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Volumn 34, Issue 12, 2013, Pages 2683-2693

The dioxin receptor has tumor suppressor activity in melanoma growth and metastasis

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; BETA1 INTEGRIN; CAVEOLIN 1; MOLECULAR MARKER; SHORT HAIRPIN RNA;

EID: 84889072389     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgt248     Document Type: Article
Times cited : (61)

References (49)
  • 1
    • 34447621808 scopus 로고    scopus 로고
    • The dioxin (aryl hydrocarbon) receptor as a model for adaptive responses of bHLH/PAS transcription factors
    • Furness,S.G. et al. (2007) The dioxin (aryl hydrocarbon) receptor as a model for adaptive responses of bHLH/PAS transcription factors. FEBS Lett., 581, 3616-3625.
    • (2007) FEBS Lett. , vol.581 , pp. 3616-3625
    • Furness, S.G.1
  • 2
    • 84886001975 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor regulates cell adhesion and migration by interacting with oncogene and growth factor-dependent signaling
    • In Pohjanvirta,R. (ed), John Wiley & Sons, New York, NY
    • Roman,A.C. et al. (2012) The aryl hydrocarbon receptor regulates cell adhesion and migration by interacting with oncogene and growth factor-dependent signaling. In Pohjanvirta,R. (ed) The AH Receptor in Biology and Toxicology. John Wiley & Sons, New York, NY, pp. 485-497.
    • (2012) The AH Receptor in Biology and Toxicology
    • Roman, A.C.1
  • 3
    • 68949172534 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor in immunity
    • Esser,C. et al. (2009) The aryl hydrocarbon receptor in immunity. Trends Immunol., 30, 447-454.
    • (2009) Trends Immunol. , vol.30 , pp. 447-454
    • Esser, C.1
  • 4
    • 34447511096 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor, more than a xenobiotic- interacting protein
    • Barouki,R. et al. (2007) The aryl hydrocarbon receptor, more than a xenobiotic- interacting protein. FEBS Lett., 581, 3608-3615.
    • (2007) FEBS Lett. , vol.581 , pp. 3608-3615
    • Barouki, R.1
  • 5
    • 3142689710 scopus 로고    scopus 로고
    • A constitutively active dioxin/aryl hydrocarbon receptor promotes hepatocarcinogenesis in mice
    • Moennikes,O. et al. (2004) A constitutively active dioxin/aryl hydrocarbon receptor promotes hepatocarcinogenesis in mice. Cancer Res., 64, 4707-4710.
    • (2004) Cancer Res. , vol.64 , pp. 4707-4710
    • Moennikes, O.1
  • 6
    • 0037162529 scopus 로고    scopus 로고
    • A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors
    • Andersson,P. et al. (2002) A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors. Proc. Natl Acad. Sci. USA, 99, 9990-9995.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 9990-9995
    • Andersson, P.1
  • 7
    • 75149130980 scopus 로고    scopus 로고
    • Activation of the aryl-hydrocarbon receptor inhibits invasive and metastatic features of human breast cancer cells and promotes breast cancer cell differentiation
    • Hall,J.M. et al. (2010) Activation of the aryl-hydrocarbon receptor inhibits invasive and metastatic features of human breast cancer cells and promotes breast cancer cell differentiation. Mol. Endocrinol., 24, 359-369.
    • (2010) Mol. Endocrinol. , vol.24 , pp. 359-369
    • Hall, J.M.1
  • 8
    • 77949351362 scopus 로고    scopus 로고
    • beta-TrCP inhibition reduces prostate cancer cell growth via upregulation of the aryl hydrocarbon receptor
    • Gluschnaider,U. et al. (2010) beta-TrCP inhibition reduces prostate cancer cell growth via upregulation of the aryl hydrocarbon receptor. PLoS One, 5, e9060.
    • (2010) PLoS One , vol.5
    • Gluschnaider, U.1
  • 9
    • 75149115740 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis
    • Fan,Y. et al. (2010) The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis. Cancer Res., 70, 212-220.
    • (2010) Cancer Res. , vol.70 , pp. 212-220
    • Fan, Y.1
  • 10
    • 69449101827 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands
    • Kawajiri,K. et al. (2009) Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands. Proc. Natl Acad. Sci. USA, 106, 13481-13486.
