Comparison of GnRH agonist and antagonist protocols in normoresponder patients who had IVF-ICSI

Archives of Gynecology and Obstetrics

Volumn 288, Issue 6, 2013, Pages 1413-1416

  Kara, Mustafa ^a   Aydin, Turgut ^b   Aran, Turhan ^c   Turktekin, Nurettin ^d   Ozdemir, Betul ^b  

^a BOZOK UNIVERSITY   (Turkey)

^b Acibadem in Vitro Fertilization Center   (Turkey)

^c KARADENIZ TECHNICAL UNIVERSITY   (Turkey)

^d Kayseri in Vitro Fertilization Centre   (Turkey)

Author keywords

GnRH agonist; GnRH antagonist; IVF ICSI; Pregnancy

Indexed keywords

CHORIONIC GONADOTROPIN; ESTRADIOL; FOLLITROPIN; GONADORELIN AGONIST; GONADORELIN ANTAGONIST; PROGESTERONE;

ADULT; ARTICLE; BLASTOCYST; CLINICAL PROTOCOL; EMBRYO TRANSFER; ESTRADIOL BLOOD LEVEL; FEMALE; FERTILIZATION; FERTILIZATION IN VITRO; FOLLICULAR PHASE; HORMONE DETERMINATION; HUMAN; INTRACYTOPLASMIC SPERM INJECTION; MAJOR CLINICAL STUDY; METAPHASE; NIDATION; PREGNANCY RATE; PROGESTERONE BLOOD LEVEL; WOMEN'S HEALTH;

ADULT; CHORIONIC GONADOTROPIN; CLINICAL PROTOCOLS; DRUG ADMINISTRATION SCHEDULE; ESTRADIOL; ESTROGENS; FEMALE; FERTILIZATION IN VITRO; FOLLICLE STIMULATING HORMONE; GONADOTROPIN-RELEASING HORMONE; HUMANS; INFERTILITY, FEMALE; OOCYTES; PREGNANCY; PREGNANCY RATE; SPERM INJECTIONS, INTRACYTOPLASMIC; TREATMENT OUTCOME;

EID: 84889091026     PISSN: 09320067     EISSN: 14320711     Source Type: Journal    
DOI: 10.1007/s00404-013-2903-z     Document Type: Article

References (17)

1. Fleming R, Adam AH, Barlow DH, Black WP, MacNaughton MC, Coutts JR (1982) A new systematic treatment for infertile women with abnormal hormone profiles. Br J Obstet Gynaecol 89(1):80-83
2. Akman MA, Erden HF, Tosun SB, Bayazit N, Aksoy E, Bahceci M (2001) Comparison of agonistic flare-up-protocol and antagonistic multiple dose protocol in ovarian stimulation of poor responders: results of a prospective randomized trial. Hum Reprod 16(5):868-870
3. Mitwally MFM, Bhakoo HS, Crickard K, Sullivan MW, Batt RE, Yeh J (2006) Estradiol production during controlled ovarian hyperstimulation correlates with treatment outcome in women undergoing in vitro fertilization-embryo transfer. Fertil Steril 86(3):588-596
4. Kara M, Kutlu T, Sofuoglu K, Devranoglu B, Cetinkaya T (2012) Association between serum estradiol level on the hCG administration day and IVF-ICSI outcome. Iranian J Reprod Med 10(1):53-58
5. Nikolettos N, Al-Hasani S, Felberbaum R, Demirel LC, Kupfer W, Montzka P et al (2001) Gonadotropin-releasing hormone antagonist protocol: a novel method of ovarian stimulation in poor responders. Eur J Obstet Gynecol Reprod Biol 97(2):202-207
6. Al-Inany H, Aboulghar M (2002) GnRH antagonist in assisted reproduction. A Cochrane review. Hum Reprod 17(4):874-885
7. Kolibianakis EM, Collins J, Tarlatzis BC, Devroey P, Diedrich K, Griesinger G (2006) Among patients treated for IVF with gonadotrophins and GnRH analogues, is the probability of live birth dependent on the type of analogue used? A systematic review and meta-analysis. Hum Reprod Update 12(6):651-671
8. Al-Inany HG, Youssef MA, Aboulghar M, Broekmans F, Sterrenburg M, Smit J, Abou-Setta AM (2011) GnRH antagonists are safer than agonists: an update of a Cochrane review. Hum Reprod Update 17(4):435
9. Huang SY, Huang HY, Yu HT, Wang HS, Chen CK, Lee CL (2011) Low-dose GnRH antagonist protocol is as effective as the long GnRH agonist protocol in unselected patients undergoing in vitro fertilization and embryo transfer. Taiwan J Obstet Gynecol 50(4):432-435
10. Kara M, Kutlu T, Sofuoglu K (2011) Highly-purified, urinary follicle-stimulating hormone (r-FSH vs. HP-uFSH) in the polycystic ovary syndrom patients who had antagonist cycle with in vitro fertilization-embryo transfer. Turkiye Klinikleri. J Med Sci 31(4):775-779
11. Land JA, Yarmolinskaya MI, Dumoulin JC, Evers JL (1996) High-dose human menopausal gonadotropin stimulation in poor responders does not improve in vitro fertilization outcome. Fertil Steril 65(5):961-965
12. Karande V, Morris R, Rinehart J, Miller C, Rao R, Gleicher N (1997) Limited success using the "flare" protocol in poor responders in cycles with low basal follicle-stimulating hormone levels during in vitro fertilization. Fertil Steril 67(5):900-903
13. Valbuena D, Martin J, de Pablo JL, Remohi J, Pellicer A, Simon C (2001) Increasing levels of estradiol are deleterious to embryonic implantation because they directly affect the embryo. Fertil Steril 76(5):962-968
14. Elnashar AM (2010) Progesterone rise on the day of HCG administration (premature luteinization) in IVF: an overdue update. J Assist Reprod Genet 27(4):149-155
15. Basir GS (2001) O WS, Ng EH, Ho PC. Morphometric analysis of peri-implantation endometrium in patients having excessively high estradiol concentrations after ovarian stimulation. Hum Reprod 16(3):435-440
16. Mangalraj AM, Muthukumar K, Aleyamma T, Kamath MS, George K (2009) Blastocyst stage transfer vs cleavage stage embryo transfer. J Hum Reprod Sci 2(1):23-26
17. Gardner DK, Surrey E, Minjarez D, Leitz A, Stevens J, Schoolcraft WB (2004) Single blastocyst transfer: a prospective randomized trial. Fertil Steril 81(3):551-555