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Volumn 15, Issue 1, 2014, Pages 13-22

Raltegravir-emtricitabine-tenofovir as HIV nonoccupational post-exposure prophylaxis in men who have sex with men: Safety, tolerability and adherence

Author keywords

HIV; Post exposure prophylaxis; Raltegravir

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; 4 HYDROXYBUTYRIC ACID; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; ANTIHISTAMINIC AGENT; ATYPICAL ANTIPSYCHOTIC AGENT; BENZODIAZEPINE DERIVATIVE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BUDESONIDE; CALCIUM CHANNEL BLOCKING AGENT; CARBAMAZEPINE; CORTICOSTEROID; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; EMTRICITABINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; HYPNOTIC AGENT; ILLICIT DRUG; METHAMPHETAMINE; OPIATE DERIVATIVE; PHENYTOIN; PHOSPHODIESTERASE V INHIBITOR; PROTEINASE INHIBITOR; PROTON PUMP INHIBITOR; RALTEGRAVIR; SILDENAFIL; STAVUDINE; TENOFOVIR; VARDENAFIL;

EID: 84888879920     PISSN: 14642662     EISSN: 14681293     Source Type: Journal    
DOI: 10.1111/hiv.12075     Document Type: Article
Times cited : (45)

References (33)
  • 1
    • 25444448727 scopus 로고    scopus 로고
    • Updated U.S. Public Health Service guidelines for the management of occupational exposure to HIV and recommendations for postexposure prophylaxis
    • Panlilio AL, Cardo DM, Grohskopf LA, Heneine W, Ross CL. Updated U.S. Public Health Service guidelines for the management of occupational exposure to HIV and recommendations for postexposure prophylaxis. MMWR Morb Mortal Wkly Rep 2005; 54 (RR09): 1-17.
    • (2005) MMWR Morb Mortal Wkly Rep , vol.54 , Issue.RR09 , pp. 1-17
    • Panlilio, A.L.1    Cardo, D.M.2    Grohskopf, L.A.3    Heneine, W.4    Ross, C.L.5
  • 2
    • 13744249434 scopus 로고    scopus 로고
    • Antiretroviral postexposure prophylaxis after sexual, injection-drug use, or other nonoccupational exposure to HIV in the United States
    • Smith DK, Grohskopf LA, Black RJ etal. Antiretroviral postexposure prophylaxis after sexual, injection-drug use, or other nonoccupational exposure to HIV in the United States. MMWR Morb Mortal Wkly Rep 2005; 54 (RR02): 1-20.
    • (2005) MMWR Morb Mortal Wkly Rep , vol.54 , Issue.RR02 , pp. 1-20
    • Smith, D.K.1    Grohskopf, L.A.2    Black, R.J.3
  • 3
    • 83455162602 scopus 로고    scopus 로고
    • UK guideline for the use of post exposure prophylaxis for HIV following sexual exposure
    • on behalf of the BASHH PEPSE Guidelines Writing Group.
    • Benn P, Fisher M, Kulasegaram R, on behalf of the BASHH PEPSE Guidelines Writing Group. UK guideline for the use of post exposure prophylaxis for HIV following sexual exposure. Int J STD AIDS 2011; 22: 695-708.
    • (2011) Int J STD AIDS , vol.22 , pp. 695-708
    • Benn, P.1    Fisher, M.2    Kulasegaram, R.3
  • 4
    • 84888872245 scopus 로고    scopus 로고
    • NPEP Reference Group. Australian national guidelines for post-exposure prophylaxis after non-occupational exposure to HIV (draft). Available at (accessed 26 April).
    • NPEP Reference Group. Australian national guidelines for post-exposure prophylaxis after non-occupational exposure to HIV (draft). Available at www.ashm.org.au/ (accessed 26 April 2013).
