Non-Parathyroid Hypercalcemia

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism: Seventh Edition

Volumn , Issue , 2009, Pages 307-312

  Horwitz, Mara J ^a   Hodak, Steven P ^a   Stewart, Andrew F ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Cancer; Granulomatous disease; Humoral hypercalcemia of malignancy; Hypercalcemia; Hyperthyroidism; Immobilization; Medications; Milk alkali syndrome; Osteolytic hypercalcimia; Vitamin D toxicity

Indexed keywords

EID: 84889400837     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470623992.ch67     Document Type: Chapter

References (49)

1. Adams JS, Gacad MA 1985 Characterization of 1 hydroxylation of vitamin D3 sterols by cultured alveolar macrophages from patients with sarcoidosis. J Exp Med 161:755-765.
2. Barbour GL, Coburn JW, Slatopolsky E, Norman AW, Horst RL 1981 Hypercalcemia in an anephric patient with sarcoidosis: Evidence for extrarenal generation of 1,25-dihydroxy vitamin D. N Engl J Med 305:440-443.
3. Beall DP. Scofield RH 1995 Milk-alkali syndrome associated with calcium carbonate consumption. Medicine 74:89-96.
4. Bergstrom WH 1978 Hypercalciuria and hypercalcemia complicating immobilization. Am J Dis Child 132:553-554.
5. Burtis WJ, Brady TG, Orloff JJ, Ersbak JB, Warrell RP, Olson BR, Wu TL, Mitnick MA, Broadus AE, Stewart AF 1990 Immunochemical characterization of circulating parathyroid hormone-related protein in patients with humoral hypercalcemia of malignancy. N Engl J Med 322:1106-1112.
6. Chandra SV, Shukla GS, Srivastava RS 1981 An exploratory study of manganese exposure to welders. Clin Toxicol 18:407-416.
7. Chappard D, Minaire P, Privat C, Berard E, Mendoza-Sarmiento J, Tournebise H, Basle MH, Audran W, Rebel A, Picot C 1995 Effects of tiludronate on bone loss in paraplegic patients. J Bone Miner Res 10:112-118.
8. Elfatih A, Anderson NR, Fahie-Wilson MN, Gama R 2007 Pseudo-pseudohypercalcaemia, apparent primary hyperparathyroidism and Waldenstrom's macroglobulinaemia. J Clin Pathol 60:436-437.
9. Evans KN, Taylor H, Zehnder D, Kilby MD, Bulmer JN. Shah F, Adams JS, Hewison M 2004 Increased expression of 25-hydroxyvitamin D-lalpha-hydroxylase in dysgerminomas: A novel form of humoral hypercalcemia of malignancy. Am J Pathol 165:807-813.
10. Gayet S, Ville E, Durand JM, Mars ME, Morange S, Kaplanski G, Gallais H, Soubeyrand J 1997 Foscarnet-induced hypercalcemia in AIDS. AIDS 11:1068-1070.
11. Gerhardt A, Greenberg A, Reilly JJ, Van Thiel DH 1987 Hypercal-cema complication of advanced chronic liver disease. Arch Intern Med 147:274-277.
12. Ghaferi AA, Chojnacki KA, Long WD, Cameron JL, Yeo CJ 2008 Pancreatic Vipomas: Subject Review and One Institutional Experience. J Gastrointest Surg 12:382-393.
13. Gkonos PJ, London R, Hendler ED 1984 Hypercalcemia and elevated 1,25-dihydroxyvitamin D levels in a patient with end stage renal disease and active tuberculosis. N Engl J Med 311:1683-1685.
14. Haden ST, Stoll AL, McCormick S, Scott J, Fuleihan GE 1979 Alterations in parathyroid dynamics in lithium-treated subjects. J Clin Endocrinol Metab 82:2844-2848.
