Risk stratifi cation at diagnosis for children with hypertrophic cardiomyopathy: An analysis of data from the Pediatric Cardiomyopathy Registry

The Lancet

Volumn 382, Issue 9908, 2013, Pages 1889-1897

  Lipshultz, Steven E ^a   Orav, E John ^b   Wilkinson, James D ^a   Towbin, Jeffrey A ^c   Messere, Jane E ^d   Lowe, April M ^e   Sleeper, Lynn A ^e   Cox, Gerald F ^d,f   Hsu, Daphne T ^g   Canter, Charles E ^h   Hunter, Juanita A ^a   Colan, Steven D ^d  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

^e NEW ENGLAND RESEARCH INSTITUTES   (United States)

^f GENZYME CORPORATION   (United States)

^g ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^h WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGE DISTRIBUTION; ARTICLE; BODY WEIGHT; CARDIOVASCULAR MORTALITY; CARDIOVASCULAR RISK; CHILD; CHILDHOOD MORTALITY; COMORBIDITY; CONGESTIVE CARDIOMYOPATHY; CONGESTIVE HEART FAILURE; END DIASTOLIC VENTRICULAR SEPTAL THICKNESS; FEMALE; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE SIZE; HEART TRANSPLANTATION; HEART VENTRICLE SEPTUM; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; INBORN ERROR OF METABOLISM; LEFT VENTRICULAR END DIASTOLIC POSTERIOR WALL THICKNESS; LEFT VENTRICULAR FRACTIONAL SHORTENING; MAJOR CLINICAL STUDY; MALE; MALFORMATION SYNDROME; PHENOTYPE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROGNOSIS; RESTRICTIVE CARDIOMYOPATHY; RISK ASSESSMENT; SCHOOL CHILD; CANADA; KAPLAN MEIER METHOD; METHODOLOGY; MORTALITY; MULTICENTER STUDY; REGISTER; UNITED STATES; UTILIZATION REVIEW; CARDIOMYOPATHY, HYPERTROPHIC; CLINICAL TRIAL; COMPLICATION; EPIDEMIOLOGY; PROCEDURES; UTILIZATION;

CANADA; CARDIOMYOPATHY, HYPERTROPHIC; CHILD; CHILD, PRESCHOOL; FEMALE; HEART TRANSPLANTATION; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; METABOLISM, INBORN ERRORS; PROGNOSIS; REGISTRIES; RISK ASSESSMENT; UNITED STATES;

EID: 84889259037     PISSN: 01406736     EISSN: 1474547X     Source Type: Journal    
DOI: 10.1016/S0140-6736(13)61685-2     Document Type: Article

References (30)

