Asymmetric dimethylarginine blocks nitric oxide-mediated alcohol-stimulated cilia beating

Mediators of Inflammation

Volumn 2013, Issue , 2013, Pages

  Wyatt, T A ^a,b,c   Wells, S M ^b   Alsaidi, Z A ^c   Devasure, J M ^c   Klein, E B ^c   Bailey, K L ^a,c   Sisson, J H ^c  

^a VA NEBRASKA WESTERN IOWA HEALTH CARE SYSTEM   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c Pulmonary Critical Care Sleep and Allergy Section   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; CYCLIC AMP DEPENDENT PROTEIN KINASE; DIMETHYLARGININASE; N(G),N(G) DIMETHYLARGININE; NITRIC OXIDE; AMIDASE; ARGININE; DRUG DERIVATIVE; N,N DIMETHYLARGININE; N,N-DIMETHYLARGININE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CILIA BEAT FREQUENCY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; EPITHELIUM CELL; EUKARYOTIC FLAGELLUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT PARAMETERS; ANIMAL; BRONCHUS; C57BL MOUSE; CATTLE; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DRUG EFFECT; LUNG; LUNG DISEASE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; TIME; TRACHEA; TRANSGENIC MOUSE;

BOVINAE; MUS;

AMIDOHYDROLASES; ANIMALS; ARGININE; BRONCHI; CATTLE; CELL SURVIVAL; CELLS, CULTURED; CILIA; CYCLIC AMP-DEPENDENT PROTEIN KINASES; EPITHELIAL CELLS; ETHANOL; LUNG; LUNG DISEASES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NITRIC OXIDE; TIME FACTORS; TRACHEA;

EID: 84888984828     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2013/592892     Document Type: Article

References (36)

