-
1
-
-
63149168979
-
Phase i study of cediranib in combination with oxaliplatin and infusional 5-Fluorouracil in patients with advanced colorectal cancer
-
Chen E, Jonker D, Gauthier I, Maclean M, Wells J, Powers J, Seymour L (2009) Phase I study of cediranib in combination with oxaliplatin and infusional 5-fluorouracil in patients with advanced colorectal cancer. Clin Cancer Res 15: 1481-1486.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 1481-1486
-
-
Chen, E.1
Jonker, D.2
Gauthier, I.3
MacLean, M.4
Wells, J.5
Powers, J.6
Seymour, L.7
-
2
-
-
34547681379
-
Phase I clinical study of AZD2171, an oral vascular endothelial growth factor signaling inhibitor, in patients with advanced solid tumors
-
DOI 10.1200/JCO.2006.07.2066
-
Drevs J, Siegert P, Medinger M, Mross K, Strecker R, Zirrgiebel U, Harder J, Blum H, Robertson J, Jürgensmeier JM, Puchalski TA, Young H, Saunders O, Unger C (2007) Phase I clinical study of AZD2171, an oral vascular endothelial growth factor signaling inhibitor, in patients with advanced solid tumors. J Clin Oncol 25: 3045-3054. (Pubitemid 47218051)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.21
, pp. 3045-3054
-
-
Drevs, J.1
Siegert, P.2
Medinger, M.3
Mross, K.4
Strecker, R.5
Zirrgiebel, U.6
Harder, J.7
Blum, H.8
Robertson, J.9
Jurgensmeier, J.M.10
Puchalski, T.A.11
Young, H.12
Saunders, O.13
Unger, C.14
-
3
-
-
0035470889
-
Greedy function approximation: A gradient boosting machine
-
Friedman JH (2001) Greedy function approximation; a gradient boosting machine. Ann Stat 29: 1189-1232. (Pubitemid 33405972)
-
(2001)
Annals of Statistics
, vol.29
, Issue.5
, pp. 1189-1232
-
-
Friedman, J.H.1
-
4
-
-
3042769441
-
Current approaches to first-line treatment of advanced colorectal cancer
-
Goldberg RM (2004) Current approaches to first-line treatment of advanced colorectal cancer. Clin Colorectal Cancer 4: S9-S15. (Pubitemid 38854684)
-
(2004)
Clinical Colorectal Cancer
, vol.4
, Issue.SUPPL. 1
-
-
Goldberg, R.M.1
-
5
-
-
84874095390
-
Predictive impact of circulating vascular endothelial growth factor in 4 Phase III trials evaluating bevacizumab
-
Hegde PS, Jubb AM, Chen D, Li NF, Meng G, Bernaards C, Elliott R, Scherer S, Chen DS (2013) Predictive impact of circulating vascular endothelial growth factor in 4 Phase III trials evaluating bevacizumab. Clin Cancer Res 19: 929-937.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 929-937
-
-
Hegde, P.S.1
Jubb, A.M.2
Chen, D.3
Li, N.F.4
Meng, G.5
Bernaards, C.6
Elliott, R.7
Scherer, S.8
Chen, D.S.9
-
6
-
-
84867602281
-
Cediranib plus FOLFOX/CAPOX versus placebo plus FOLFOX/CAPOX in patients with previously untreated metastatic colorectal cancer: A randomized, double-Blind, phase III study (HORIZON II)
-
on behalf of the HORIZON II study group
-
Hoff PM, Hochhaus A, Pestalozzi BC, Tebbutt NC, Li J, Kim TW, Koynov KD, Kurteva G, Pintér T, Cheng Y, van Eyll B, Pike L, Fielding A, Robertson JD, Saunders MP. on behalf of the HORIZON II study group (2012) Cediranib plus FOLFOX/CAPOX versus placebo plus FOLFOX/CAPOX in patients with previously untreated metastatic colorectal cancer: a randomized, double-blind, phase III study (HORIZON II). J Clin Oncol 30: 3596-3603.
