Transplantation: Autoantibodies - Epiphenomena or biological clues

Nature Reviews Nephrology

Volumn 9, Issue 12, 2013, Pages 705-706

  Halloran, Philip F ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIBODY; AUTOANTIBODY; IMMUNOGLOBULIN G; NEUTROPHIL CYTOPLASMIC ANTIBODY;

ANTIBODY MEDIATED REJECTION; ANTIBODY PRODUCTION; APOPTOSIS; B LYMPHOCYTE; CHRONIC DISEASE; CLONE; COMPLEMENT ACTIVATION; GLOMERULONEPHRITIS; GRAFT RECIPIENT; HEART GRAFT; HUMAN; KIDNEY TRANSPLANTATION; LUNG TRANSPLANTATION; MICROCIRCULATION; PATHOGENESIS; PRIORITY JOURNAL; RISK FACTOR; SHORT SURVEY; TISSUE INJURY; WEGENER GRANULOMATOSIS;

APOPTOSIS; AUTOANTIBODIES; COMPLEMENT ACTIVATION; COMPLEMENT C4B; FEMALE; GRAFT REJECTION; HUMANS; KIDNEY TRANSPLANTATION; PEPTIDE FRAGMENTS;

EID: 84888865654     PISSN: 17595061     EISSN: 1759507X     Source Type: Journal    
DOI: 10.1038/nrneph.2013.221     Document Type: Short Survey

References (10)

1. Porcheray, F. et al. Polyreactive antibodies developing amidst humoral rejection of human kidney grafts bind apoptotic cells and activate complement. Am. J. Transplant. 13, 2590-2600 (2013)
2. Irani, R. A. et al. The detrimental role of angiotensin receptor agonistic autoantibodies in intrauterine growth restriction seen in preeclampsia. J. Exp. Med. 206, 2809-2822 (2009)
3. Lv, H. et al. Impaired thymic tolerance to alpha-myosin directs autoimmunity to the heart in mice and humans. J. Clin. Invest. 121, 1561-1573 (2011)
4. Li, L. et al. Identifying compartment-specific non-HLA targets after renal transplantation by integrating transcriptome and "antibodyome" measures. Proc. Natl Acad. Sci. USA 106, 4148-4153 (2009)
5. Dragun, D. et al. Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection. N. Engl. J. Med. 352, 558-569 (2005) (Pubitemid 40204669)
6. Snyder, L. D. et al. Implications for human leukocyte antigen antibodies after lung transplantation: A 10-year experience in 441 patients. Chest 144, 226-233 (2013)
7. Halloran, P. F., Reeve, J., Pereira, A. B., Hidalgo, L. G. & Famulski, K. S. Antibody-mediated rejection, T cell-mediated rejection, and the injury-repair response: new insights from the Genome Canada studies of kidney transplant biopsies. Kidney Int. http://dx.doi.org/10.1038/ki.2013.300
8. Kobashigawa, J. et al. Report from a consensus conference on antibody-mediated rejection in heart transplantation. J. Heart Lung Transplant. 30, 252-269 (2011)
9. Hachem, R. R. et al. Antibodies to K-? 1 tubulin and collagen V are associated with chronic rejection after lung transplantation. Am. J. Transplant. 12, 2164-2171 (2012)
10. Porcheray, F. et al. B-cell immunity in the context of T-cell tolerance after combined kidney and bone marrow transplantation in humans. Am. J. Transplant. 9, 2126-2135 (2009)