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 13481-13486
    • Kawajiri, K.1
  • 11
    • 33646192788 scopus 로고    scopus 로고
    • The dioxin receptor is silenced by promoter hypermethylation in human acute lymphoblastic leukemia through inhibition of Sp1 binding
    • Mulero-Navarro,S. et al. (2006) The dioxin receptor is silenced by promoter hypermethylation in human acute lymphoblastic leukemia through inhibition of Sp1 binding. Carcinogenesis, 27, 1099-1104.
    • (2006) Carcinogenesis , vol.27 , pp. 1099-1104
    • Mulero-Navarro, S.1
  • 12
    • 65249172049 scopus 로고    scopus 로고
    • The dioxin receptor regulates the constitutive expression of the vav3 proto-oncogene and modulates cell shape and adhesion
    • Carvajal-Gonzalez,J.M. et al. (2009) The dioxin receptor regulates the constitutive expression of the vav3 proto-oncogene and modulates cell shape and adhesion. Mol. Biol. Cell, 20, 1715-1727.
    • (2009) Mol. Biol. Cell , vol.20 , pp. 1715-1727
    • Carvajal-Gonzalez, J.M.1
  • 13
    • 23344452961 scopus 로고    scopus 로고
    • Immortalized mouse mammary fibroblasts lacking dioxin receptor have impaired tumorigenicity in a subcutaneous mouse xenograft model
    • Mulero-Navarro,S. et al. (2005) Immortalized mouse mammary fibroblasts lacking dioxin receptor have impaired tumorigenicity in a subcutaneous mouse xenograft model. J. Biol. Chem., 280, 28731-28741.
    • (2005) J. Biol. Chem. , vol.280 , pp. 28731-28741
    • Mulero-Navarro, S.1
  • 14
    • 69949113906 scopus 로고    scopus 로고
    • Dioxin receptor deficiency impairs angiogenesis by a mechanism involving VEGF-A depletion in the endothelium and transforming growth factor-beta overexpression in the stroma
    • Roman,A.C. et al. (2009) Dioxin receptor deficiency impairs angiogenesis by a mechanism involving VEGF-A depletion in the endothelium and transforming growth factor-beta overexpression in the stroma. J. Biol. Chem., 284, 25135-25148.
    • (2009) J. Biol. Chem. , vol.284 , pp. 25135-25148
    • Roman, A.C.1
  • 15
    • 69449085550 scopus 로고    scopus 로고
    • Loss of dioxin-receptor expression accelerates wound healing in vivo by a mechanism involving TGFbeta
    • Carvajal-Gonzalez,J.M. et al. (2009) Loss of dioxin-receptor expression accelerates wound healing in vivo by a mechanism involving TGFbeta. J. Cell Sci., 122(Pt 11), 1823-1833.
    • (2009) J. Cell Sci. , vol.122 , Issue.PART 11 , pp. 1823-1833
    • Carvajal-Gonzalez, J.M.1
  • 16
    • 3042777370 scopus 로고    scopus 로고
    • The natural course of cutaneous melanoma
    • Leiter,U. et al. (2004) The natural course of cutaneous melanoma. J. Surg. Oncol., 86, 172-178.
    • (2004) J. Surg. Oncol. , vol.86 , pp. 172-178
    • Leiter, U.1
  • 17
    • 3042666881 scopus 로고    scopus 로고
    • An evidence-based staging system for cutaneous melanoma
    • quiz 182
    • Balch,C.M. et al. (2004) An evidence-based staging system for cutaneous melanoma. CA. Cancer J. Clin., 54, 131-49; quiz 182.
    • (2004) CA. Cancer J. Clin. , vol.54 , pp. 131-49
    • Balch, C.M.1
  • 18
    • 84255197842 scopus 로고    scopus 로고
    • Cancer immunotherapy comes of age
    • Mellman,I. et al. (2011) Cancer immunotherapy comes of age. Nature, 480, 480-489.
    • (2011) Nature , vol.480 , pp. 480-489
    • Mellman, I.1
  • 19
    • 77958544928 scopus 로고    scopus 로고
    • Quantitative detection of melanoma-associated antigens by multimarker real-time RT-PCR for molecular staging: results of a 5 years study
    • Gkalpakiotis,S. et al. (2010) Quantitative detection of melanoma-associated antigens by multimarker real-time RT-PCR for molecular staging: results of a 5 years study. Exp. Dermatol., 19, 994-999.
