Does augmentation or induction of labor with oxytocin increase the risk for autism?

American Journal of Obstetrics and Gynecology

Volumn 209, Issue 6, 2013, Pages 502-504

  Vintzileos, Anthony M ^a   Ananth, Cande V ^b,c  

^a WINTHROP UNIVERSITY HOSPITAL   (United States)

^b Columbia University ^*  (United States)

^c Department of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OXYTOCIN; PROSTAGLANDIN;

AMNIOTOMY; AUTISM; BALLOON CATHETER; COMMUNICATION SKILL; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; DSM-IV; EDITORIAL; HIGH RISK POPULATION; HUMAN; LABOR AUGMENTATION; LABOR INDUCTION; LABOR MANAGEMENT; NONVERBAL COMMUNICATION; PATHOGENESIS; PERVASIVE DEVELOPMENTAL DISORDER NOT OTHERWISE SPECIFIED; PRIORITY JOURNAL; SEX DIFFERENCE; SOCIAL INTERACTION; STEREOTYPY; VERBAL COMMUNICATION;

EID: 84888605835     PISSN: 00029378     EISSN: 10976868     Source Type: Journal    
DOI: 10.1016/j.ajog.2013.09.003     Document Type: Editorial

References (44)

1. American Psychiatric Association Pervasive developmental disorders Diagnostic and Statistical Manual of Mental Disorders 4th ed 2000 American Psychiatric Association Washington, DC 69 70 Text Revision (DSM-IV-TR)
2. F.R. Volkmar, P. Szatmari, and S.S. Sparrow Sex differences in pervasive developmental disorders J Autism Dev Disord 23 1993 579 591
3. Prevalence of autism spectrum disorders - Autism and Developmental Disabilities Monitoring Network, 14 sites, United States, 2008 MMWR Surveill Summ 61 2012 1 19
4. S.E. Levy, D.S. Mandell, and R.T. Schultz Autism Lancet 374 2009 1627 1638
5. S. Ozonoff, G.S. Young, and A. Carter Recurrence risk for autism spectrum disorders; a Baby Siblings Research Consortium study Pediatrics 128 2011 e488 e495
6. G.S. Moore, A.W. Kneitel, C.K. Walker, W.M. Gilbert, and G. Xing Autism risk in small- and large-for-gestational-age infants Am J Obstet Gynecol 206 2012 314.e1 314.e9
7. C.M. Hultman, P. Sparen, and S. Cnattingius Perinatal risk factors for infantile autism Epidemiology 13 2002 417 423
8. D. Bilder, J. Pinborough-Zimmerman, J. Miller, and W. McMahon Prenatal, perinatal, and neonatal factors associated with autism spectrum disorders Pediatrics 123 2009 1293 1300
9. H. Gardener, D. Spiegelman, and S.L. Buka Prenatal risk factors for autism: comprehensive meta-analysis Br J Psychiatry 195 2009 7 14
10. V. Guinchat, P. Thorsen, C. Laurent, C. Cans, N. Bodeau, and D. Cohen Pre-, peri- and neonatal risk factors for autism Acta Obstet Gynecol Scand 91 2012 287 300
11. P. Krakowiak, C.K. Walker, and A.A. Bremer Maternal metabolic conditions and risk for autism and other neurodevelopmental disorders Pediatrics 129 2012 e1121 e1128
12. K.M. Lampi, L. Lehtonen, and P.L. Tran Risk of autism spectrum disorders in low birth weight and small for gestational age infants J Pediatr 161 2012 830 836
13. P. Rodier, R.K. Miller, and R.L. Brent Does treatment of premature labor with terbutaline increase the risk of autism spectrum disorders? Am J Obstet Gynecol 204 2011 91 94
14. F.R. Witter, A.W. Zimmerman, J.P. Reichmann, and S.L. Connors In utero beta 2 adrenergic agonist exposure and adverse neurophysiologic and behavioral outcomes Am J Obstet Gynecol 201 2009 553 559
15. T.R. Insel, L. Young, and Z. Wang Central oxytocin and reproductive behaviours Rev Reprod 2 1997 28 37
16. A. Bartz, and E. Hollander The neuroscience of affiliation: forging links between basic and clinical research on neuropeptides and social behavior Horm Behav 50 2006 518 528
17. K.K. Stavropoulos, and L.J. Carver Research review: social motivation and oxytocin in autism-implications for joint attention development and intervention J Child Psychol Psychiatry 54 2013 603 618
18. M. Brune Does the oxytocin receptor (OXTR) polymorphism (rs2254298) confer "vulnerability" for psychopathology or differential susceptibility? Insights from evolution BMC Med 10 2012 38
19. R.U. Wahl Could oxytocin administration during labor contribute to autism and related behavioral disorders? A look at the literature Med Hypotheses 63 2004 456 460
20. S.K. Laughton, D.W. Branch, J. Beaver, and J. Zhang Changes in labor patterns over 50 years Am J Obstet Gynecol 206 2012 419.e1 419.e9
21. S.G. Gregory, R. Anthopolos, C.E. Osgood, C.A. Grotegut, and M.L. Miranda Association of autism with induced or augmented childbirth in North Carolina birth record 1990-1998 and education research (1997-2007) databases JAMA Pediatr 167 2013 959 966