    • (2013)
  • 5
    • 0028791836 scopus 로고
    • Prevention of SIV infection in macaques by (R)-9-(2-Phosphonylmethoxypropyl) adenine
    • Tsai C-C, Follis KE, Sabo A etal. Prevention of SIV infection in macaques by (R)-9-(2-Phosphonylmethoxypropyl) adenine. Science 1995; 270: 1197-1199.
    • (1995) Science , vol.270 , pp. 1197-1199
    • Tsai, C.-C.1    Follis, K.E.2    Sabo, A.3
  • 6
    • 0028003766 scopus 로고
    • Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group
    • Connor EM, Sperling RS, Gelber R etal. Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group. N Engl J Med 1994; 331: 1173-1180.
    • (1994) N Engl J Med , vol.331 , pp. 1173-1180
    • Connor, E.M.1    Sperling, R.S.2    Gelber, R.3
  • 7
    • 0030692781 scopus 로고    scopus 로고
    • A case-control study of HIV seroconversion in health care workers after percutaneous exposure
    • Cardo DM, Culver DH, Ciesielski CA etal. A case-control study of HIV seroconversion in health care workers after percutaneous exposure. N Engl J Med 1997; 337: 1485-1490.
    • (1997) N Engl J Med , vol.337 , pp. 1485-1490
    • Cardo, D.M.1    Culver, D.H.2    Ciesielski, C.A.3
  • 8
    • 78650549662 scopus 로고    scopus 로고
    • Preexposure chemoprophylaxis for HIV prevention in men who have sex with men
    • Grant RM, Lama JR, Anderson PL etal. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med 2010; 363: 2587-2599.
    • (2010) N Engl J Med , vol.363 , pp. 2587-2599
    • Grant, R.M.1    Lama, J.R.2    Anderson, P.L.3
  • 9
    • 80051633217 scopus 로고    scopus 로고
    • Prevention of HIV-1 infection with early antiretroviral therapy
    • Cohen MS, Chen YQ, McCauley M etal. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med 2011; 365: 493-505.
    • (2011) N Engl J Med , vol.365 , pp. 493-505
    • Cohen, M.S.1    Chen, Y.Q.2    McCauley, M.3
  • 10
    • 0033823368 scopus 로고    scopus 로고
    • Post-exposure prophylaxis with highly active antiretroviral therapy could not protect macaques from infection with SIV/HIV chimera
    • Le Grand R, Vaslin B, Larghero J etal. Post-exposure prophylaxis with highly active antiretroviral therapy could not protect macaques from infection with SIV/HIV chimera. AIDS 2000; 14: 1864-1866.
    • (2000) AIDS , vol.14 , pp. 1864-1866
    • Le Grand, R.1    Vaslin, B.2    Larghero, J.3
  • 11
    • 0032752752 scopus 로고    scopus 로고
    • Investigations of possible failures of postexposure prophylaxis following occupational exposures to human immunodeficiency virus
    • Jochimsen EM, Luo CC, Beltrami JF, Respess RA, Schable CA, Cardo DM. Investigations of possible failures of postexposure prophylaxis following occupational exposures to human immunodeficiency virus. Arch Intern Med 1999; 159: 2361-2363.
    • (1999) Arch Intern Med , vol.159 , pp. 2361-2363
    • Jochimsen, E.M.1    Luo, C.C.2    Beltrami, J.F.3    Respess, R.A.4    Schable, C.A.5    Cardo, D.M.6
  • 12
    • 27644557764 scopus 로고    scopus 로고
    • Seroconversion following nonoccupational postexposure prophylaxis against HIV
    • Roland ME, Neilands TB, Krone M etal. Seroconversion following nonoccupational postexposure prophylaxis against HIV. Clin Infect Dis 2005; 41: 1507-1513.
    • (2005) Clin Infect Dis , vol.41 , pp. 1507-1513
    • Roland, M.E.1    Neilands, T.B.2    Krone, M.3
  • 13
    • 0035873209 scopus 로고    scopus 로고
    • Tolerability of postexposure prophylaxis with zidovudine, lamivudine, and nelfinavir for human immunodeficiency virus infection
    • Rabaud C, Bevilacqua S, Beguinot I etal. Tolerability of postexposure prophylaxis with zidovudine, lamivudine, and nelfinavir for human immunodeficiency virus infection. Clin Infect Dis 2001; 32: 1494-1495.
