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Volumn , Issue , 2007, Pages 1-13

Overview: Drug Metabolism in the Modern Pharmaceutical Industry

Author keywords

Metabolizing enzyme polymorphisms; Nuclear magnetic resonance spectroscopy; Pharmaceutical biotransformation safety and efficacy

Indexed keywords


EID: 84889271935     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470191699.ch1     Document Type: Chapter
Times cited : (1)

References (6)
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    • 4143147349 scopus 로고    scopus 로고
    • Discovering drugs through biological transformation: role of pharmacologically active metabolites in drug discovery
    • Fura A, Shu YZ, Zhu M, Hanson RL, Roongta V, Humphreys WG. Discovering drugs through biological transformation: role of pharmacologically active metabolites in drug discovery. J Med Chem 2004;47(18):4339-4351.
    • (2004) J Med Chem , vol.47 , Issue.18 , pp. 4339-4351
    • Fura, A.1    Shu, Y.Z.2    Zhu, M.3    Hanson, R.L.4    Roongta, V.5    Humphreys, W.G.6
  • 3
    • 84889416548 scopus 로고    scopus 로고
    • Are most toxicities caused by reactive metabolites?
    • In: Molecular Toxicology, Josephy PD, Mannervik AB, editors. New York: Oxford University Press
    • Grossman, SJ. Are most toxicities caused by reactive metabolites? In: Molecular Toxicology, Josephy PD, Mannervik AB, editors. New York: Oxford University Press; 2006. p 373-374.
    • (2006) , pp. 373-374
    • Grossman, S.J.1
  • 4
    • 78651059557 scopus 로고
    • Biochemical investigations on hepatic carcinogenesis
    • Miller EC, Miller JA. Biochemical investigations on hepatic carcinogenesis. J Natl Cancer Inst 1955;15(5 Suppl):1571-1590.
    • (1955) J Natl Cancer Inst , vol.15 , Issue.5 SUPPL , pp. 1571-1590
    • Miller, E.C.1    Miller, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.