1. Sisson J. H., Alcohol and airways function in health and disease. Alcohol 2007 41 5 293 307 2-s2.0-34548783829 10.1016/j.alcohol.2007.06.003 (Pubitemid 47432742)
2. Moss M., Burnham E. L., Chronic alcohol abuse, acute respiratory distress syndrome, and multiple organ dysfunction. Critical Care Medicine 2003 31 4, supplement S207 S212 2-s2.0-0037394512 (Pubitemid 36458169)
3. Happel K. I., Nelson S., Alcohol, immunosuppression, and the lung. Proceedings of the American Thoracic Society 2005 2 5 428 432 2-s2.0-31144470448 10.1513/pats.200507-065JS (Pubitemid 43128038)
4. Kershaw C. D., Guidot D. M., Alcoholic lung disease. Alcohol Research and Health 2008 31 1 66 75 2-s2.0-45349100940
5. Hlastala M. P., The alcohol breath test-a review. Journal of Applied Physiology 1998 84 2 401 408 2-s2.0-0031915856 (Pubitemid 28081087)
6. Wyatt T. A., Forgèt M. A., Adams J. M., Sisson J. H., Both cAMP and cGMP are required for maximal ciliary beat stimulation in a cell-free model of bovine ciliary axonemes. American Journal of Physiology-Lung Cellular and Molecular Physiology 2005 288 3 L546 L551 2-s2.0-13644257563 10.1152/ajplung.00107.2004 (Pubitemid 40229521)
7. Sisson J. H., Ethanol stimulates apparent nitric oxide-dependent ciliary beat frequency in bovine airway epithelial cells. American Journal of Physiology-Lung Cellular and Molecular Physiology 1995 268 4, part 1 L596 L600 2-s2.0-0028911219
8. Jain B., Rubinstein I., Robbins R. A., Sisson J. H., TNF- α and IL-1 β upregulate nitric oxide-dependent ciliary motility in bovine airway epithelium. American Journal of Physiology-Lung Cellular and Molecular Physiology 1995 268 6, part 1 L911 L917 2-s2.0-0028830762
9. Bulau P., Zakrzewicz D., Kitowska K., Leiper J., Gunther A., Grimminger F., Eickelberg O., Analysis of methylarginine metabolism in the cardiovascular system identifies the lung as a major source of ADMA. American Journal of Physiology-Lung Cellular and Molecular Physiology 2007 292 1 L18 L24 2-s2.0-33846219575 10.1152/ajplung.00076.2006 (Pubitemid 46103426)
10. Ahmad T., Mabalirajan U., Ghosh B., Agrawal A., Altered asymmetric dimethyl arginine metabolism in allergically inflamed mouse lungs. American Journal of Respiratory Cell and Molecular Biology 2010 42 1 3 8 2-s2.0-73949119562 10.1165/rcmb.2009-0137RC
11. Zakrzewicz D., Eickelberg O., From arginine methylation to ADMA: a novel mechanism with therapeutic potential in chronic lung diseases. BMC Pulmonary Medicine 2009 9, article 5 2-s2.0-60849089926 10.1186/1471-2466-9-5
12. Sisson J. H., Pavlik J. A., Wyatt T. A., Alcohol stimulates ciliary motility of isolated airway axonemes through a nitric oxide, cyclase, and cyclic nucleotide-dependent kinase mechanism. Alcoholism: Clinical and Experimental Research 2009 33 4 610 616 2-s2.0-63149128130 10.1111/j.1530-0277.2008.00875.x
13. Wyatt T. A., Spurzem J. R., May K., Sisson J. H., Regulation of ciliary beat frequency by both PKA and PKG in bovine airway epithelial cells. American Journal of Physiology-Lung Cellular and Molecular Physiology 1998 275 4, part 1 L827 L835 2-s2.0-0031754505
14. McCaskill M. L., Romberger D. J., Devasure J., Alcohol exposure alters mouse lung inflammation in response to inhaled dust. Nutrients 2012 4 7 695 710
15. Wyatt T. A., Sisson J. H., Allen-Gipson D. S., Co-exposure to cigarette smoke and alcohol decreases airway epithelial cell cilia beating in a protein kinase C ε -dependent manner. The American Journal of Pathology 2012 181 2 431 440 10.1016/j.ajpath.2012.04.022
16. Slager R. E., Devasure J. M., Pavlik J. A., Sisson J. H., Wyatt T. A., RACK1, a PKC targeting protein, is exclusively localized to basal airway epithelial cells. Journal of Histochemistry and Cytochemistry 2008 56 1 7 14 2-s2.0-37249066243 10.1369/jhc.7A7249.2007 (Pubitemid 350276497)
17. Sisson J. H., Stoner J. A., Ammons B. A., Wyatt T. A., All-digital image capture and whole-field analysis of ciliary beat frequency. Journal of Microscopy 2003 211, part 2 103 111 2-s2.0-0041657684 10.1046/j.1365-2818.2003. 01209.x (Pubitemid 36960544)
18. Klein E., Weigel J., Buford M. C., Holian A., Wells S. M., Asymmetric dimethylarginine potentiates lung inflammation in a mouse model of allergic asthma. American Journal of Physiology-Lung Cellular and Molecular Physiology 2010 299 6 L816 L825 2-s2.0-78649810960 10.1152/ajplung.00188.2010
19. Stout S. L., Wyatt T. A., Adams J. J., Sisson J. H., Nitric oxide-dependent cilia regulatory enzyme localization in bovine bronchial epithelial cells. Journal of Histochemistry and Cytochemistry 2007 55 5 433 442 2-s2.0-34247558990 10.1369/jhc.6A7089.2007 (Pubitemid 46668625)
20. Simet S. M., Pavlik J. A., Sisson J. H., Proteomic analysis of bovine axonemes exposed to acute alcohol: role of endothelial nitric oxide synthase and heat shock protein 90 in cilia stimulation2013. Alcoholism: Clinical and Experimental Research 2013 37 4 609 615
