-
1
-
-
34447621808
-
The dioxin (aryl hydrocarbon) receptor as a model for adaptive responses of bHLH/PAS transcription factors
-
Furness,S.G. et al. (2007) The dioxin (aryl hydrocarbon) receptor as a model for adaptive responses of bHLH/PAS transcription factors. FEBS Lett., 581, 3616-3625.
-
(2007)
FEBS Lett.
, vol.581
, pp. 3616-3625
-
-
Furness, S.G.1
-
2
-
-
84886001975
-
The aryl hydrocarbon receptor regulates cell adhesion and migration by interacting with oncogene and growth factor-dependent signaling
-
In Pohjanvirta,R. (ed), John Wiley & Sons, New York, NY
-
Roman,A.C. et al. (2012) The aryl hydrocarbon receptor regulates cell adhesion and migration by interacting with oncogene and growth factor-dependent signaling. In Pohjanvirta,R. (ed) The AH Receptor in Biology and Toxicology. John Wiley & Sons, New York, NY, pp. 485-497.
-
(2012)
The AH Receptor in Biology and Toxicology
-
-
Roman, A.C.1
-
3
-
-
68949172534
-
The aryl hydrocarbon receptor in immunity
-
Esser,C. et al. (2009) The aryl hydrocarbon receptor in immunity. Trends Immunol., 30, 447-454.
-
(2009)
Trends Immunol.
, vol.30
, pp. 447-454
-
-
Esser, C.1
-
4
-
-
34447511096
-
The aryl hydrocarbon receptor, more than a xenobiotic- interacting protein
-
Barouki,R. et al. (2007) The aryl hydrocarbon receptor, more than a xenobiotic- interacting protein. FEBS Lett., 581, 3608-3615.
-
(2007)
FEBS Lett.
, vol.581
, pp. 3608-3615
-
-
Barouki, R.1
-
5
-
-
3142689710
-
A constitutively active dioxin/aryl hydrocarbon receptor promotes hepatocarcinogenesis in mice
-
Moennikes,O. et al. (2004) A constitutively active dioxin/aryl hydrocarbon receptor promotes hepatocarcinogenesis in mice. Cancer Res., 64, 4707-4710.
-
(2004)
Cancer Res.
, vol.64
, pp. 4707-4710
-
-
Moennikes, O.1
-
6
-
-
0037162529
-
A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors
-
Andersson,P. et al. (2002) A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors. Proc. Natl Acad. Sci. USA, 99, 9990-9995.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 9990-9995
-
-
Andersson, P.1
-
7
-
-
75149130980
-
Activation of the aryl-hydrocarbon receptor inhibits invasive and metastatic features of human breast cancer cells and promotes breast cancer cell differentiation
-
Hall,J.M. et al. (2010) Activation of the aryl-hydrocarbon receptor inhibits invasive and metastatic features of human breast cancer cells and promotes breast cancer cell differentiation. Mol. Endocrinol., 24, 359-369.
-
(2010)
Mol. Endocrinol.
, vol.24
, pp. 359-369
-
-
Hall, J.M.1
-
8
-
-
77949351362
-
beta-TrCP inhibition reduces prostate cancer cell growth via upregulation of the aryl hydrocarbon receptor
-
Gluschnaider,U. et al. (2010) beta-TrCP inhibition reduces prostate cancer cell growth via upregulation of the aryl hydrocarbon receptor. PLoS One, 5, e9060.
-
(2010)
PLoS One
, vol.5
-
-
Gluschnaider, U.1
-
9
-
-
75149115740
-
The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis
-
Fan,Y. et al. (2010) The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis. Cancer Res., 70, 212-220.
-
(2010)
Cancer Res.