    • (2001) Clin Infect Dis , vol.32 , pp. 1494-1495
    • Rabaud, C.1    Bevilacqua, S.2    Beguinot, I.3
  • 14
    • 12144279573 scopus 로고    scopus 로고
    • Tolerability of postexposure prophylaxis with the combination of zidovudine-lamivudine and lopinavir-ritonavir for HIV infection
    • Rabaud C, Burty C, Grandidier M etal. Tolerability of postexposure prophylaxis with the combination of zidovudine-lamivudine and lopinavir-ritonavir for HIV infection. Clin Infect Dis 2005; 40: 303-305.
    • (2005) Clin Infect Dis , vol.40 , pp. 303-305
    • Rabaud, C.1    Burty, C.2    Grandidier, M.3
  • 15
    • 58149163018 scopus 로고    scopus 로고
    • Tolerability of fosamprenavir/ritonavir associated with zidovudine-lamivudine used as postexposure prophylaxis for HIV infection
    • Burty C, Pavel S, Ghomari K etal. Tolerability of fosamprenavir/ritonavir associated with zidovudine-lamivudine used as postexposure prophylaxis for HIV infection. J Acquir Immune Defic Syndr 2008; 49: 334-336.
    • (2008) J Acquir Immune Defic Syndr , vol.49 , pp. 334-336
    • Burty, C.1    Pavel, S.2    Ghomari, K.3
  • 16
    • 77957233991 scopus 로고    scopus 로고
    • Tolerability of HIV postexposure prophylaxis with tenofovir/emtricitabine and lopinavir/ritonavir tablet formulation
    • Tosini W, Muller P, Prazuk T etal. Tolerability of HIV postexposure prophylaxis with tenofovir/emtricitabine and lopinavir/ritonavir tablet formulation. AIDS 2010; 24: 2375-2380.
    • (2010) AIDS , vol.24 , pp. 2375-2380
    • Tosini, W.1    Muller, P.2    Prazuk, T.3
  • 17
    • 84860350870 scopus 로고    scopus 로고
    • Post-exposure prophylaxis for HIV infection: a clinical trial comparing lopinavir/ritonavir versus atazanavir each with zidovudine/lamivudine
    • Diaz-Brito V, Leon A, Knobel H etal. Post-exposure prophylaxis for HIV infection: a clinical trial comparing lopinavir/ritonavir versus atazanavir each with zidovudine/lamivudine. Antivir Ther 2012; 17: 337-346.
    • (2012) Antivir Ther , vol.17 , pp. 337-346
    • Diaz-Brito, V.1    Leon, A.2    Knobel, H.3
  • 18
    • 19644386074 scopus 로고    scopus 로고
    • The use of a triple nucleoside-nucleotide regimen for nonoccupational HIV postexposure prophylaxis
    • Winston A, McAllister J, Amin J, Cooper DA, Carr A. The use of a triple nucleoside-nucleotide regimen for nonoccupational HIV postexposure prophylaxis. HIV Med 2005; 6: 191-197.
    • (2005) HIV Med , vol.6 , pp. 191-197
    • Winston, A.1    McAllister, J.2    Amin, J.3    Cooper, D.A.4    Carr, A.5
  • 19
    • 40549122636 scopus 로고    scopus 로고
    • Tenofovir DF plus lamivudine or emtricitabine for nonoccupational postexposure prophylaxis (NPEP) in a Boston community health centre
    • Mayer K, Mimiaga MJ, Cohen D etal. Tenofovir DF plus lamivudine or emtricitabine for nonoccupational postexposure prophylaxis (NPEP) in a Boston community health centre. J Acquir Immune Defic Syndr 2008; 47: 494-499.