    • (2010) Exp. Dermatol. , vol.19 , pp. 994-999
    • Gkalpakiotis, S.1
  • 20
    • 79955489170 scopus 로고    scopus 로고
    • Intra-lymph node prime-boost vaccination against Melan A and tyrosinase for the treatment of metastatic melanoma: results of a phase 1 clinical trial
    • Ribas,A. et al. (2011) Intra-lymph node prime-boost vaccination against Melan A and tyrosinase for the treatment of metastatic melanoma: results of a phase 1 clinical trial. Clin. Cancer Res., 17, 2987-2996.
    • (2011) Clin. Cancer Res. , vol.17 , pp. 2987-2996
    • Ribas, A.1
  • 21
    • 18444374405 scopus 로고    scopus 로고
    • Mutations of the BRAF gene in human cancer
    • Davies,H. et al. (2002) Mutations of the BRAF gene in human cancer. Nature, 417, 949-954.
    • (2002) Nature , vol.417 , pp. 949-954
    • Davies, H.1
  • 22
    • 79952072157 scopus 로고    scopus 로고
    • Transcriptional control of melanoma metastasis: the importance of the tumor microenvironment
    • Braeuer,R.R. et al. (2011) Transcriptional control of melanoma metastasis: the importance of the tumor microenvironment. Semin. Cancer Biol., 21, 83-88.
    • (2011) Semin. Cancer Biol. , vol.21 , pp. 83-88
    • Braeuer, R.R.1
  • 23
    • 0029000839 scopus 로고
    • Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor
    • Fernandez-Salguero,P. et al. (1995) Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor. Science, 268, 722-726.
    • (1995) Science , vol.268 , pp. 722-726
    • Fernandez-Salguero, P.1
  • 24
    • 84875199673 scopus 로고    scopus 로고
    • Dioxin receptor expression inhibits basal and transforming growth factor β-induced epithelial-to-mesenchymal transition
    • Rico-Leo,E.M. et al. (2013) Dioxin receptor expression inhibits basal and transforming growth factor β-induced epithelial-to-mesenchymal transition. J. Biol. Chem., 288, 7841-7856.
    • (2013) J. Biol. Chem. , vol.288 , pp. 7841-7856
    • Rico-Leo, E.M.1
  • 25
    • 80052637705 scopus 로고    scopus 로고
    • Hematopoietic stem cell characterization and isolation
    • Rossi,L. et al. (2011) Hematopoietic stem cell characterization and isolation. Methods Mol. Biol., 750, 47-59.
    • (2011) Methods Mol. Biol. , vol.750 , pp. 47-59
    • Rossi, L.1
  • 26
    • 84873278890 scopus 로고    scopus 로고
    • The dioxin receptor controls β1 integrin activation in fibroblasts through a Cbp-Csk-Src pathway
    • Rey-Barroso,J. et al. (2013) The dioxin receptor controls β1 integrin activation in fibroblasts through a Cbp-Csk-Src pathway. Cell Signal., 25, 848-859.
    • (2013) Cell Signal. , vol.25 , pp. 848-859
    • Rey-Barroso, J.1
  • 27
    • 35649009855 scopus 로고    scopus 로고
    • E-cadherin is required for caveolin-1-mediated downregulation of the inhibitor of apoptosis protein survivin via reduced betacatenin- Tcf/Lef-dependent transcription
    • Torres,V.A. et al. (2007) E-cadherin is required for caveolin-1-mediated downregulation of the inhibitor of apoptosis protein survivin via reduced betacatenin- Tcf/Lef-dependent transcription. Mol. Cell. Biol., 27, 7703-7717.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 7703-7717
    • Torres, V.A.1
  • 28
    • 79952613582 scopus 로고    scopus 로고
    • Integrins: versatile receptors controlling melanocyte adhesion, migration and proliferation
    • Pinon,P. et al. (2011) Integrins: versatile receptors controlling melanocyte adhesion, migration and proliferation. Pigment Cell Melanoma Res., 24, 282-294.
