Multicenter phase II study of everolimus in patients with metastatic or recurrent bone and soft-tissue sarcomas after failure of anthracycline and ifosfamide

Investigational New Drugs

Volumn 31, Issue 6, 2013, Pages 1602-1608

  Yoo, Changhoon ^a   Lee, Jeeyun ^b   Rha, Sun Young ^c   Park, Kyong Hwa ^d   Kim, Tae Min ^e   Kim, Yu Jung ^f   Lee, Hyo Jin ^g   Lee, Kyung Hee ^h   Ahn, Jin Hee ^a  

^a University of Ulsan College of Medicine   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

^c Yonsei University College of Medicine   (South Korea)

^d College of Medicine   (South Korea)

^e Seoul National University Hospital   (South Korea)

^f Seoul National University Bundang Hospital   (South Korea)

^g Chungnam National University College of Medicine   (South Korea)

^h Young Nam University Hospital   (South Korea)

Author keywords

Everolimus; mTOR inhibitor; Sarcoma

Indexed keywords

ANTHRACYCLINE; EVEROLIMUS; IFOSFAMIDE; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR;

ADULT; AGED; ANEMIA; ANGIOSARCOMA; ANTINEOPLASTIC ACTIVITY; ARTICLE; ASTHENIA; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER RECURRENCE; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; DIARRHEA; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG RESPONSE; DRUG SAFETY; DRUG TREATMENT FAILURE; FEMALE; FOLLOW UP; HUMAN; HYPERGLYCEMIA; HYPERTRIGLYCERIDEMIA; HYPOALBUMINEMIA; MALE; METASTATIC BONE SARCOMA; METASTATIC SOFT TISSUE SARCOMA; MULTICENTER STUDY; NEUTROPENIA; OPEN STUDY; OSTEOSARCOMA; OVERALL SURVIVAL; PAIN; PHASE 2 CLINICAL TRIAL; PNEUMONIA; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; RASH; RECURRENT BONE SARCOMA; RECURRENT SOFT TISSUE SARCOMA; SOFT TISSUE SARCOMA; STOMATITIS; THROMBOCYTOPENIA; TREATMENT DURATION; VERY ELDERLY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTHRACYCLINES; ANTINEOPLASTIC AGENTS; BONE NEOPLASMS; FEMALE; HUMANS; IFOSFAMIDE; MALE; MIDDLE AGED; SARCOMA; SIROLIMUS; SOFT TISSUE NEOPLASMS; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84888642081     PISSN: 01676997     EISSN: 15730646     Source Type: Journal    
DOI: 10.1007/s10637-013-0028-7     Document Type: Article

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