15. Holick MF, Shao Q, Liu WW, Chen TC 1992 The vitamin D content of fortified milk and infant formula. N Engl J Med 326:1178-1181.
16. Horwitz MJ, Tedesco MB, Sereika SM, Syed MA, Garcia-Ocana A, Bisello A, Hollis BW, Rosen CJ, Wysolmerski JJ, Dann P, Gund-berg CM, Stewart AF 2005 Continuous infusion of parathyroid hormone versus parathyroid hormone-related protein in humans: Discordant effects on l,25(OH)2 vitamin D and prolonged suppression of bone formation. J Bone Miner Res 20:1792-1803.
17. Jacobus CH, Holick MF, Shao Q, Chen TC, Holm IA, Kolodny JM, Fuleihan GE, Seely EW 1992 Hypervitaminosis D. associated with drinking milk. N Engl J Med 326:1173-1177.
18. Klein GL, Horst RL, Norman AW, Ament ME, Slatopolsky E, Co-burn JW 1981 Reduced serum levels of la, 25-dihydroxyvitamin D during long-term total parenteral nutrition. Ann Intern Med 94:638-643.
19. Knox JB, Demling RH, Wilmore DW, Sarraf P, Santos AA 1995 Hypercalcemia associated with the use of human growth hormone in an adult surgical intensive care unit. Arch Surg 130:442-145.
20. Llach F, Felsenfeld AJ, Haussler MR 1981 The pathophysiology of altered calcium metabolism in rhabdomyolysis-induced acute renal failure. N Engl J Med 305:117-123.
21. McPherson ML, Prince SR, Atamer E, Maxwell DB. Ross-Clunis H, Estep H 1986 Theophylline-induced hypercalcemia. Ann Intern Med 105:52-54.
22. Merlini G, Fitzpatrick LA, Siris ES, Bilezikian JP, Birken A, Beychok A, Osserman EF 1984 A human myeloma immunoglobulin G binding four moles of calcium associated with asymptomatic hypercalcemia. J Clin Immunol 4:185-196.
23. Miller PD, Bilezikian JP, Diaz-Curiel M, Chen P, Marin F, Krege JH, Wong M, Marcus R 2007 Occurrence of hypercalciuria in patients with osteoporosis treated with teriparatide. J Clin Endocrinol Metab 92:3535-3541.
24. Muls E, Bouillon R, Boelaert J, Lamberigts G, Van Imschool S, Da-neels P, DeMoor P 1982 Etiology of hypercalcemia in a patient with Addison's disease. Calcif Tissue Int 34:523-526.
25. Mune T, Katakami H, Kato Y, Yasuda K, Matsukura S, Miura K 1993 Production and secretion of parathyroid hormone-related protein in pheochromocytoma: Participation of an a-adrenergic mechanism. J Clin Endocrinol Metab 76:757-762.
26. Nussbaum SR, Gaz RD, Arnold A 1990 Hypercalcemia and ectopic secretion of PTH by an ovarian carcinoma with rearrangement of the gene for PTH. N Engl J Med 323:1324-1328.
27. Orwoll ES 1982 The milk-alkali syndrome: Current concepts. Ann Intern Med 97:242-248.
28. Ott SM, Maloney NA, Klein GL, Alfrey AC, Ament ME, Lobourn JW 1983 Aluminum is associated with low bone formation in patients receiving chronic parenteral nutrition. Ann Intern Med 96:910-914.
29. Parker MS, Dokoh S. Woolfenden JM, Buchsbaum HW 1984 Hypercalcemia in coccidioidomycosis. Am J Med 76:341-343.
30. Porter RH, Cox BG, Heaney D, Hostetter TH, Stinebaugh BJ, Suki WN 1978 Treatment of hypoparathyroid patients with chlorthalidone. N Engl J Med 298:577.
31. Roodman GD 2004 Mechanisms of bone metastasis. N Engl J Med 350:1655-1664.
