Pathophysiology of Type 2 Diabetes

Diabetes in Clinical Practice: Questions and Answers from Case Studies

Volumn , Issue , 2006, Pages 43-58

  Makrilakis, Konstantinos ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

Euglycaemic hyperinsulinaemic clamp technique; Insulin resistance measurement and MODY (Maturity Onset Diabetes of the Young); Latent Autoimmune Diabetes in Adults (LADA); Peripheral insulin resistance cause; Type 2 diabetes pathophysiology

Indexed keywords

EID: 84889338838     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470059142.ch3     Document Type: Chapter

References (6)

1. Creutzfeldt, W. (2001) The entero-insular axis in type 2 diabetes-incretins as therapeutic agents. Exp Clin Endocrinol Diabetes, 109(Suppl 2), S288-S303.
2. Fajans, S.S., Bell, G.I., Polonsky, K.S. (2001) Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young. N Engl J Med, 345, 971-80.
3. Yki-Jarvinen, H. (2003) Insulin resistance in type 2 diabetes, in Textbook of Diabetes, 3rd edn (eds J. Pickup and G. Williams) Blackwell Science Ltd, Oxford, 22, pp. 1-19.
4. Gerich, J.E. and Smith. T.S. (2003) B-cell defects and pancreatic abnormalities in type 2 diabetes, in Textbook of Diabetes, 3rd edn, (eds J. Pickup and G. Williams) Blackwell Science Ltd, Oxford, 23, pp. 1-11.
5. Matthews, D.R., Cull, C.A., Stratton, I.M., Holman, R.R., Turner, R.C. (1998) UK Prospective Diabetes Study (UKPDS) Group. UKPDS 26: sulphonylurea failure in non-insulin-dependent diabetic patients over six years. Diabet Med, 15, 297-303.
6. Vionnet, N., Stoffel, M., Takeda, H. et al. (1992) Nonsense mutation in the glucokinase gene causes early onset non-insulin-dependent diabetes mellitus. Nature, 356, 721-22.