-
(2012)
J Clin Oncol
, vol.30
, pp. 3596-3603
-
-
Hoff, P.M.1
Hochhaus, A.2
Pestalozzi, B.C.3
Tebbutt, N.C.4
Li, J.5
Kim, T.W.6
Koynov, K.D.7
Kurteva, G.8
Pintér, T.9
Cheng, Y.10
Van Eyll, B.11
Pike, L.12
Fielding, A.13
Robertson, J.D.14
Saunders, M.P.15
-
7
-
-
84876417691
-
Prognostic and predictive value of VEGF, sVEGFR-2 and CEA in mCRC studies comparing cediranib, bevacizumab and chemotherapy
-
Jürgensmeier JM, Schmoll H-J, Robertson JD, Brooks L, Taboada M, Morgan SR, Wilson D, Hoff PM (2013) Prognostic and predictive value of VEGF, sVEGFR-2 and CEA in mCRC studies comparing cediranib, bevacizumab and chemotherapy. Br J Cancer 108: 1316-1323.
-
(2013)
Br J Cancer
, vol.108
, pp. 1316-1323
-
-
Jürgensmeier, J.M.1
Schmoll, H.-J.2
Robertson, J.D.3
Brooks, L.4
Taboada, M.5
Morgan, S.R.6
Wilson, D.7
Hoff, P.M.8
-
8
-
-
75749096309
-
Phase II trial of infusional fluorouracil, irinotecan, and bevacizumab for metastatic colorectal cancer: Efficacy and circulating angiogenic biomarkers associated with therapeutic resistance
-
Kopetz S, Hoff PM, Morris JS, Wolff RA, Eng C, Glover KY, Adinin R, Overman MJ, Valero V, Wen S, Lieu C, Yan S, Tran HT, Ellis LM, Abbruzzese JL, Heymach JV (2010) Phase II trial of infusional fluorouracil, irinotecan, and bevacizumab for metastatic colorectal cancer: efficacy and circulating angiogenic biomarkers associated with therapeutic resistance. J Clin Oncol 28: 453-459.
-
(2010)
J Clin Oncol
, vol.28
, pp. 453-459
-
-
Kopetz, S.1
Hoff, P.M.2
Morris, J.S.3
Wolff, R.A.4
Eng, C.5
Glover, K.Y.6
Adinin, R.7
Overman, M.J.8
Valero, V.9
Wen, S.10
Lieu, C.11
Yan, S.12
Tran, H.T.13
Ellis, L.M.14
Abbruzzese, J.L.15
Heymach, J.V.16
-
9
-
-
84888876366
-
Correlation of angiogenic biomarker signatures with clinical outcomes in metastatic colorectal cancer patients receiving capecitabine, oxaliplatin, and bevacizumab
-
Liu Y, Starr MD, Bulusu A, Pang H, Wong NS, Honeycutt W, Amara A, Hurwitz HI, Nixon AB (2013) Correlation of angiogenic biomarker signatures with clinical outcomes in metastatic colorectal cancer patients receiving capecitabine, oxaliplatin, and bevacizumab. Cancer Med 2: 234-242.
