Enhanced oval window and blocked round window passages for middle–inner ear transportation of gadolinium in guinea pigs with a perforated round window membrane

European Archives of Oto-Rhino-Laryngology

Volumn 272, Issue 2, 2015, Pages 303-309

  Zou, Jing ^a,b   Pyykkö, Ilmari ^a  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Animal; Contrast agent; Hydrodynamics; MRI; Oval window; Perilymph; Perilymphatic fistula; Radial communication

Indexed keywords

CONTRAST MEDIUM; GADOLINIUM PENTETATE;

ANIMAL; ANIMAL MODEL; COCHLEA; COCHLEA FENESTRA; GUINEA PIG; INJURIES; INNER EAR; METABOLISM; PERILYMPH; PERMEABILITY; VESTIBULE;

ANIMALS; COCHLEA; CONTRAST MEDIA; EAR, INNER; GADOLINIUM DTPA; GUINEA PIGS; MODELS, ANIMAL; OVAL WINDOW, EAR; PERILYMPH; PERMEABILITY; ROUND WINDOW, EAR;

EID: 84889042669     PISSN: 09374477     EISSN: 14344726     Source Type: Journal    
DOI: 10.1007/s00405-013-2856-7     Document Type: Article

References (19)

1. Paparella MM, Schachern PA, Goycoolea MV (1988) Perilymphatic hypertension. Otolaryngol Head Neck Surg 99:408–413
2. Ikezono T, Shindo S, Sekine K, Shiiba K, Matsuda H, Kusama K, Koizumi Y, Sugizaki K, Sekiguchi S, Kataoka R, Pawankar R, Baba S, Yagi T, Okubo K (2011) Cochlin-tomoprotein (CTP) detection test identifies traumatic perilymphatic fistula due to penetrating middle ear injury. Acta Otolaryngol 131:937–944
3. Weber PC, Perez BA, Bluestone CD (1993) Congenital perilymphatic fistula and associated middle ear abnormalities. Laryngoscope 103:160–164
4. Al Felasi M, Pierre G, Mondain M, Uziel A, Venail F (2011) Perilymphatic fistula of the round window. Eur Ann Otorhinolaryngol Head Neck Dis 128:139–141
5. Fitzgerald DC (2001) Perilymphatic fistula and Meniere’s disease. Clinical series and literature review. Ann Otol Rhinol Laryngol 110:430–436
6. Haubner F, Rohrmeier C, Koch C, Vielsmeier V, Strutz J, Kleinjung T (2012) Occurence of a round window membrane rupture in patients with sudden sensorineural hearing loss. BMC Ear Nose Throat Disord 12:14
7. Goodman PM, Morioka WT (1978) Round window membrane rupture. Laryngoscope 88(383–8):97
8. Goodhill V (1980) Traumatic fistulae. J Laryngol Otol 94:123–128
9. Flood LM, Fraser JG, Hazell JW, Rothera MP (1985) Perilymph fistula. Four year experience with a new audiometric test. J Laryngol Otol 99:671–676
10. Morris MS, Kil J, Carvlin MJ (1993) Magnetic resonance imaging of perilymphatic fistula. Laryngoscope 103:729–733
11. Algin O, Bercin S, Akgunduz G, Turkbey B, Cetin H (2012) Evaluation of labyrinthine fistula by MR cisternography. Emerg Radiol 19:557–560
12. Rask-Andersen H, Schrott-Fischer A, Pfaller K, Glueckert R (2006) Perilymph/modiolar communication routes in the human cochlea. Ear Hear 27:457–465
13. Wlodyka J (1978) Studies on cochlear aqueduct patency. Ann Otol Rhinol Laryngol 87:22–28
14. Zou J, Pyykko I, Counter SA, Klason T, Bretlau P, Bjelke B (2003) In vivo observation of dynamic perilymph formation using 4.7 T MRI with gadolinium as a tracer. Acta Otolaryngol 123:910–915
15. Mark AS, Fitzgerald D (1993) Segmental enhancement of the cochlea on contrast-enhanced MR: correlation with the frequency of hearing loss and possible sign of perilymphatic fistula and autoimmune labyrinthitis. AJNR Am J Neuroradiol 14:991–996
16. Counter SA, Zou J, Bjelke B, Klason T (2003) 3D MRI of the in vivo vestibulo-cochlea labyrinth during Gd-DTPA-BMA uptake. Neuroreport 14:1707–1712
17. Zou J, Pyykko I, Bjelke B, Dastidar P, Toppila E (2005) Communication between the perilymphatic scalae and spiral ligament visualized by in vivo MRI. Audiol Neurootol 10:145–152
18. Zou J, Poe D, Ramadan UA, Pyykko I (2012) Oval window transport of Gd-dOTA from rat middle ear to vestibulum and scala vestibuli visualized by in vivo magnetic resonance imaging. Ann Otol Rhinol Laryngol 121:119–128
19. Shi H, Li Y, Yin S, Zou J (2013) Predominant vestibular uptake of gadolinium through the oval window pathway is compromised by endolymphatic hydrops in Meniere’s disease. Otol Neurotol. doi:10.1097/MAO.0000000000000196 [Epub ahead of print]