Precordial R wave height does not correlate with echocardiographic findings in boys with duchenne muscular dystrophy

Congenital Heart Disease

Volumn 8, Issue 6, 2013, Pages 561-567

  Thrush, Philip T ^a,b   Edward, Neeraj ^c   Flanigan, Kevin M ^a,b   Mendell, Jerry R ^a,b   Allen, Hugh D ^a,b,d  

^a NATIONWIDE CHILDREN S HOSPITAL   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^d TEXAS CHILDREN S HOSPITAL   (United States)

Author keywords

Cardiomyopathy; Duchenne Muscular Dystrophy; Dystrophinopathy; Electrocardiography

Indexed keywords

ADOLESCENT; ADULT; AGE DISTRIBUTION; ARTICLE; CARDIOMYOPATHY; CARDIOVASCULAR PARAMETERS; CHILD; CHILDHOOD DISEASE; CONTROLLED STUDY; CORRELATION COEFFICIENT; DUCHENNE MUSCULAR DYSTROPHY; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAM; HEART EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICULAR ENDDIASTOLIC DIMENSION; HEART RIGHT VENTRICLE HYPERTROPHY; HUMAN; INFANT; LINEAR REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; R WAVE; SCHOOL CHILD;

CARDIOMYOPATHY; DUCHENNE MUSCULAR DYSTROPHY; DYSTROPHINOPATHY; ELECTROCARDIOGRAPHY;

ADOLESCENT; ADULT; AGE FACTORS; CARDIOMYOPATHIES; CHILD; CHILD, PRESCHOOL; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; HUMANS; INFANT; LINEAR MODELS; MALE; MUSCULAR DYSTROPHY, DUCHENNE; MYOCARDIAL CONTRACTION; PREDICTIVE VALUE OF TESTS; SEX FACTORS; STROKE VOLUME; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR FUNCTION, LEFT; VENTRICULAR REMODELING; YOUNG ADULT;

EID: 84889606136     PISSN: 1747079X     EISSN: 17470803     Source Type: Journal    
DOI: 10.1111/chd.12049     Document Type: Article

References (21)

1. Mendell JR, Shilling C, Leslie ND, etal. Evidence-based path to newborn screening for Duchenne muscular dystrophy. Ann Neurol. 2012;71:304-313.
2. Ervasti JM, Campbell KP. Membrane organization of the dystrophin-glycoprotein complex. Cell. 1991;66:1121-1131.
3. Constantin B, Sebille S, Cognard C. New insights in the regulation of calcium transfers by muscle dystrophin-based cytoskeleton: implications in DMD. J Muscle Res Cell Motil. 2006;27:375-386.
4. Feng J, Schaus BJ, Fallavollita JA, Lee TC, Canty JM, Jr. Preload induces troponin I degradation independently of myocardial ischemia. Circulation. 2001;103:2035-2037.
5. Williams IA, Allen DG. Intracellular calcium handling in ventricular myocytes from mdx mice. Am J Physiol Heart Circ Physiol. 2007;292:H846-H855.
6. Allen H, Mendell JR, Hoffman TM. Chapter 60. The Heart in Muscular Dystrophies. Philadelphia, PA: Lippincott Williams & Wilkins; 2008.
7. Manning GW, Cropp GJ. The electrocardiogram in progressive muscular dystrophy. Br Heart J. 1958;20:416-420.
8. Perloff JK, Roberts WC, de Leon AC, Jr, O'Doherty D. The distinctive electrocardiogram of Duchenne's progressive muscular dystrophy. An electrocardiographic-pathologic correlative study. Am J Med. 1967;42:179-188.
9. Bhattacharyya KB, Basu N, Ray TN, Maity B. Profile of electrocardiographic changes in Duchenne muscular dystrophy. J Indian Med Assoc. 1997;95:40-42.
10. Thrush PT, Allen HD, Viollet L, Mendell JR. Re-examination of the electrocardiogram in boys with Duchenne muscular dystrophy and correlation with its dilated cardiomyopathy. Am J Cardiol. 2009;103:262-265.
11. Shah AM, Jefferies JL, Rossano JW, Decker JA, Cannon BC, Kim JJ. Electrocardiographic abnormalities and arrhythmias are strongly associated with the development of cardiomyopathy in muscular dystrophy. Heart Rhythm. 2010;7:1484-1488.
12. Takami Y, Takeshima Y, Awano H, Okizuka Y, Yagi M, Matsuo M. High incidence of electrocardiogram abnormalities in young patients with Duchenne muscular dystrophy. Pediatr Neurol. 2008;39:399-403.
13. Perloff JK. Cardiac rhythm and conduction in Duchenne's muscular dystrophy: a prospective study of 20 patients. J Am Coll Cardiol. 1984;3:1263-1268.
14. Sanyal SK, Johnson WW, Thapar MK, Pitner SE. An ultrastructural basis for electrocardiographic alterations associated with Duchenne's progressive muscular dystrophy. Circulation. 1978;57:1122-1129.
15. Duboc D, Meune C, Lerebours G, Devaux JY, Vaksmann G, Becane HM. Effect of perindopril on the onset and progression of left ventricular dysfunction in Duchenne muscular dystrophy. J Am Coll Cardiol. 2005;45:855-857.
16. Duboc D, Meune C, Pierre B, etal. Perindopril preventive treatment on mortality in Duchenne muscular dystrophy: 10 years' follow-up. Am Heart J. 2007;154:596-602.
17. Ogata H, Ishikawa Y, Minami R. Beneficial effects of beta-blockers and angiotensin-converting enzyme inhibitors in Duchenne muscular dystrophy. J Cardiol. 2009;53:72-78.
18. Ramaciotti C, Heistein LC, Coursey M, etal. Left ventricular function and response to enalapril in patients with Duchenne muscular dystrophy during the second decade of life. Am J Cardiol. 2006;98:825-827.
19. Viollet L, Thrush PT, Flanigan KM, Mendell JR, Allen HD. Effects of angiotensin-converting enzyme inhibitors and/or beta blockers on the cardiomyopathy in Duchenne muscular dystrophy. Am J Cardiol. 2012;110:98-102.
20. James J, Kinnett K, Wang Y, Ittenbach RF, Benson DW, Cripe L. Electrocardiographic abnormalities in very young Duchenne muscular dystrophy patients precede the onset of cardiac dysfunction. Neuromuscul Disord. 2011;21:462-467.
21. Mazur W, Hor KN, Germann JT, etal. Patterns of left ventricular remodeling in patients with Duchenne muscular dystrophy: a cardiac mri study of ventricular geometry, global function, and strain. Int J Cardiovasc Imaging. 2012;28:99-107.