Medical treatment with thiamine, coenzyme Q, vitamins e and C, and carnitine improved obstructive sleep apnea in an adult case of Leigh disease

Sleep and Breathing

Volumn 17, Issue 4, 2013, Pages 1129-1135

  Mermigkis, Charalampos ^a,b   Bouloukaki, Izolde ^a,d   Mastorodemos, Vasileios ^c   Plaitakis, Andreas ^c   Alogdianakis, Vangelis ^b   Siafakas, Nikolaos ^a   Schiza, Sophia ^a  

^a UNIVERSITY HOSPITAL OF HERAKLION   (Greece)

^b 401 GENERAL MILITARY HOSPITAL OF ATHENS   (Greece)

^c UNIVERSITY OF CRETE   (Greece)

^d UNIVERSITY OF CRETE   (Greece)

Author keywords

Adults; Leigh disease; Obstructive sleep apnea; Treatment

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; CARNITINE; LACTIC ACID; THIAMINE; UBIQUINONE; VALPROIC ACID; VITAMIN D;

ABDOMINAL RADIOGRAPHY; ABDUCENS NERVE PARALYSIS; ADULT; APNEA HYPOPNEA INDEX; AROUSAL; ARTICLE; ATAXIC GAIT; BABINSKI REFLEX; BASAL GANGLION; BODY MASS; BRAIN STEM; BULBAR PARALYSIS; CASE REPORT; CEREBELLUM CORTEX; DAYTIME SOMNOLENCE; DENTATE NUCLEUS; DIASTOLIC DYSFUNCTION; DIFFUSION WEIGHTED IMAGING; DYSARTHRIA; ENCEPHALITIS; EYE MOVEMENT; FATIGUE; FEBRILE CONVULSION; FEMALE; HEART RATE; HUMAN; HYPERVENTILATION; INFERIOR OLIVE; LEIGH DISEASE; LIMB WEAKNESS; LUMBAR PUNCTURE; MUSCLE STRENGTH; NEUROIMAGING; NEUROLOGIC EXAMINATION; NONREM SLEEP; NUCLEAR MAGNETIC RESONANCE IMAGING; NYSTAGMUS; OXIDATIVE PHOSPHORYLATION; OXYGEN DESATURATION; PARIETAL LOBE; PERIAQUEDUCTAL GRAY MATTER; POLYSOMNOGRAPHY; PONS; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REM SLEEP; RESPIRATORY ALKALOSIS; SACCADIC EYE MOVEMENT; SENSORY NERVE CONDUCTION; SLEEP DISORDERED BREATHING; SLEEP QUALITY; SOMNOLENCE; SPLENOMEGALY; SYSTOLIC DYSFUNCTION; TACHYCARDIA; TEGMENTUM; TENDON REFLEX; THALAMUS; TONIC CLONIC SEIZURE; WAKEFULNESS; BRAIN; COMBINATION DRUG THERAPY; DOSE RESPONSE; DRUG EFFECTS; MALE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY; SLEEP APNEA, OBSTRUCTIVE;

ADULT; BRAIN; CARNITINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG THERAPY, COMBINATION; HUMANS; LEIGH DISEASE; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MALE; NEUROLOGIC EXAMINATION; POLYSOMNOGRAPHY; SLEEP APNEA, OBSTRUCTIVE; THIAMINE; UBIQUINONE; VITAMIN D; VITAMIN E;

EID: 84888640260     PISSN: 15209512     EISSN: 15221709     Source Type: Journal    
DOI: 10.1007/s11325-013-0816-5     Document Type: Article

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