Detection of synthetic cannabinoids in oral fluid using ELISA and LC-MS-MS

Journal of Analytical Toxicology

Volumn 37, Issue 8, 2013, Pages 526-533

  Rodrigues, Warren C ^a   Catbagan, Philip ^a   Rana, Sumandeep ^b   Wang, Guohong ^a   Moore, Christine ^a  

^a Immunalysis Corporation   (United States)

^b Redwood Toxicology Laboratory   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (1 NAPHTHOYL) 1 PENTYLINDOLE; AM1220; AM2201; AM2232; CANNABINOID DERIVATIVE; JWH022; JWH073; UNCLASSIFIED DRUG;

ANALYTICAL PARAMETERS; ARTICLE; CALIBRATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUID INTAKE; HUMAN; HUMAN EXPERIMENT; IMMUNOASSAY; LIQUID CHROMATOGRAPHY; NORMAL HUMAN; SALIVATION; SCREENING TEST; SPICE; STANDARD; TANDEM MASS SPECTROMETRY;

CALIBRATION; CANNABINOIDS; CHROMATOGRAPHY, LIQUID; DESIGNER DRUGS; DRUG STABILITY; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; MOLECULAR STRUCTURE; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SALIVA; SENSITIVITY AND SPECIFICITY; SUBSTANCE ABUSE DETECTION; TANDEM MASS SPECTROMETRY;

EID: 84888865214     PISSN: 01464760     EISSN: 19452403     Source Type: Journal    
DOI: 10.1093/jat/bkt067     Document Type: Article

References (18)

1. Coulter, C., Garnier, M., Moore, C. (2011) Synthetic cannabinoids in oral fluid. Journal of Analytical Toxicology, 35, 424-430.
2. Kneisel, S., Auwä rter, V., Kempf, J. (2012) Analysis of 30 synthetic cannabinoids in oral fluid using liquid chromatography-electrospray ionization tandem mass spectrometry. Drug Testing and Analysis. doi:10.1002/dta.1429.
3. Strano-Rossi, S., Anzillotti, L., Castrignanò , E., Romolo, F.S., Chiarotti, M. (2012) Ultra high performance liquid chromatography-electrospray ionization-tandem mass spectrometry screening method for direct analysis of designer drugs, 'spice' and stimulants in oral fluid. Journal of Chromatography A, 1258, 37-42.
4. Gallardo, E., Barroso, M., Queiroz, J.A. (2009) Current technologies and considerations for drug bioanalysis in oral fluid. Bioanalysis, 1, 637-667.
5. Garnier, M., Coulter, C., Moore, C. (2011) Selection of an immunoassay screening cut-off concentration for opioids in oral fluid. Journal of Analytical Toxicology, 35, 369-374.
6. Schwope, D.M., Milman, G., Huestis, M.A. (2010) Validation of an enzyme immunoassay for detection and semi-quantification of cannabinoids in oral fluid. Clinical Chemistry, 56, 1007-1014.
7. Moore, C. (2011) Oral fluid and hair in workplace drug testing programs: new technology for immunoassays. Drug Testing and Analysis, 3, 166-168.
8. Gallardo, E., Barroso, M., Queiroz, J.A. (2009) LC-MS: a powerful tool in workplace drug testing. Drug Testing and Analysis, 1, 109-115.
9. Concheiro, M., de Castro, A., Quintela, O., Cruz, A., Lopez-Rivadulla, M. (2008) Determination of illicit and medicinal drug and their metabolites in oral fluid and preserved oral fluid by liquid chromatography mass spectrometry. Analytical and Bioanalytical Chemistry, 391, 2329-2338.
10. Moore, C. (2012) Oral fluid for workplace drug testing: laboratory implementation. Drug Testing and Analysis, 4, 89-93.
11. Vogeser, M., Seger, C. (2010) Pitfalls associated with the use of liquid chromatography-tandem mass spectrometry in the clinical laboratory. Clinical Chemistry, 56, 1234-1244.
12. Allen, K.R. (2011) Screening for drugs of abuse: which matrix, oral fluid or urine. Annals of Clinical Biochemistry, 48, 531-541.
13. Tuyay, J., Coulter, C., Rodrigues, W., Moore, C. (2012) Disposition of opioids in oral fluid: importance of chromatography and mass spectral transitions in LC-MS/MS. Drug Testing and Analysis, 4, 395-401.
14. Anderson, G., Scott, M. (1991) Determination of product shelf life and activation energy for five drugs of abuse. Clinical Chemistry, 37, 398-402.
15. Emanuel, C.E., Ellison, B., Banks, C.E. (2010) Spice up your life: screening the illegal components of 'Spice' herbal products. Analytical Methods, 2, 614-616.
16. Dresen, S., Ferreiros, N., Putz, M., Westphal, F., Zimmermann, R., Auwarter, V. (2010) Monitoring of herbal mixtures potentially containing synthetic cannabinoids as psychoactive compounds. Journal of Mass Spectrometry, 45, 1186-1194.
17. Uchiyama, N., Kawamura, M., Kikura-Hanajiri, R., Goda, Y. (2012) URB-754: a new class of designer drug and 12 synthetic cannabinoids detected in illegal products. Forensic Science International. http:// dx.doi.org/10.1016/j.forsciint.2012.08.047
18. Ludger, E., Kruger, K., Lindigkeit, R., Schiebel, H.M., Beuerle, T. (2012) Synthetic cannabinoids in 'Spice-like' herbal blends: first appearance of JWH-307 and recurrence of JWH-018 on the German market. Forensic Science International, 222, 216-222.