A four-week inhalation toxicity study with nylon RFPs in rats: Preliminary findings six months after exposure

Annals of Occupational Hygiene

Volumn 46, Issue , 2002, Pages 173-175

  Warheit, D B ^a   Reed, K L ^a   Webb, T R ^a   Kennedy, G L ^a  

^a DUPONT COMPANY   (United States)

Author keywords

inhalation toxicity; man made organic fibers (MMOF); Nylon RFP; organic fiber types; respirable sized, fiber shaped particulates

Indexed keywords

AEROSOLS; BIOCHEMISTRY; BIOLOGICAL ORGANS; CELL PROLIFERATION; CYTOLOGY; FIBERS; POLYAMIDES; RATS; TOXICITY;

ALVEOLAR MACROPHAGES; FLUID ANALYSIS; HISTOPATHOLOGICAL ANALYSIS; INHALATION TOXICITY; NYLON RFP; ORGANIC FIBERS; RESPIRABLE-SIZED, FIBER-SHAPED PARTICULATES; RESPIRATORY EFFECTS;

RAYON;

EID: 84889167384     PISSN: 00034878     EISSN: 14753162     Source Type: Journal    
DOI: 10.1093/annhyg/46.suppl-1.173     Document Type: Conference Paper

References (3)

1. Porter DW, Castranova V, Robinson VA et al. (1999) Acute inflammation reaction in rats after intratracheal instillation of material collected from a nylon flocking plant. J Toxicol Environ Health; 57: 25-48.
2. Warheit DB, Kellar KA, Hartsky MA. (1992) Pulmonary cellular effects in rats following aerosol exposures to ultrafine Kevlar aramid fibrils: evidence for biodegradability of inhaled fibrils. Toxicol Appl Pharmacol; 116: 225-39.
3. Warheit DB, Hartsky MA, Frame SR. (1996) Pulmonary effects in rats inhaling size-separated chrysotile asbestos fibres or para-aramid fibrils: differences in cellular proliferative responses. Toxicol Lett; 88: 287-92.