Molecular mechanisms of HIV type 1 prophylaxis failure revealed by single-genome sequencing

Journal of Infectious Diseases

Volumn 208, Issue 10, 2013, Pages 1598-1603

  Li, Hui ^a   Blair, Lily ^b   Chen, Yalu ^c   Learn, Gerald ^a   Pfafferott, Katja ^d   John, Mina ^d   Bhattacharya, Tanmoy ^b   Hahn, Beatrice H ^a   Mallal, Simon ^d   Shaw, George M ^a   Bar, Katharine J ^b,e  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b LOS ALAMOS NATIONAL LABORATORY   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d MURDOCH UNIVERSITY   (Australia)

^e 502D Johnson Pavilion ^*  (United States)

Author keywords

Hiv 1 transmission; Multiple virus transmission; Occupational exposure; Post exposure prophylaxis; Single genome sequencing; Virus sequestration

Indexed keywords

APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3F; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; GENOMIC DNA; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; INDINAVIR; LAMIVUDINE; VIRUS RNA; ZIDOVUDINE;

ADULT; ANTIVIRAL RESISTANCE; ANTIVIRAL SUSCEPTIBILITY; ARTICLE; AUSTRALIA; CASE REPORT; DNA EXTRACTION; DRUG TREATMENT FAILURE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE SEQUENCE; HEALTH CARE PERSONNEL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MOLECULAR MECHANICS; NEEDLESTICK INJURY; PERIPHERAL BLOOD MONONUCLEAR CELL; POST EXPOSURE PROPHYLAXIS; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TREATMENT DURATION; VIREMIA; VIRUS IDENTIFICATION; VIRUS LOAD; VIRUS REPLICATION; VIRUS TRANSMISSION; WESTERN BLOTTING;

HIV-1 TRANSMISSION; MULTIPLE VIRUS TRANSMISSION; OCCUPATIONAL EXPOSURE; POST-EXPOSURE PROPHYLAXIS; SINGLE GENOME SEQUENCING; VIRUS SEQUESTRATION;

ANTI-HIV AGENTS; DRUG RESISTANCE, VIRAL; FEMALE; GENOME, VIRAL; HIV INFECTIONS; HIV-1; HUMANS; MIDDLE AGED; MUTATION; PHYLOGENY; PREMEDICATION; RNA, VIRAL; SEQUENCE ANALYSIS, DNA; TREATMENT FAILURE;

EID: 84888609092     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jit485     Document Type: Article

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