Infliximab-related hepatitis: A case study and literature review

Digestive Diseases and Sciences

Volumn 58, Issue 11, 2013, Pages 3362-3367

  Colina, Francisco ^a   Molero, Aída ^a   Casís, Begoña ^a   Martínez Montiel, Pilar ^a  

^a HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

Author keywords

Adverse reactions; Autoimmune hepatitis; Immunomediated hepatitis; Infliximab related hepatitis; TNF alpha; TNF blockers

Indexed keywords

ALANINE AMINOTRANSFERASE; BILIRUBIN; CEROID; GAMMA GLUTAMYLTRANSFERASE; IMMUNOGLOBULIN M; INFLIXIMAB; LACTATE DEHYDROGENASE; PREDNISONE; STEROID;

ABDOMINAL PAIN; ADULT; ANAMNESIS; ARTICLE; CASE REPORT; DRUG DOSE REDUCTION; DRUG MEGADOSE; DRUG WITHDRAWAL; EOSINOPHIL; FEMALE; FOLLOW UP; HEPATITIS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INFLAMMATORY INFILTRATE; KUPFFER CELL; LIVER BIOPSY; LIVER DYSFUNCTION; LYMPHOCYTIC INFILTRATION; NEUTROPHIL CHEMOTAXIS; OUTCOME ASSESSMENT; PLASMA CELL; PORTAL VEIN; PRIORITY JOURNAL; RECTUM HEMORRHAGE; REMISSION; TOXIC HEPATITIS; ULCERATIVE COLITIS; WEIGHT REDUCTION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIBODIES, MONOCLONAL; COLITIS, ULCERATIVE; DRUG-INDUCED LIVER INJURY; FEMALE; HUMANS; MIDDLE AGED;

EID: 84889563638     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-013-2698-6     Document Type: Article

References (28)

1. Subramaniam K, Chitturi S, Brown M. Infliximab-induced autoimmune hepatitis in Crohn's disease treated with budesonide and mycophenolate. Inflamm Bowel Dis. 2011;17:E149-E150.
2. Doyle A, Forbes G, Kontorinis N. Autoimmune hepatitis during infliximab therapy for Crohn's disease: a case report. J Crohns Colitis. 2011;5:253-255.
3. Goujon C, Dahel K, Bérard F, Guillot I, Gunera-Saad N. Autoimmune hepatitis in two psoriasis patients treated with infliximab. J Am Acad Dermatol. 2010;63:43-44.
4. Carlsen KM, Riis L, Madsen OR. Toxic hepatitis induced by infliximab in a patient with rheumatoid arthritis with no relapse after switching to etanercep. Clin Rheumatol. 2009;28:1001-1003.
5. Polin Y, Thérien G. Drug-induced hepatitis and lupus during infliximab treatment for psoriasis: case report and literature review. J Cutan Med Surg. 2010;14:100-104.
6. Cravo M, Silva R, Serrano M. Autoimmune hepatitis induced by infliximab in a patient with Crohn's disease with no relapse after switching to adalimumab. Biodrugs. 2010;24:25-27.
7. Thiéfin G, Morelet A, Heurgué A, Diebold MD, Eschard JP. Infliximab-induced hepatitis. Absence of cross-toxicity with etanercept. Joint Bone Spine. 2008;75:737-739.
8. Marques M, Magro F, Cardoso H, Carneiro F. Infliximab-induced lupus-like syndrome associated with autoimmune hepatitis. Inflamm Bowel Dis. 2008;14:723-725.
9. Ozorio G, McGarity B, Bak H, Jordan AS, Lau H, Marshall C. Autoimmune hepatitis following infliximab therapy for ankylosing spondylitis. Med J Aust. 2007;187:524-526.
10. Tobon GJ, Cañas C, Jaller JJ, Restrepo JC, Anaya JM. Serious liver disease induced by infliximab. Clin Rheumatol. 2007;26:578-581.
11. Germano V, Picchianti A, Baccano G, et al. Autoimmune hepatitis associated with infliximab in a patient with psoriatic arthritis. Ann Rheum Dis. 2005;64:1519-1520.
12. Ojiro K, Naganuma M, Ebinuma H, et al. Reactivation of hepatitis B in a patient with Crohn's disease treated using infliximab. J Gastroenterol. 2008;43:397-401.
13. Madonia S, Orlando A, Scimeca D, Olivo M, Rossi F, Cottone M. Occult hepatitis B and infliximab-induced HBV reactivation. Inflamm Bowel Dis. 2007;13:508-509.
14. Millonig G, Kern M, Ludwiczek O, Nachbaur K, Vogel W. Subfulminant hepatitis B after infliximab in Crohn's disease: need for HBV-screening? World J Gastroenterol. 2006;12:974-976.
15. Ueno Y, Tanaka S, Shimamoto M, et al. Infliximab therapy for Crohn's disease in a patient with chronic hepatitis B. Dig Dis Sci. 2005;50:163-165.
16. Michel M, Duvoux C, Hezode C, Cherqui D. Fulminant hepatitis after infliximab in a patient with hepatitis B virus treated for and adult onset Still's disease. J Rheumatol. 2003;30:1624-1625.
17. Kuwabara H, Fukuda A, Tsuda Y, Shibayama Y. Precore mutant hepatitis B virus associated fulminant hepatitis during infliximab therapy for rheumatoid arthritis. Clin Rheumatol. 2010;29:449-450.
18. Wahie S, Alexandroff A, Reynolds NJ. Hepatitis: a rare, but important, complication of infliximab therapy for psoriasis. Clin Exp Dermatol. 2006;31:460-461.
19. Ierardi E, Della Valle N, Nacchiero MC, De Francesco V, Stoppino G, Panella C. Onset of liver damage after a single administration of infliximab in a patient with refractory ulcerative colitis. Clin Drug Invest. 2006;26:673-676.
20. García Aparicio AM, Rey JR, Sanz AH, Alvarez JS. Successful treatment with etanercep in a patient with hepatotoxicity closely related to infliximab. Clin Rheumatol. 2007;26:811-813.
21. Fairhurst A, Sheehan-Dare R. Autoimmune hepatitis associated with infliximab in a patient with palmoplantar pustular psoriasis. Clin Exp Dermatol. 2008;34:402-425.
22. Kluger N, Girard C, Guillot B, Bessis D. Efficiency and safety of etanercep after acute hepatitis induced by infliximab for psoriasis. Acta Derm-Venereol. 2009;89:332-333.
23. Soto Fernández S, Gónzalez Carro P, de Pedro Esteban A, et al. Infliximab-induced hepatitis in a patient with Crohn's disease. Gastroenterol Hepatol. 2006;29:321-322.
24. Mancini S, Amarotti E, Vecchio S, Ponz de Leon M, Roncucci L. Infliximab-related hepatitis: discussion of a case and review of the literature. Intern Emerg Med. 2010;5:193-200.
25. Menghini VV, Arora AS. Infliximab-associated reversible cholestatic liver disease. Mayo Clin Proc. 2001;76:84-86.
26. Scheuer PJ. Classification of chronic viral hepatitis: a need for reassessment. J Hepatol. 1991;13:372-374.
27. Marinos G. TNF receptors in patients with chronic hepatitis B viral infection. Gastroenterology. 1995;108:1453-1463.
28. Weiler-Normann C, Schramm C. Drug induced liver injury and its relationship to autoimmune hepatitis. J Hepatol. 2011;55:747-749.