, vol.70
, pp. 212-220
-
-
Fan, Y.1
-
10
-
-
69449101827
-
Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands
-
Kawajiri,K. et al. (2009) Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands. Proc. Natl Acad. Sci. USA, 106, 13481-13486.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 13481-13486
-
-
Kawajiri, K.1
-
11
-
-
33646192788
-
The dioxin receptor is silenced by promoter hypermethylation in human acute lymphoblastic leukemia through inhibition of Sp1 binding
-
Mulero-Navarro,S. et al. (2006) The dioxin receptor is silenced by promoter hypermethylation in human acute lymphoblastic leukemia through inhibition of Sp1 binding. Carcinogenesis, 27, 1099-1104.
-
(2006)
Carcinogenesis
, vol.27
, pp. 1099-1104
-
-
Mulero-Navarro, S.1
-
12
-
-
65249172049
-
The dioxin receptor regulates the constitutive expression of the vav3 proto-oncogene and modulates cell shape and adhesion
-
Carvajal-Gonzalez,J.M. et al. (2009) The dioxin receptor regulates the constitutive expression of the vav3 proto-oncogene and modulates cell shape and adhesion. Mol. Biol. Cell, 20, 1715-1727.
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 1715-1727
-
-
Carvajal-Gonzalez, J.M.1
-
13
-
-
23344452961
-
Immortalized mouse mammary fibroblasts lacking dioxin receptor have impaired tumorigenicity in a subcutaneous mouse xenograft model
-
Mulero-Navarro,S. et al. (2005) Immortalized mouse mammary fibroblasts lacking dioxin receptor have impaired tumorigenicity in a subcutaneous mouse xenograft model. J. Biol. Chem., 280, 28731-28741.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 28731-28741
-
-
Mulero-Navarro, S.1
-
14
-
-
69949113906
-
Dioxin receptor deficiency impairs angiogenesis by a mechanism involving VEGF-A depletion in the endothelium and transforming growth factor-beta overexpression in the stroma
-
Roman,A.C. et al. (2009) Dioxin receptor deficiency impairs angiogenesis by a mechanism involving VEGF-A depletion in the endothelium and transforming growth factor-beta overexpression in the stroma. J. Biol. Chem., 284, 25135-25148.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 25135-25148
-
-
Roman, A.C.1
-
15
-
-
69449085550
-
Loss of dioxin-receptor expression accelerates wound healing in vivo by a mechanism involving TGFbeta
-
Carvajal-Gonzalez,J.M. et al. (2009) Loss of dioxin-receptor expression accelerates wound healing in vivo by a mechanism involving TGFbeta. J. Cell Sci., 122(Pt 11), 1823-1833.
-
(2009)
J. Cell Sci.
, vol.122
, Issue.PART 11
, pp. 1823-1833
-
-
Carvajal-Gonzalez, J.M.1
-
16
-
-
3042777370
-
The natural course of cutaneous melanoma
-
Leiter,U. et al. (2004) The natural course of cutaneous melanoma. J. Surg. Oncol., 86, 172-178.
-
(2004)
J. Surg. Oncol.
, vol.86
, pp. 172-178
-
-
Leiter, U.1
-
17
-
-
3042666881
-
An evidence-based staging system for cutaneous melanoma
-
quiz 182
-
Balch,C.M. et al. (2004) An evidence-based staging system for cutaneous melanoma. CA. Cancer J. Clin., 54, 131-49; quiz 182.
-
(2004)
CA. Cancer J. Clin.
, vol.54
, pp. 131-49
-
-
Balch, C.M.1
-
18
-
-
84255197842
-
Cancer immunotherapy comes of age
-
Mellman,I. et al. (2011) Cancer immunotherapy comes of age. Nature, 480, 480-489.
-
(2011)
Nature
, vol.480
, pp. 480-489
-
-
Mellman, I.1
-
19
-
-
77958544928
-
Quantitative detection of melanoma-associated antigens by multimarker real-time RT-PCR for molecular staging: results of a 5 years study
-
Gkalpakiotis,S. et al. (2010) Quantitative detection of melanoma-associated antigens by multimarker real-time RT-PCR for molecular staging: results of a 5 years study. Exp. Dermatol., 19, 994-999.