-
(2013)
Cancer Med
, vol.2
, pp. 234-242
-
-
Liu, Y.1
Starr, M.D.2
Bulusu, A.3
Pang, H.4
Wong, N.S.5
Honeycutt, W.6
Amara, A.7
Hurwitz, H.I.8
Nixon, A.B.9
-
11
-
-
42949149159
-
Bevacizumab in combination with oxaliplatin-Based chemotherapy as first-Line therapy in metastatic colorectal cancer: A randomized phase III study
-
Saltz LB, Clarke S, Diaz-Rubio E, Scheithauer W, Figer A, Wong R, Koski S, Lichinitser M, Yang TS, Rivera F, Couture F, Sirzen F, Cassidy J (2008) Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. J Clin Oncol 26: 2013-2019.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2013-2019
-
-
Saltz, L.B.1
Clarke, S.2
Diaz-Rubio, E.3
Scheithauer, W.4
Figer, A.5
Wong, R.6
Koski, S.7
Lichinitser, M.8
Yang, T.S.9
Rivera, F.10
Couture, F.11
Sirzen, F.12
Cassidy, J.13
-
12
-
-
84867115561
-
Cediranib with mFOLFOX6 versus bevacizumab with mFOLFOX6 as first-Line treatment for patients with advanced colorectal cancer: A double-Blind, randomized phase III study (HORIZON III)
-
on behalf of the HORIZON III study group
-
Schmoll H-J, Cunningham D, Sobrero A, Karapetis CS, Rougier P, Koski SL, Kocakova I, Bondarenko I, Bodoky G, Mainwaring P, Salazar R, Barker P, Mookerjee B, Robertson J, Van Cutsem E. on behalf of the HORIZON III study group (2012) Cediranib with mFOLFOX6 versus bevacizumab with mFOLFOX6 as first-line treatment for patients with advanced colorectal cancer: a double-blind, randomized phase III study (HORIZON III). J Clin Oncol 30: 3588-3595.
-
(2012)
J Clin Oncol
, vol.30
, pp. 3588-3595
-
-
Schmoll, H.-J.1
Cunningham, D.2
Sobrero, A.3
Karapetis, C.S.4
Rougier, P.5
Koski, S.L.6
Kocakova, I.7
Bondarenko, I.8
Bodoky, G.9
Mainwaring, P.10
Salazar, R.11
Barker, P.12
Mookerjee, B.13
Robertson, J.14
Van Cutsem, E.15
-
13
-
-
84864333467
-
Prognostic or predictive plasma cytokines and angiogenic factors for patients treated with pazopanib for metastatic renal-Cell cancer: A retrospective analysis of phase 2 and phase 3 trials
-
Tran HT, Liu Y, Zurita AJ, Lin Y, Baker-Neblett KL, Martin AM, Figlin RA, Hutson TE, Sternberg CN, Amado RG, Pandite LN, Heymach JV (2012) Prognostic or predictive plasma cytokines and angiogenic factors for patients treated with pazopanib for metastatic renal-cell cancer: a retrospective analysis of phase 2 and phase 3 trials. Lancet Oncol 13: 827-837.
-
(2012)
Lancet Oncol
, vol.13
, pp. 827-837
-
-
Tran, H.T.1
Liu, Y.2
Zurita, A.J.3
Lin, Y.4
Baker-Neblett, K.L.5
Martin, A.M.6
Figlin, R.A.7
Hutson, T.E.8
Sternberg, C.N.9
Amado, R.G.10
Pandite, L.N.11
Heymach, J.V.12
-
14
-
-
20144370978
-
AZD2171: A highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer
-
DOI 10.1158/0008-5472.CAN-04-4409
-
Wedge SR, Kendrew J, Hennequin LF, Valentine PJ, Barry ST, Brave SR, Smith NR, James NH, Dukes M, Curwen JO, Chester R, Jackson JA, Boffey SJ, Kilburn LL, Barnett S, Richmond GH, Wadsworth PF, Walker M, Bigley AL, Taylor ST, Cooper L, Beck S, Jürgensmeier JM, Ogilvie DJ (2005) AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer. Cancer Res 65: 4389-4400. (Pubitemid 40775678)
-
(2005)
Cancer Research
, vol.65
, Issue.10
, pp. 4389-4400
-
-
Wedge, S.R.1
Kendrew, J.2
Hennequin, L.F.3
Valentine, P.J.4
Barry, S.T.5
Brave, S.R.6
Smith, N.R.7
James, N.H.8
Dukes, M.9
Curwen, J.O.10
Chester, R.11
Jackson, J.A.12
Boffey, S.J.13
Kilburn, L.L.14
Barnett, S.15
Richmond, G.H.P.16
Wadsworth, P.F.17
Walker, M.18
Bigley, A.L.19
Taylor, S.T.20
Cooper, L.21
Beck, S.22
Jurgensmeier, J.M.23
Ogilvie, D.J.24
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