22. L.V. Baxi, R.H. Petrie, and S.N. Caritis Induction of labor with low-dose prostaglandin F2 alpha and oxytocin Am J Obstet Gynecol 136 1980 28 31
23. P. Boemi, S. Reitano, and S. Cianci A new cervical perfusion method for induction of labor with prostaglandins Am J Obstet Gynecol 144 1982 476 479
24. I.Z. MacKenzie, S. Bradley, and M.P. Embrey A simpler approach to labor induction using lipid-based prostaglandin E2 vaginal suppository Am J Obstet Gynecol 141 1981 158 162
25. I. Nagata, K. Kato, N. Makimura, T. Uesato, K. Seki, and Y. Kikuchi Comparison of plasma oxytocin levels during spontaneous labor and labor induced by amniotomy, prostaglandin F2 alpha, and prostaglandin E2 Am J Obstet Gynecol 147 1983 259 267
26. K.F. Trofatter Jr., D. Bowers, S.A. Gall, and A.P. Killam Preinduction cervical ripening with prostaglandin E2 (Prepidil) gel Am J Obstet Gynecol 153 1985 268 271
27. P. Bernstein, N. Leyland, P. Gurland, and D. Gare Cervical ripening and labor induction with prostaglandin E2 gel: a placebo-controlled study Am J Obstet Gynecol 156 1987 336 340
28. W. Rayburn, R. Gosen, C. Ramadei, R. Woods, and J. Scott Jr. Outpatient cervical ripening with prostaglandin E2 gel in uncomplicated postdate pregnancies Am J Obstet Gynecol 158 6 Pt 1 1988 1417 1423
29. J.K. Williams, M.L. Lewis, G.R. Cohen, and W.F. O'Brien The sequential use of estradiol and prostaglandin E2 topical gels for cervical ripening in high-risk term pregnancies requiring induction of labor Am J Obstet Gynecol 158 1988 55 58
30. W.F. Rayburn Prostaglandin E2 gel for cervical ripening and induction of labor: a critical analysis Am J Obstet Gynecol 160 1989 529 534
31. C.V. Smith, W.F. Rayburn, R.E. Connor, G.R. Fredstrom, and C.B. Phillips Double-blind comparison of intravaginal prostaglandin E2 gel and "chip" for preinduction cervical ripening Am J Obstet Gynecol 163 1990 845 847
32. G.M. Jackson, H.T. Sharp, and M.W. Varner Cervical ripening before induction of labor: a randomized trial of prostaglandin E2 gel versus low-dose oxytocin Am J Obstet Gynecol 171 1994 1092 1096
33. E.F. Magann, K.G. Perry Jr., J.R. Dockery Jr., J.D. Bass, S.P. Chauhan, and J.C. Morrison Cervical ripening before medical induction of labor: a comparison of prostaglandin E2, estradiol, andoxytocin Am J Obstet Gynecol 172 1995 1702 1706
34. D.A. Wing, M.M. Jones, A. Rahall, T.M. Goodwin, and R.H. Paul A comparison of misoprostol and prostaglandin E2 gel for preinduction cervical ripening and labor induction Am J Obstet Gynecol 172 1995 1804 1810
35. D.A. Wing, A. Rahall, M.M. Jones, T.M. Goodwin, and R.H. Paul Misoprostol: an effective agent for cervical ripening and labor induction Am J Obstet Gynecol 172 1995 1811 1816
36. F.J. Chuck, and B.J. Huffaker Labor induction with intravaginal misoprostol versus intracervical prostaglandin E2 gel (Prepidil gel): randomized comparison Am J Obstet Gynecol 173 1995 1137 1142
37. J.E. Stempel, R.P. Prins, and S. Dean Preinduction cervical ripening: a randomized prospective comparison of the efficacy and safety of intravaginal and intracervical prostaglandin E2 gel Am J Obstet Gynecol 176 1997 1305 1309
38. L.A. Farah, L. Sanchez-Ramos, and C. Rosa Randomized trial of two doses of the prostaglandin E1 analog misoprostol for labor induction Am J Obstet Gynecol 177 1997 364 369
39. J.K. Chyu, and H.T. Strassner Prostaglandin E2 for cervical ripening: a randomized comparison of Cervidil versus Prepidil Am J Obstet Gynecol 177 1997 606 611
40. D.S. Gottschall, A.F. Borgida, J.J. Mihalek, F. Sauer, and J.F. Rodis A randomized clinical trial comparing misoprostol with prostaglandin E2 gel for preinduction cervical ripening Am J Obstet Gynecol 177 1997 1067 1070
41. K.G. Perry Jr., J.E. Larmon, W.L. May, L.G. Robinette, and R.W. Martin Cervical ripening: a randomized comparison between intravaginal misoprostol and an intracervical balloon catheter combined with intravaginal dinoprostone Am J Obstet Gynecol 178 1998 1333 1340
42. D.A. Wing, and R.H. Paul Induction of labor with misoprostol for premature rupture of membranes beyond thirty-six weeks' gestation Am J Obstet Gynecol 179 1998 94 99
43. Practice-relevant changes to the DSM-IV-TR. Clarification of the definition of pervasive developmental disorders not otherwise specified. Available at: http://www.psychiatry.org/practice/dsm/practice-relevant-changes- to-the-dsm-iv-tr. Accessed Aug. 28, 2013.
44. F.R. Volkmar, D. Shaffer, and M. First PDDNOS in DSM-IV J Autism Dev Disord 30 2000 74 75