-
(2010)
Exp. Dermatol.
, vol.19
, pp. 994-999
-
-
Gkalpakiotis, S.1
-
20
-
-
79955489170
-
Intra-lymph node prime-boost vaccination against Melan A and tyrosinase for the treatment of metastatic melanoma: results of a phase 1 clinical trial
-
Ribas,A. et al. (2011) Intra-lymph node prime-boost vaccination against Melan A and tyrosinase for the treatment of metastatic melanoma: results of a phase 1 clinical trial. Clin. Cancer Res., 17, 2987-2996.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 2987-2996
-
-
Ribas, A.1
-
21
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies,H. et al. (2002) Mutations of the BRAF gene in human cancer. Nature, 417, 949-954.
-
(2002)
Nature
, vol.417
, pp. 949-954
-
-
Davies, H.1
-
22
-
-
79952072157
-
Transcriptional control of melanoma metastasis: the importance of the tumor microenvironment
-
Braeuer,R.R. et al. (2011) Transcriptional control of melanoma metastasis: the importance of the tumor microenvironment. Semin. Cancer Biol., 21, 83-88.
-
(2011)
Semin. Cancer Biol.
, vol.21
, pp. 83-88
-
-
Braeuer, R.R.1
-
23
-
-
0029000839
-
Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor
-
Fernandez-Salguero,P. et al. (1995) Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor. Science, 268, 722-726.
-
(1995)
Science
, vol.268
, pp. 722-726
-
-
Fernandez-Salguero, P.1
-
24
-
-
84875199673
-
Dioxin receptor expression inhibits basal and transforming growth factor β-induced epithelial-to-mesenchymal transition
-
Rico-Leo,E.M. et al. (2013) Dioxin receptor expression inhibits basal and transforming growth factor β-induced epithelial-to-mesenchymal transition. J. Biol. Chem., 288, 7841-7856.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 7841-7856
-
-
Rico-Leo, E.M.1
-
25
-
-
80052637705
-
Hematopoietic stem cell characterization and isolation
-
Rossi,L. et al. (2011) Hematopoietic stem cell characterization and isolation. Methods Mol. Biol., 750, 47-59.
-
(2011)
Methods Mol. Biol.
, vol.750
, pp. 47-59
-
-
Rossi, L.1
-
26
-
-
84873278890
-
The dioxin receptor controls β1 integrin activation in fibroblasts through a Cbp-Csk-Src pathway
-
Rey-Barroso,J. et al. (2013) The dioxin receptor controls β1 integrin activation in fibroblasts through a Cbp-Csk-Src pathway. Cell Signal., 25, 848-859.
-
(2013)
Cell Signal.
, vol.25
, pp. 848-859
-
-
Rey-Barroso, J.1
-
27
-
-
35649009855
-
E-cadherin is required for caveolin-1-mediated downregulation of the inhibitor of apoptosis protein survivin via reduced betacatenin- Tcf/Lef-dependent transcription
-
Torres,V.A. et al. (2007) E-cadherin is required for caveolin-1-mediated downregulation of the inhibitor of apoptosis protein survivin via reduced betacatenin- Tcf/Lef-dependent transcription. Mol. Cell. Biol., 27, 7703-7717.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 7703-7717
-
-
Torres, V.A.1
-
28
-
-
79952613582
-
Integrins: versatile receptors controlling melanocyte adhesion, migration and proliferation
-
Pinon,P. et al. (2011) Integrins: versatile receptors controlling melanocyte adhesion, migration and proliferation. Pigment Cell Melanoma Res., 24, 282-294.
-
(2011)
Pigment Cell Melanoma Res.
, vol.24
, pp. 282-294
-
-
Pinon, P.1
-
29
-
-
77957339515
-
CAV1 inhibits metastatic potential in melanomas through suppression of the integrin/Src/FAK signaling pathway
-
Trimmer,C. et al. (2010) CAV1 inhibits metastatic potential in melanomas through suppression of the integrin/Src/FAK signaling pathway. Cancer Res., 70, 7489-7499.
