492 2499
-
(2012)
J Clin Oncol
, vol.30
, pp. 2492-2499
-
-
Faderl, S.1
Wetzler, M.2
Rizzieri, D.3
-
13
-
-
84872176951
-
Clonal evolution of acute leukemia genomes
-
M. Jan, and R. Majeti Clonal evolution of acute leukemia genomes Oncogene 32 2013 135 140
-
(2013)
Oncogene
, vol.32
, pp. 135-140
-
-
Jan, M.1
Majeti, R.2
-
14
-
-
55049108527
-
In vivo maintenance of synergistic cytarabine:daunorubicin ratios greatly enhances therapeutic efficacy
-
P. Tardi, S. Johnstone, and N. Harasym In vivo maintenance of synergistic cytarabine:daunorubicin ratios greatly enhances therapeutic efficacy Leuk Res 33 2009 129 139
-
(2009)
Leuk Res
, vol.33
, pp. 129-139
-
-
Tardi, P.1
Johnstone, S.2
Harasym, N.3
-
15
-
-
79952757852
-
First-in-man study of CPX-351: A liposomal carrier containing cytarabine and daunorubicin in a fixed 5:1 molar ratio for the treatment of relapsed and refractory acute myeloid leukemia
-
E.J. Feldman, J.E. Lancet, and J.E. Kolitz First-in-man study of CPX-351: A liposomal carrier containing cytarabine and daunorubicin in a fixed 5:1 molar ratio for the treatment of relapsed and refractory acute myeloid leukemia J Clin Oncol 29 2011 979 985
-
(2011)
J Clin Oncol
, vol.29
, pp. 979-985
-
-
Feldman, E.J.1
Lancet, J.E.2
Kolitz, J.E.3
-
16
-
-
81255127741
-
Phase 2b randomized study of CPX-351 vs cytarabine (CYT)+daunorubicin (DNR) (7+3 regimen) in newly diagnosed AML patients aged 60-75
-
abstr 655
-
J.E. Lancet, J.E. Cortes, and D.E. Hogge Phase 2b randomized study of CPX-351 vs cytarabine (CYT)+daunorubicin (DNR) (7+3 regimen) in newly diagnosed AML patients aged 60-75 Blood (ASH Annual Meeting Abstracts) 116 2010 abstr 655
-
(2010)
Blood (ASH Annual Meeting Abstracts)
, vol.116
-
-
Lancet, J.E.1
Cortes, J.E.2
Hogge, D.E.3
-
17
-
-
84889646919
-
Randomized phase 2 trial of timed-sequential therapy (TST) with flavopiridol (Alvocidib), Ara-C and mitoxantrone (FLAM) versus "7+3" for adults ages 70 years and under with newly diagnosed acute myeloid leukemia (AML)
-
abstr 47
-
J.F. Zeidner, J.M. Gerber, and A. Blackford Randomized phase 2 trial of timed-sequential therapy (TST) with flavopiridol (Alvocidib), Ara-C and mitoxantrone (FLAM) versus "7+3" for adults ages 70 years and under with newly diagnosed acute myeloid leukemia (AML) Blood (ASH Annual Meeting Abstracts) 120 2012 abstr 47
-
(2012)
Blood (ASH Annual Meeting Abstracts)
, vol.120
-
-
Zeidner, J.F.1
Gerber, J.M.2
Blackford, A.3
-
18
-
-
79953124734
-
Results from a randomized trial of salvage chemotherapy followed by lestaurtinib for patients with FLT3 mutant AML in first relapse
-
M. Levis, F. Ravandi, and E.S. Wang Results from a randomized trial of salvage chemotherapy followed by lestaurtinib for patients with FLT3 mutant AML in first relapse Blood 117 2011 3294 3301
-
(2011)
Blood
, vol.117
, pp. 3294-3301
-
-
Levis, M.1
Ravandi, F.2
Wang, E.S.3
-
19
-
-
84875592100
-
Final results of a phase 2 open-label, monotherapy efficacy and safety study of quizartinib (AC220) in patients >60 years of age with FLT3 ITD positive or negative relapsed/refractory acute myeloid leukemia
-
abstr 48
-
J.E. Cortes, A.E. Perl, and H. Dombret Final results of a phase 2 open-label, monotherapy efficacy and safety study of quizartinib (AC220) in patients >60 years of age with FLT3 ITD positive or negative relapsed/refractory acute myeloid leukemia Blood (ASH Annual Meeting Abstracts) 120 2012 abstr 48
-
(2012)
Blood (ASH Annual Meeting Abstracts)
, vol.120
-
-
Cortes, J.E.1
Perl, A.E.2
Dombret, H.3
-
20
-
-
84875635430
-
Final results of a phase 2 open-label, monotherapy efficacy and safety study of quizartinib (AC220) in patients with FLT3-ITD positive or negative relapsed/refractory acute myeloid leukemia after second-line chemotherapy or hematopoietic stem cell transplantation
-
abstr 673
-
M.J. Levis, A.E. Perl, and H. Dombret Final results of a phase 2 open-label, monotherapy efficacy and safety study of quizartinib (AC220) in patients with FLT3-ITD positive or negative relapsed/refractory acute myeloid leukemia after second-line chemotherapy or hematopoietic stem cell transplantation Blood (ASH Annual Meeting Abstracts) 120 2012 abstr 673
-
(2012)
Blood (ASH Annual Meeting Abstracts)
, vol.120
-
-
Levis, M.J.1
Perl, A.E.2
Dombret, H.3
|