    • (2011) Pigment Cell Melanoma Res. , vol.24 , pp. 282-294
    • Pinon, P.1
  • 29
    • 77957339515 scopus 로고    scopus 로고
    • CAV1 inhibits metastatic potential in melanomas through suppression of the integrin/Src/FAK signaling pathway
    • Trimmer,C. et al. (2010) CAV1 inhibits metastatic potential in melanomas through suppression of the integrin/Src/FAK signaling pathway. Cancer Res., 70, 7489-7499.
    • (2010) Cancer Res. , vol.70 , pp. 7489-7499
    • Trimmer, C.1
  • 30
    • 78650212925 scopus 로고    scopus 로고
    • Tenascin-C promotes melanoma progression by maintaining the ABCB5-positive side population
    • Fukunaga-Kalabis,M. et al. (2010) Tenascin-C promotes melanoma progression by maintaining the ABCB5-positive side population. Oncogene, 29, 6115-6124.
    • (2010) Oncogene , vol.29 , pp. 6115-6124
    • Fukunaga-Kalabis, M.1
  • 31
    • 57349143739 scopus 로고    scopus 로고
    • Efficient tumour formation by single human melanoma cells
    • Quintana,E. et al. (2008) Efficient tumour formation by single human melanoma cells. Nature, 456, 593-598.
    • (2008) Nature , vol.456 , pp. 593-598
    • Quintana, E.1
  • 32
    • 36248953716 scopus 로고    scopus 로고
    • Mammary stem cells and breast cancer-role of Notch signalling
    • Farnie,G. et al. (2007) Mammary stem cells and breast cancer-role of Notch signalling. Stem Cell Rev., 3, 169-175.
    • (2007) Stem Cell Rev. , vol.3 , pp. 169-175
    • Farnie, G.1
  • 34
    • 33846913663 scopus 로고    scopus 로고
    • E-cadherin and beta-catenin expression patterns in malignant melanoma assessed by image analysis
    • Pecina-Slaus,N. et al. (2007) E-cadherin and beta-catenin expression patterns in malignant melanoma assessed by image analysis. J. Cutan. Pathol., 34, 239-246.
    • (2007) J. Cutan. Pathol. , vol.34 , pp. 239-246
    • Pecina-Slaus, N.1
  • 35
    • 36149001019 scopus 로고    scopus 로고
    • Involvement of E-cadherin, beta-catenin, Cdc42 and CXCR4 in the progression and prognosis of cutaneous melanoma
    • Tucci,M.G. et al. (2007) Involvement of E-cadherin, beta-catenin, Cdc42 and CXCR4 in the progression and prognosis of cutaneous melanoma. Br. J. Dermatol., 157, 1212-1216.
    • (2007) Br. J. Dermatol. , vol.157 , pp. 1212-1216
    • Tucci, M.G.1
  • 36
    • 84860508683 scopus 로고    scopus 로고
    • Genetic ablation of Cav1 differentially affects melanoma tumor growth and metastasis in mice: role of Cav1 in Shh heterotypic signaling and transendothelial migration
    • Capozza,F. et al. (2012) Genetic ablation of Cav1 differentially affects melanoma tumor growth and metastasis in mice: role of Cav1 in Shh heterotypic signaling and transendothelial migration. Cancer Res., 72, 2262-2274.
    • (2012) Cancer Res. , vol.72 , pp. 2262-2274
    • Capozza, F.1
  • 37
    • 84859598348 scopus 로고    scopus 로고
    • Caveolin-1-enhanced motility and focal adhesion turnover require tyrosine-14 but not accumulation to the rear in metastatic cancer cells
    • Urra,H. et al. (2012) Caveolin-1-enhanced motility and focal adhesion turnover require tyrosine-14 but not accumulation to the rear in metastatic cancer cells. PLoS One, 7, e33085.
    • (2012) PLoS One , vol.7
    • Urra, H.1
  • 38
    • 84857118750 scopus 로고    scopus 로고
    • The interaction between caveolin-1 and Rho- GTPases promotes metastasis by controlling the expression of alpha5- integrin and the activation of Src, Ras and Erk
    • Arpaia,E. et al. (2012) The interaction between caveolin-1 and Rho- GTPases promotes metastasis by controlling the expression of alpha5- integrin and the activation of Src, Ras and Erk. Oncogene, 31, 884-896.