    • (2008) J Acquir Immune Defic Syndr , vol.47 , pp. 494-499
    • Mayer, K.1    Mimiaga, M.J.2    Cohen, D.3
  • 20
    • 47949120697 scopus 로고    scopus 로고
    • Raltegravir with optimized background therapy for resistant HIV-1 infection
    • Steigbigel RT, Cooper DA, Kumar PN etal. Raltegravir with optimized background therapy for resistant HIV-1 infection. N Engl J Med 2008; 359: 339-354.
    • (2008) N Engl J Med , vol.359 , pp. 339-354
    • Steigbigel, R.T.1    Cooper, D.A.2    Kumar, P.N.3
  • 21
    • 34748860363 scopus 로고    scopus 로고
    • Rapid and durable antiretroviral effect of the HIV-1 integrase inhibitor raltegravir as part of combination therapy in treatment-naive patients with HIV-1 infection: results of a 48-Week controlled study
    • Markowitz M, Nguyen B-Y, Gotuzzo E etal. Rapid and durable antiretroviral effect of the HIV-1 integrase inhibitor raltegravir as part of combination therapy in treatment-naive patients with HIV-1 infection: results of a 48-Week controlled study. J Acquir Immune Defic Syndr 2007; 46: 125-133.
    • (2007) J Acquir Immune Defic Syndr , vol.46 , pp. 125-133
    • Markowitz, M.1    Nguyen, B.-Y.2    Gotuzzo, E.3
  • 22
    • 84865704490 scopus 로고    scopus 로고
    • Sustained efficacy and safety of raltegravir after 5 years of combination antiretroviral therapy as initial treatment of HIV-1 infection: final results of a randomized controlled phase II study (protocol 004)
    • Gotuzzo E, Markowitz M, Ratanasuwan W etal. Sustained efficacy and safety of raltegravir after 5 years of combination antiretroviral therapy as initial treatment of HIV-1 infection: final results of a randomized controlled phase II study (protocol 004). J Acquir Immune Defic Syndr 2012; 61: 73-77.
    • (2012) J Acquir Immune Defic Syndr , vol.61 , pp. 73-77
    • Gotuzzo, E.1    Markowitz, M.2    Ratanasuwan, W.3
  • 23
    • 84876412858 scopus 로고    scopus 로고
    • Skeletal muscle toxicity associated with raltegravir-based combination anti-retroviral therapy in HIV-infected adults
    • Lee FJ, Amin J, Bloch M, Pett SL, Marriott D, Carr A. Skeletal muscle toxicity associated with raltegravir-based combination anti-retroviral therapy in HIV-infected adults. J Acquir Immune Defic Syndr 2013; 62: 525-533.
    • (2013) J Acquir Immune Defic Syndr , vol.62 , pp. 525-533
    • Lee, F.J.1    Amin, J.2    Bloch, M.3    Pett, S.L.4    Marriott, D.5    Carr, A.6
  • 24
    • 84859735735 scopus 로고    scopus 로고
    • Raltegravir, Tenofovir DF and Emtricitabine for postexposure prophylaxis to prevent the sexual transmission of HIV: safety, tolerability and adherence
    • Mayer KH, Mimiaga MJ, Gelman M, Grasso C. Raltegravir, Tenofovir DF and Emtricitabine for postexposure prophylaxis to prevent the sexual transmission of HIV: safety, tolerability and adherence. J Acquir Immune Defic Syndr 2012; 59: 354-359.
    • (2012) J Acquir Immune Defic Syndr , vol.59 , pp. 354-359
    • Mayer, K.H.1    Mimiaga, M.J.2    Gelman, M.3    Grasso, C.4
  • 25
    • 84888864808 scopus 로고    scopus 로고
    • Australasian Society for HIV Medicine. HSS Guidelines for the use of antiretroviral agents in HIV-1 infected adults and adolescents (). Available at (accessed 26 April 2013).
    • Australasian Society for HIV Medicine. HSS Guidelines for the use of antiretroviral agents in HIV-1 infected adults and adolescents (2012). Available at www.ashm.org.au/ (accessed 26 April 2013).