-
(2010)
Cancer Res.
, vol.70
, pp. 7489-7499
-
-
Trimmer, C.1
-
30
-
-
78650212925
-
Tenascin-C promotes melanoma progression by maintaining the ABCB5-positive side population
-
Fukunaga-Kalabis,M. et al. (2010) Tenascin-C promotes melanoma progression by maintaining the ABCB5-positive side population. Oncogene, 29, 6115-6124.
-
(2010)
Oncogene
, vol.29
, pp. 6115-6124
-
-
Fukunaga-Kalabis, M.1
-
31
-
-
57349143739
-
Efficient tumour formation by single human melanoma cells
-
Quintana,E. et al. (2008) Efficient tumour formation by single human melanoma cells. Nature, 456, 593-598.
-
(2008)
Nature
, vol.456
, pp. 593-598
-
-
Quintana, E.1
-
32
-
-
36248953716
-
Mammary stem cells and breast cancer-role of Notch signalling
-
Farnie,G. et al. (2007) Mammary stem cells and breast cancer-role of Notch signalling. Stem Cell Rev., 3, 169-175.
-
(2007)
Stem Cell Rev.
, vol.3
, pp. 169-175
-
-
Farnie, G.1
-
34
-
-
33846913663
-
E-cadherin and beta-catenin expression patterns in malignant melanoma assessed by image analysis
-
Pecina-Slaus,N. et al. (2007) E-cadherin and beta-catenin expression patterns in malignant melanoma assessed by image analysis. J. Cutan. Pathol., 34, 239-246.
-
(2007)
J. Cutan. Pathol.
, vol.34
, pp. 239-246
-
-
Pecina-Slaus, N.1
-
35
-
-
36149001019
-
Involvement of E-cadherin, beta-catenin, Cdc42 and CXCR4 in the progression and prognosis of cutaneous melanoma
-
Tucci,M.G. et al. (2007) Involvement of E-cadherin, beta-catenin, Cdc42 and CXCR4 in the progression and prognosis of cutaneous melanoma. Br. J. Dermatol., 157, 1212-1216.
-
(2007)
Br. J. Dermatol.
, vol.157
, pp. 1212-1216
-
-
Tucci, M.G.1
-
36
-
-
84860508683
-
Genetic ablation of Cav1 differentially affects melanoma tumor growth and metastasis in mice: role of Cav1 in Shh heterotypic signaling and transendothelial migration
-
Capozza,F. et al. (2012) Genetic ablation of Cav1 differentially affects melanoma tumor growth and metastasis in mice: role of Cav1 in Shh heterotypic signaling and transendothelial migration. Cancer Res., 72, 2262-2274.
-
(2012)
Cancer Res.
, vol.72
, pp. 2262-2274
-
-
Capozza, F.1
-
37
-
-
84859598348
-
Caveolin-1-enhanced motility and focal adhesion turnover require tyrosine-14 but not accumulation to the rear in metastatic cancer cells
-
Urra,H. et al. (2012) Caveolin-1-enhanced motility and focal adhesion turnover require tyrosine-14 but not accumulation to the rear in metastatic cancer cells. PLoS One, 7, e33085.
-
(2012)
PLoS One
, vol.7
-
-
Urra, H.1
-
38
-
-
84857118750
-
The interaction between caveolin-1 and Rho- GTPases promotes metastasis by controlling the expression of alpha5- integrin and the activation of Src, Ras and Erk
-
Arpaia,E. et al. (2012) The interaction between caveolin-1 and Rho- GTPases promotes metastasis by controlling the expression of alpha5- integrin and the activation of Src, Ras and Erk. Oncogene, 31, 884-896.
