Medical image analysis and 3-d modeling to quantify changes and functional restoration in denervated muscle undergoing electrical stimulation treatment

Human-centric Computing and Information Sciences

Volumn 2, Issue 1, 2012, Pages 1-11

  Gargiulo, Paolo ^a,b   Helgason, Thordur ^a,b   Ingvarsson, Páll ^a   Mayr, Winfried ^c   Kern, Helmut ^d   Carraro, Ugo ^e  

^a LANDSPITALI UNIVERSITY HOSPITAL   (Iceland)

^b REYKJAVIK UNIVERSITY   (Iceland)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

^d WILHELMINEN HOSPITAL   (Austria)

^e UNIVERSITY OF PADOVA   (Italy)

Author keywords

Denervated Muscle; Electrical Stimulation; Image Segmentation; Muscle Fiber; Spinal Cord Injury

Indexed keywords

3D MODELING; COLLAGEN; COMPUTERIZED TOMOGRAPHY; IMAGE ANALYSIS; IMAGE RECONSTRUCTION; IMAGE SEGMENTATION; MEDICAL IMAGE PROCESSING; PATIENT TREATMENT; RESTORATION; TISSUE ENGINEERING;

ELECTRICAL STIMULATIONS; MONITORING TECHNIQUES; MUSCLE FIBER; PARAPLEGIC PATIENTS; SEGMENTATION TECHNIQUES; SPINAL CORD INJURIES (SCI); SPIRAL COMPUTED TOMOGRAPHIES; THREE DIMENSIONAL (3-D) MODELING;

MUSCLE;

EID: 84888642227     PISSN: None     EISSN: 21921962     Source Type: Journal    
DOI: 10.1186/2192-1962-2-10     Document Type: Letter

References (18)

1. Fisher AL: Of worms and women: sarcopenia and its role in disability and mortality.J Am Geriatr Soc 2004, 52:1185–1190.
2. Janssen I, Heymsfield SB, Ross R: Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability.J Am Geriatr Soc 2002, 50:889–896.
3. Kern H, Hofer C, Strohhofer M, Mayr W, Richter W, Stöhr H: Standing up with denervated muscles in humans using functional electrical stimulation.Artif Organs 1999,23(5):447–452.
4. Kern H, Hofer C, Mödlin M, Mayr W, Vindigni V, Zampieri S, Boncompagni S, Protasi F, Carraro U: Stable muscle atrophy in long-term paraplegics with complete upper motor neuron lesion from 3- to 20-year SCI.Spinal Cord 2007, 46:293–304.
5. Mayr W, Bijak M, Rafolt D, Sauermann S, Unger E, Lanmuller H: Basic design and construction of the Vienna ES implants: existing solutions and prospects for new generations of implants.Med Eng Phys 2001, 23:53–60.
6. Kern H, Hofer C, Mayr W, Carraro U: European Project RISE: Partners, protocols, demography.Basic Appl Myol 2009, 19:211–216.
7. Mödlin M, Forstner C, Hofer C, Mayr W, Richter W, Carraro U, Protasi F, Kern H: Electrical stimulation of denervated muscles: first results of a clinical study.Artif Organs 2005, 29:203–206.
8. Kern H, Carraro U, Adami N, et al.: One year of home-based Functional Electrical Stimulation (ES) in complete lower motor neuron paraplegia: recovery of tetanic contractility drives the structural improvements of denervated muscle.Neurol Res 2010, 32:26–32.
9. Bizzarini E, Zampa A, Malisan C, Pinzini C, Di Benedetto P, Kern H, Adami N, Carraro U: Epidemiology and clinical management of Conus-Cauda Syndrome and flaccid paraplegia in Friuli Venezia Giulia: Data of the Spinal Unit of Udine.Basic Appl Myol 2009, 19:163–167.
10. Boncompagni S, Kern H, Hofer C, Mayr W, Carraro U, Protasi F: Structural differentiation of skeletal muscle fibers in the absence of innervation in humans.Proc Natl Acad Sci Unit States Am 2007, 104:19339–19344.
11. Lotta S, Scelsi R, Alfonsi E, Saitta A, Nicolotti D, Epifani P, Carraro U: Morphometric and neurophysiological analysis of skeletal muscle in paraplegic patients with traumatic cord lesion.Paraplegia 1991, 29:247–252.
12. Hofer C, Forstner C, Mödlin M, Jäger H, Mayr W, Kern H: In vivo assessment of conduction velocity and refractory period of denervated muscle fibers.Artif Organs 2005,29(6):436–439.
13. Gargiulo P, Helgason T, Reynisson PJ, Helgason B, Kern H, Mayr W, Ingvarsson P, Carraro U: Monitoring of Muscle and Bone Recovery in Spinal Cord Injury Patients Treated With ES Using Three-Dimensional Imaging and Segmentation Techniques: Methodological Assessment.Artificial Organs 2011,35(3):275–281.
14. Mandl T, Meyerspeer M, Reichel M, Helmut K, Hofer C, Mayr W: Functional electrical stimulation of long-term denervated, degenerated human skeletal muscle: estimating activation using T2-parameter magnetic resonance imaging methods.Artif Organs 2008,32(8):604–608.
15. Gargiulo P, Vatnsdal B, Ingvarsson P, Knútsdóttir S, Gudmundsdóttir V, Yngvason S, Helgason T: Restoration of Muscle Volume and Shape Induced by Electrical Stimulation of Denervated Degenerated Muscles: Qualitative and Quantitative Measurement of Changes in Rectus Femoris Using Computer Tomography and Image Segmentation.Artif Organs 2008, 32:609–613.
16. Gargiulo P, Kern H, Carraro B, Vatnsdal U, Ingvarsson P, Knútsdóttir S, Gudmundsdóttir V, Yngvason S, Helgason T: Quantitative color 3-dimensional computer tomography imaging of human long-term denervated Muscle.Neurological Research 2010, 32:13–20.
17. Materialise.Product: MIMICS 2012. Available at: http://www.materialise.com.Accessed April 3, 2012.
18. Blemker SS, Delp SL: Rectus femoris and vastus intermedius fiber excursions predicted by three-dimensional muscle models.J Biomech 2006,39(8):1383–1391.