    • (2012)
  • 26
    • 84888856448 scopus 로고    scopus 로고
    • National Institute of Allergy and Infectious Diseases, Division of AIDS. Table for grading the severity of adult and pediatric adverse events version 1.0 (clarification August 2009) (2004). Available at (accessed 31 August 2013).
    • National Institute of Allergy and Infectious Diseases, Division of AIDS. Table for grading the severity of adult and pediatric adverse events version 1.0 (clarification August 2009) (2004). Available at http://rsc.tech-res.com/safetyandpharmacovigilance/gradingtables.aspx (accessed 31 August 2013).
  • 27
    • 36349003452 scopus 로고    scopus 로고
    • Australian national guidelines for post-exposure prophylaxis after nonoccupational exposure to HIV
    • NPEP Reference Group.
    • NPEP Reference Group. Australian national guidelines for post-exposure prophylaxis after nonoccupational exposure to HIV. Sex Health 2007; 4: 277-283.
    • (2007) Sex Health , vol.4 , pp. 277-283
  • 28
    • 84888862966 scopus 로고    scopus 로고
    • New York State Department of Health AIDS Institute. HIV prophylaxis following occupational exposure. Available at (accessed 26 April).
    • New York State Department of Health AIDS Institute. HIV prophylaxis following occupational exposure. Available at www.hivguidelines.org/clinical-guidelines/post-exposure-prophylaxis/hiv-prophylaxis-following-occupational-exposure/ (accessed 26 April 2013).
    • (2013)
  • 29
    • 77955985534 scopus 로고    scopus 로고
    • Methadone, Buprenorphine, and street drugs interactions with antiretroviral medication
    • Gruber VA, McCance-Katz EF. Methadone, Buprenorphine, and street drugs interactions with antiretroviral medication. Curr HIV/AIDS Rep 2010; 7: 152-160.
    • (2010) Curr HIV/AIDS Rep , vol.7 , pp. 152-160
    • Gruber, V.A.1    McCance-Katz, E.F.2
  • 30
    • 0032576351 scopus 로고    scopus 로고
    • Fatal reaction between ritonavir and MDMA
    • Henry JA, Hill IR. Fatal reaction between ritonavir and MDMA. Lancet 1998; 28: 1751-1752.
    • (1998) Lancet , vol.28 , pp. 1751-1752
    • Henry, J.A.1    Hill, I.R.2
  • 31
    • 0033547191 scopus 로고    scopus 로고
    • Life-threatening interactions between HIV-1 protease inhibitors and the illicit drugs MDMA and gamma-hydroxybutyrate
    • Harrington RD, Woodward JA, Hooton TM, Horn JL. Life-threatening interactions between HIV-1 protease inhibitors and the illicit drugs MDMA and gamma-hydroxybutyrate. Arch Intern Med 1999; 159: 2221-2224.
    • (1999) Arch Intern Med , vol.159 , pp. 2221-2224
    • Harrington, R.D.1    Woodward, J.A.2    Hooton, T.M.3    Horn, J.L.4
  • 32
    • 0024417553 scopus 로고
    • The natural history of medication compliance in a drug trial: limitations of pill counts
    • Rudd P, Byyny RL, Zachary V etal. The natural history of medication compliance in a drug trial: limitations of pill counts. Clin Pharmacol Ther 1989; 46: 169-176.
    • (1989) Clin Pharmacol Ther , vol.46 , pp. 169-176
    • Rudd, P.1    Byyny, R.L.2    Zachary, V.3
  • 33
    • 0035873622 scopus 로고    scopus 로고
    • A comparison study of multiple measures of adherence to HIV protease inhibitors
    • Liu H, Golin CE, Miller LG etal. A comparison study of multiple measures of adherence to HIV protease inhibitors. Ann Intern Med 2001; a34: 968-977.
    • (2001) Ann Intern Med , vol.A34 , pp. 968-977
    • Liu, H.1    Golin, C.E.2    Miller, L.G.3


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