1. Richardson P, McKenna W, Bristow M, et al. Report of the 1995 World Health Organization International Society and Federation of Cardiology Task Force on the defi nition and classifi cation of cardiomyopathies. Circulation 1996; 93: 841-42.
2. Maron BJ, Tajik AJ, Ruttenberg HD, et al. Hypertrophic cardiomyopathy in infants: clinical features and natural history. Circulation 1982; 65: 7-17.
3. Suda K, Kohl T, Kovalchin JP, Silverman NH. Echocardiographic predictors of poor outcome in infants with hypertrophic cardiomyopathy. Am J Cardiol 1997; 80: 595-600.
4. Schaff er MS, Freedom RM, Rowe RD. Hypertrophic cardiomyopathy presenting before 2 years of age in 13 patients. Pediatr Cardiol 1983; 4: 113-19.
5. Bruno E, Maisuls H, Juaneda E, Moreyra E, Alday LE. Clinical features of hypertrophic cardiomyopathy in the young. Cardiol Young 2002; 12: 147-52.
6. McKenna WJ, Deanfi eld JE. Hypertrophic cardiomyopathy: an important cause of sudden death. Arch Dis Child 1984; 59: 971-75.
7. Schwartz ML, Cox GF, Lin AE, et al. Clinical approach to genetic cardiomyopathy in children. Circulation 1996; 94: 2021-38.
8. Wilkinson JD, Landy DC, Colan SD, et al. The pediatric cardiomyopathy registry and heart failure: key results from the fi rst 15 years. Heart Fail Clin 2010; 6: 401-13.
9. Lipshultz SE, Sleeper LA, Towbin JA, et al. The incidence of pediatric cardiomyopathy in two regions of the United States. N Engl J Med 2003; 348: 1647-55.
10. Nugent AW, Daubeney PEF, Chondros P, et al. The epidemiology of childhood cardiomyopathy in Australia. N Engl J Med 2003; 348: 1639-46.
11. Wilkinson JD, Lowe AM, Salbert BA, et al. Outcomes in children with Noonan syndrome and hypertrophic cardiomyopathy: a study from the Pediatric Cardiomyopathy Registry. Am Heart J 2012; 164: 442-48.
12. Colan SD, Lipshultz SE, Lowe AM, et al. Epidemiology and cause-specifi c outcome of hypertrophic cardiomyopathy in children: fi ndings from the Pediatric Cardiomyopathy Registry. Circulation 2007; 115: 773-81.
13. Yetman AT, Hamilton RM, Benson LN, McCrindle BW. Long-term outcome and prognostic determinants in children with hypertrophic cardiomyopathy. JACC 1998; 32: 1943-50.
14. Maron BJ, Spirito P, Ackerman MJ, et al. Prevention of sudden cardiac death with implantable cardioverter-defi brillators in children and adolescents with hypertrophic cardiomyopathy. J Am Coll Cardiol 2013; 61: 1527-35.
15. Grenier MA, Osganian SK, Cox GF, et al. Design and implementation of the North American Pediatric Cardiomyopathy Registry. Am Heart J 2000; 139: S86-95.
16. Kuczmarski RJ, Ogden CL, Grummer-Strawn LM, et al. CDC growth charts: United States. Adv Data 2000; 314: 1-27.
17. Sluysmans T, Colan SD. Theoretical and empirical derivation of cardiovascular allometric relationships in children. J Appl Physiol 2005; 99: 445-57.
18. Nugent AW, Daubeney PE, Chondros P, et al. Clinical features and outcomes of childhood hypertrophic cardiomyopathy: results from a national population-based study. Circulation 2005; 112: 1332-38.
19. Maskatia SA, Decker JA, Spinner JA, et al. Restrictive physiology is associated with poor outcomes in children with hypertrophic cardiomyopathy. Pediatr Cardiol 2011; 1: 141-49.
20. Gajarski R, Naftel DC, Pahl E, et al. Outcomes of pediatric patients with hypertrophic cardiomyopathy listed for transplant. J Heart Lung Transplant 2009; 28: 1329-34.
21. Ostman-Smith I, Wettrell G, Keeton B, Riesenfeld T, Holmgren D, Ergander U. Echocardiographic and electrocardiographic identifi cation of those children with hypertrophic cardiomyopathy who should be considered at high risk of dying suddenly. Cardiol Young 2005; 15: 632-42.
22. Ragni L, Biagini E, Picchio FM, et al. Heart transplantation in infants with idiopathic hypertrophic cardiomyopathy. Pediatr Transplant 2009; 13: 650-53.
23. Dipchand AI, Naftel DC, Feingold B, et al. Outcomes of children with cardiomyopathy listed for transplant: a multi-institutional study. J Heart Lung Transplant 2009; 28: 1312-21.
24. Decker JA, Rossano JW, Smith EO, et al. Risk factors and mode of death in isolated hypertrophic cardiomyopathy in children. J Am Coll Cardiol 2009; 54: 250-54.
25. Christiaans I, van Engelen K, van Langen IM, et al. Risk stratifi cation for sudden cardiac death in hypertrophic cardiomyopathy: systematic review of clinical risk markers. Europace 2010; 12: 313-21.
26. Sadoul N, de Chillou C, Aliot E, McKenna WJ. Evaluation of the risk of sudden death in hypertrophic cardiomyopathy. Arch Mal Coeur Vaiss 1999; 92: 65-73.
27. Yetman AT, McCrindle BW. Management of pediatric hypertrophic cardiomyopathy. Curr Opin Cardiol 2005; 20: 80-83.
28. Maron MS, Olivotta I, Betocchi S, et al. Eff ect of left ventricular outfl ow tract obstruction on clinical outcome in hypertrophic cardiomyopathy. N Engl J Med 2003; 348: 295-303.
29. Fernández A, Vigliano CA, Casabé JH, et al. Comparison of prevalence, clinical course, and pathological fi ndings of left ventricular systolic impairment versus normal systolic function in patients with hypertrophic cardiomyopathy. Am J Cardiol 2011; 108: 548-55.
30. Altarabsheh SE, Dearani JA, Burkhart HM, et al. Outcome of septal myectomy for obstructive hypertrophic cardiomyopathy in children and young adults. Ann Thorac Surg 2013; 95: 663-69.