-
(2012)
Oncogene
, vol.31
, pp. 884-896
-
-
Arpaia, E.1
-
39
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery,J.P. et al. (2009) Epithelial-mesenchymal transitions in development and disease. Cell, 139, 871-890.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
-
40
-
-
84856594204
-
Activation of the aryl hydrocarbon receptor represses mammosphere formation in MCF-7 cells
-
Zhao,S. et al. (2012) Activation of the aryl hydrocarbon receptor represses mammosphere formation in MCF-7 cells. Cancer Lett., 317, 192-198.
-
(2012)
Cancer Lett.
, vol.317
, pp. 192-198
-
-
Zhao, S.1
-
41
-
-
77956519710
-
Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells
-
Boitano,A.E. et al. (2010) Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells. Science, 329, 1345-1348.
-
(2010)
Science
, vol.329
, pp. 1345-1348
-
-
Boitano, A.E.1
-
42
-
-
59149093814
-
Fitting a xenobiotic receptor into cell homeostasis: how the dioxin receptor interacts with TGFbeta signaling
-
Gomez-Duran,A. et al. (2009) Fitting a xenobiotic receptor into cell homeostasis: how the dioxin receptor interacts with TGFbeta signaling. Biochem. Pharmacol., 77, 700-712.
-
(2009)
Biochem. Pharmacol.
, vol.77
, pp. 700-712
-
-
Gomez-Duran, A.1
-
43
-
-
84864285794
-
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
-
Straussman,R. et al. (2012) Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion. Nature, 487, 500-504.
-
(2012)
Nature
, vol.487
, pp. 500-504
-
-
Straussman, R.1
-
44
-
-
42649095378
-
Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor
-
Quintana,F.J. et al. (2008) Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor. Nature, 453, 65-71.
-
(2008)
Nature
, vol.453
, pp. 65-71
-
-
Quintana, F.J.1
-
45
-
-
42649106556
-
The aryl hydrocarbon receptor links TH17-cellmediated autoimmunity to environmental toxins
-
Veldhoen,M. et al. (2008) The aryl hydrocarbon receptor links TH17-cellmediated autoimmunity to environmental toxins. Nature, 453, 106-109.
-
(2008)
Nature
, vol.453
, pp. 106-109
-
-
Veldhoen, M.1
-
46
-
-
84868220730
-
Tryptophan catabolism in cancer: beyond IDO and tryptophan depletion
-
Platten,M. et al. (2012) Tryptophan catabolism in cancer: beyond IDO and tryptophan depletion. Cancer Res., 72, 5435-5440.
-
(2012)
Cancer Res.
, vol.72
, pp. 5435-5440
-
-
Platten, M.1
-
47
-
-
84869212634
-
The kynurenine pathway in brain tumor pathogenesis
-
Adams,S. et al. (2012) The kynurenine pathway in brain tumor pathogenesis. Cancer Res., 72, 5649-5657.
-
(2012)
Cancer Res.
, vol.72
, pp. 5649-5657
-
-
Adams, S.1
-
48
-
-
12244269085
-
Characterization of in vitro metabolites of the aryl hydrocarbon receptor ligand 6-formylindolo[3,2-b]carbazole by liquid chromatography-mass spectrometry and NMR
-
Bergander,L. et al. (2003) Characterization of in vitro metabolites of the aryl hydrocarbon receptor ligand 6-formylindolo[3,2-b]carbazole by liquid chromatography-mass spectrometry and NMR. Drug Metab. Dispos., 31, 233-241.
-
(2003)
Drug Metab. Dispos.
, vol.31
, pp. 233-241
-
-
Bergander, L.1
-
49
-
-
81855190624
-
Activation of the aryl hydrocarbon receptor by TCDD inhibits mammary tumor metastasis in a syngeneic mouse model of breast cancer
-
Wang,T. et al. (2011) Activation of the aryl hydrocarbon receptor by TCDD inhibits mammary tumor metastasis in a syngeneic mouse model of breast cancer. Toxicol. Sci., 124, 291-298.
-
(2011)
Toxicol. Sci.
, vol.124
, pp. 291-298
-
-
Wang, T.1
|