    • (2012) Oncogene , vol.31 , pp. 884-896
    • Arpaia, E.1
  • 39
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery,J.P. et al. (2009) Epithelial-mesenchymal transitions in development and disease. Cell, 139, 871-890.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1
  • 40
    • 84856594204 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor represses mammosphere formation in MCF-7 cells
    • Zhao,S. et al. (2012) Activation of the aryl hydrocarbon receptor represses mammosphere formation in MCF-7 cells. Cancer Lett., 317, 192-198.
    • (2012) Cancer Lett. , vol.317 , pp. 192-198
    • Zhao, S.1
  • 41
    • 77956519710 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells
    • Boitano,A.E. et al. (2010) Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells. Science, 329, 1345-1348.
    • (2010) Science , vol.329 , pp. 1345-1348
    • Boitano, A.E.1
  • 42
    • 59149093814 scopus 로고    scopus 로고
    • Fitting a xenobiotic receptor into cell homeostasis: how the dioxin receptor interacts with TGFbeta signaling
    • Gomez-Duran,A. et al. (2009) Fitting a xenobiotic receptor into cell homeostasis: how the dioxin receptor interacts with TGFbeta signaling. Biochem. Pharmacol., 77, 700-712.
    • (2009) Biochem. Pharmacol. , vol.77 , pp. 700-712
    • Gomez-Duran, A.1
  • 43
    • 84864285794 scopus 로고    scopus 로고
    • Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
    • Straussman,R. et al. (2012) Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion. Nature, 487, 500-504.
    • (2012) Nature , vol.487 , pp. 500-504
    • Straussman, R.1
  • 44
    • 42649095378 scopus 로고    scopus 로고
    • Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor
    • Quintana,F.J. et al. (2008) Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor. Nature, 453, 65-71.
    • (2008) Nature , vol.453 , pp. 65-71
    • Quintana, F.J.1
  • 45
    • 42649106556 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor links TH17-cellmediated autoimmunity to environmental toxins
    • Veldhoen,M. et al. (2008) The aryl hydrocarbon receptor links TH17-cellmediated autoimmunity to environmental toxins. Nature, 453, 106-109.
    • (2008) Nature , vol.453 , pp. 106-109
    • Veldhoen, M.1
  • 46
    • 84868220730 scopus 로고    scopus 로고
    • Tryptophan catabolism in cancer: beyond IDO and tryptophan depletion
    • Platten,M. et al. (2012) Tryptophan catabolism in cancer: beyond IDO and tryptophan depletion. Cancer Res., 72, 5435-5440.
    • (2012) Cancer Res. , vol.72 , pp. 5435-5440
    • Platten, M.1
  • 47
    • 84869212634 scopus 로고    scopus 로고
    • The kynurenine pathway in brain tumor pathogenesis
    • Adams,S. et al. (2012) The kynurenine pathway in brain tumor pathogenesis. Cancer Res., 72, 5649-5657.
    • (2012) Cancer Res. , vol.72 , pp. 5649-5657
    • Adams, S.1
  • 48
    • 12244269085 scopus 로고    scopus 로고
    • Characterization of in vitro metabolites of the aryl hydrocarbon receptor ligand 6-formylindolo[3,2-b]carbazole by liquid chromatography-mass spectrometry and NMR
    • Bergander,L. et al. (2003) Characterization of in vitro metabolites of the aryl hydrocarbon receptor ligand 6-formylindolo[3,2-b]carbazole by liquid chromatography-mass spectrometry and NMR. Drug Metab. Dispos., 31, 233-241.
    • (2003) Drug Metab. Dispos. , vol.31 , pp. 233-241
    • Bergander, L.1
  • 49
    • 81855190624 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor by TCDD inhibits mammary tumor metastasis in a syngeneic mouse model of breast cancer
    • Wang,T. et al. (2011) Activation of the aryl hydrocarbon receptor by TCDD inhibits mammary tumor metastasis in a syngeneic mouse model of breast cancer. Toxicol. Sci., 124, 291-298.
    • (2011) Toxicol. Sci. , vol.124 , pp. 291-298
    • Wang, T.1


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