21. Sud N., Wells S. M., Sharma S., Wiseman D. A., Wilham J., Black S. M., Asymmetric dimethylarginine inhibits HSP90 activity in pulmonary arterial endothelial cells: role of mitochondrial dysfunction. American Journal of Physiology-Cell Physiology 2008 294 6 C1407 C1418 2-s2.0-47249137061 10.1152/ajpcell.00384.2007
22. Yildirim A. O., Bulau P., Zakrzewicz D., Kitowska K. E., Weissmann N., Grimminger F., Morty R. E., Eickelberg O., Increased protein arginine methylation in chronic hypoxia: role of protein arginine methyltransferases. American Journal of Respiratory Cell and Molecular Biology 2006 35 4 436 443 2-s2.0-33749179022 10.1165/rcmb.2006-0097OC (Pubitemid 44477644)
23. Frieling H., Leitmeier V., Haschemi-Nassab M., Kornhuber J., Rhein M., Bleich S., Hillemacher T., Reduced plasma levels of asymmetric di-methylarginine (ADMA) in patients with alcohol dependence normalize during withdrawal. European Neuropsychopharmacology 2012 22 11 836 840 2-s2.0-84859555715 10.1016/j.euroneuro.2012.03.010
24. Lluch P., Torondel B., Medina P., Segarra G., Del Olmo J. A., Serra M. A., Rodrigo J. M., Plasma concentrations of nitric oxide and asymmetric dimethylarginine in human alcoholic cirrhosis. Journal of Hepatology 2004 41 1 55 59 2-s2.0-3442882166 10.1016/j.jhep.2004.03.016 (Pubitemid 39005153)
25. D'Souza N. B., Nelson S., Summer W. R., Deaciuc I. V., Alcohol modulates alveolar macrophage tumor necrosis factor- α superoxide anion, and nitric oxide secretion in the rat. Alcoholism: Clinical and Experimental Research 1996 20 1 156 163 2-s2.0-0029923083 10.1111/j.1530-0277.1996.tb01059.x (Pubitemid 26077981)
26. Mookerjee R. P., Dalton R. N., Davies N. A., Hodges S. J., Turner C., Williams R., Jalan R., Inflammation is an important determinant of levels of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine (ADMA) in acute liver failure. Liver Transplantation 2007 13 3 400 405 2-s2.0-33947423436 10.1002/lt.21053 (Pubitemid 46444469)
27. Jiang J.-L., Wang S., Li N.-S., Zhang X.-H., Deng H.-W., Li Y.-J., The inhibitory effect of simvastatin on the ADMA-induced inflammatory reaction is mediated by MAPK pathways in endothelial cells. Biochemistry and Cell Biology 2007 85 1 66 77 2-s2.0-34249938223 10.1139/O06-146 (Pubitemid 46877389)
28. Galal O., Podlogar J., Verspohl E. J., Impact of ADMA (asymmetric dimethylarginine) on physiology with respect to diabetes mellitus and respiratory system BEAS-2B cells (human bronchial epithelial cells). Journal of Pharmacy and Pharmacology 2013 65 2 253 263 10.1111/j.2042-7158.2012.01590.x
29. Garbin U., Pasini A. F., Stranieri C., Manfro S., Boccioletti V., Cominacini L., Nebivolol reduces asymmetric dimethylarginine in endothelial cells by increasing dimethylarginine dimethylaminohydrolase 2 (DDAH2) expression and activity. Pharmacological Research 2007 56 6 515 521 2-s2.0-36248958181 10.1016/j.phrs.2007.09.015 (Pubitemid 350137774)
30. Wells S. M., Buford M. C., Migliaccio C. T., Holian A., Elevated asymmetric dimethylarginine alters lung function and induces collagen deposition in mice. American Journal of Respiratory Cell and Molecular Biology 2009 40 2 179 188 2-s2.0-59149102060 10.1165/rcmb.2008-0148OC
31. Scott J. A., North M. L., Rafii M., Huang H., Pencharz P., Subbarao P., Belik J., Grasemann H., Asymmetric dimethylarginine is increased in asthma. American Journal of Respiratory and Critical Care Medicine 2011 184 7 779 785 2-s2.0-80053411528 10.1164/rccm.201011-1810OC
32. Carraro S., Giordano G., Piacentini G., Asymmetric dimethylarginine in exhaled breath condensate and serum of children with asthma. Chest 2013 144 2 405 410 10.1378/chest.12-2379
33. Riccioni G., Bucciarelli V., Verini M., ADMA, SDMA, L-arginine and nitric oxide in allergic pediatric bronchial asthma. Journal of Biological Regulators and Homeostatic Agents 2012 26 3 561 566
34. Ahmad T., Mabalirajan U., Sharma A., Aich J., Makhija L., Ghosh B., Agrawal A., Simvastatin improves epithelial dysfunction and airway hyperresponsiveness: from asymmetric dimethyl-arginine to asthma. American Journal of Respiratory Cell and Molecular Biology 2011 44 4 531 539 2-s2.0-79953733007 10.1165/rcmb.2010-0041OC
35. Sousse L. E., Jonkam C. C., Traber D. L., Hawkins H. K., Rehberg S. W., Traber L. D., Herndon D. N., Enkhbaatar P., Pseudomonas aeruginosa is associated with increased lung cytokines and asymmetric dimethylarginine compared with methicillin-resistant staphylococcus aureus. Shock 2011 36 5 466 470 2-s2.0-80054945994 10.1097/SHK.0b013e3182336b45
36. Wu Y. H., Zhang X., Wang D. H., Role of asymmetric dimethylarginine in acute lung injury induced by cerebral ischemia/reperfusion injury in rats. Nan Fang Yi Ke Da Xue Xue Bao 2011 31 8 1289 1294