32. Rosen HN, Moses AC, Gundberg C, Kung VT. Seyedin SM, Chen T, Holick M, Greenspan SL 1993 Therapy with parenteral Pamidronate prevents thyroid hormone-induced bone turnover in humans. J Clin Endocrinol Metab 77:664-669.
33. Rosenthal N, Insogna KL, Godsall JW, Smaldone L, Waldron JA, Stewart AF 1985 Elevations in circulating 1,25 dihydroxyvitamin D in three patients with lymphoma-associated hypercalcemia. J Clin Endocrinol Metab 60:29-33.
34. Ross DS, Nussbaum SR 1989 Reciprocal changes in parathyroid hormone and thyroid function after radioiodine treatment of hyperthyroidism. J Clin Endocrinol Metab 68:1216-1219.
35. Sakoulas G, Tritos NA, Lally M, Wanke C, Hartzband P 1997 Hypercalcemia in an AIDS patient treated with growth hormone. AIDS 11:1353-1356.
36. Sarkar S, Hussain N, Herson V 2003 Fibrin Glue for Persistent Pneumothorax in Neonates. J Perinatol 23:82-84.
37. Saunders MP. Salisbury AJ, O'Byrne KJ, Long L, Whitehouse RM, Talbot DC, Mawer EB, Harris AL 1997 A novel cyclic adenosine monophosphate analog induces hypercalcemia via production of 1,25-dihydroxyvitamin D in patients with solid tumors. J Clin Endocrinol Metab 83:4044-4048.
38. Stewart AF 2005 Hypercalcemia Associated with Cancer. N Engl J Med 352:373-379.
39. Stewart AF, Adler M, Byers CM, Segre GV, Broadus AE 1982 Calcium homeostasis in immobilization: An example of resorptive hypercalciuria. N Engl J Med 306:1136-1140.
40. Stewart AF, Broadus AE 2006 Malignancy-associated hypercalcemia. In: DeGroot L. Jameson LJ (eds.) Endocrinology, 5th ed. Saunders, Philadelphia, PA, USA, pp. 1555-1565.
41. Stewart AF, Hoecker J, Segre GV, Mallette LE, Amatruda T, Vignery A 1985 Hypercalcemia in pheochromocytoma: Evidence for a novel mechanism. Ann Intern Med 102:776-779.
42. Stewart AF, Horst R, Deftos LJ, Cadman EC, Lang R, Broadus AE 1980 Biochemical evaluation of patients with cancer-associated hypercalcemia: Evidence for humoral and non-humoral groups. N Engl J Med 303:1377-1383.
43. Stewart AF, Vignery A, Silvergate A, Ravin ND, LiVolsi V, Broadus AE, Baron R 1982 Quantitative bone histomorphometry in humoral hypercalcemia of malignancy: Uncoupling of bone cell activity. J Clin Endocrinol Metab 55:219-227.
44. Valente JD, Elias AN, Weinstein GD 1983 Hypercalcemia associated with oral isotretinoin in the treatment of severe acne. JAMA 250:1899.
45. Valentin-Opran A. Eilon G, Saez S, Mundy GR 1985 Estrogens stimulate release of bone-resorbing activity in cultured human breast cancer cells. J Clin Invest 72:726-731.
46. Vasikaran SD, Tallis GA, Braund WJ 1994 Secondary hypoadrenalism presenting with hypercalcaemia. Clin Endocrinol (Oxf) 41:261-265.
47. Verner JV, Morrison AB 1974 Endocrine pancreatic islet disease with diarrhea. Arch Intern Med 133:492-500.
48. Villablanca J, Khan AA, Avramis VI, Seeger RC, Matthay KC, Ramsay NK, Reynolds CP 1995 Phase I trail of 13-d.s-retinoic acid in children with neuroblastoma following bone marrow transplantation. J Clin Oncol 13:894-901.
49. Wermers RA, Kearns AE, Jenkins GD, Melton LJ III 2007 Incidence and clinical spectrum of thiazide-associated hypercalcemia. Am J Med 120:911.e9-911.el5