Reducible polyamidoamine-magnetic iron oxide self-assembled nanoparticles for doxorubicin delivery

Biomaterials

Volumn 35, Issue 4, 2014, Pages 1240-1248

  Chen, Jun ^a,b,c,e   Shi, Min ^a   Liu, Pengmin ^a   Ko, Alex ^d   Zhong, Wen ^b   Liao, WangJun ^a   Xing, Malcolm M Q ^a,b,c  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF MANITOBA   (Canada)

^c MANITOBA INSTITUTE OF CHILD HEALTH   (Canada)

^d NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^e INSTITUTE OF HIGH ENERGY PHYSICS   (China)

Author keywords

Breast tumor; Magnetic nanoparticle; Reducible polymer; Self assembly; Theranostics

Indexed keywords

BREAST TUMOR; COHERENT ANTI-STOKES RAMAN; MAGNETIC NANO-PARTICLES; MICHAEL ADDITIONS; SELF ASSEMBLED NANOPARTICLES; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES; THERANOSTICS; TWO-PHOTON EXCITED FLUORESCENCE;

ADDITION REACTIONS; COPOLYMERS; DRUG DELIVERY; GRAFTS; MAMMALS; NANOMAGNETICS; NANOPARTICLES; POLYETHYLENE OXIDES; SELF ASSEMBLY; TUMORS;

POLYETHYLENE GLYCOLS;

COPOLYMER; DOXORUBICIN; MAGNETIC NANOPARTICLE; NANOCRYSTAL; POLYAMIDOAMINE; SUPERPARAMAGNETIC IRON OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; BREAST TUMOR; CANCER CHEMOTHERAPY; CANCER INHIBITION; CELL STRAIN MCF 7; CHEMICAL STRUCTURE; CONFOCAL LASER MICROSCOPY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; FLUORESCENCE; HEART; HISTOLOGY; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; KIDNEY; LIVER; MOUSE; NANOTECHNOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUDE MOUSE; PHOTON; POLYMERIZATION; PRIORITY JOURNAL; SYNTHESIS; THERMOGRAVIMETRY; TUMOR GROWTH; TWO PHOTON EXCITED FLUORESCENCE;

MUS;

BREAST TUMOR; MAGNETIC NANOPARTICLE; REDUCIBLE POLYMER; SELF-ASSEMBLY; THERANOSTICS;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BREAST; BREAST NEOPLASMS; CELL LINE, TUMOR; DOXORUBICIN; DRUG CARRIERS; FEMALE; HUMANS; MAGNETITE NANOPARTICLES; MICE; MICE, INBRED BALB C; MICE, NUDE; OXIDATION-REDUCTION; POLYAMINES;

EID: 84888439422     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.10.057     Document Type: Article

References (38)

1. Gupta A.K., Gupta M. Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. Biomaterials 2005, 26:3995-4021.
2. Lewinski N., Colvin V., Drezek R. Cytotoxicity of nanoparticles. Small 2008, 4:26-49.
3. Pankhurst Q.A., Connolly J., Jones S.K., Dobson J. Applications of magnetic nanoparticles in biomedicine. JPhys D - Appl Phys 2003, 36:R167-R181.
4. Sun C., Lee J.S.H., Zhang M. Magnetic nanoparticles in MR imaging and drug delivery. Adv Drug Deliver Rev 2008, 60:1252-1265.
5. Hyeon T., Lee S.S., Park J., Chung Y., Bin Na H. Synthesis of highly crystalline and monodisperse maghemite nanocrystallites without a size-selection process. JAm Chem Soc 2001, 123:12798-12801.
6. Park J., An K.J., Hwang Y.S., Park J.G., Noh H.J., Kim J.Y., et al. Ultra-large-scale syntheses of monodisperse nanocrystals. Nat Mater 2004, 3:891-895.
7. Park J., Joo J., Kwon S.G., Jang Y., Hyeon T. Synthesis of monodisperse spherical nanocrystals. Angew Chem Int Ed 2007, 46:4630-4660.
8. Park J., Lee E., Hwang N.M., Kang M.S., Kim S.C., Hwang Y., et al. One-nanometer-scale size-controlled synthesis of monodisperse magnetic iron oxide nanoparticles. Angew Chem Int Ed 2005, 44:2872-2877.
9. 4 (M=Fe, Co, Mn) nanoparticles. JAm Chem Soc 2004, 126:273-279.
10. Namiki Y., Namiki T., Yoshida H., Ishii Y., Tsubota A., Koido S., et al. Anovel magnetic crystal-lipid nanostructure for magnetically guided invivo gene delivery. Nat Nanotechnol 2009, 4:598-606.
11. Qin J., Laurent S., Jo Y.S., Roch A., Mikhaylova M., Bhujwalla Z.M., et al. Ahigh-performance magnetic resonance imagingT2 contrast agent. Adv Mater 2007, 19:1874-1878.
12. Lee P.-W., Hsu S.-H., Wang J.-J., Tsai J.-S., Lin K.-J., Wey S.-P., et al. The characteristics, biodistribution, magnetic resonance imaging and biodegradability of superparamagnetic core-shell nanoparticles. Biomaterials 2010, 31:1316-1324.
13. Qin J., Jo Y.S., Muhammed M. Coating nanocrystals with amphiphilic thermosensitive copolymers. Angew Chem Int Ed 2009, 48:7845-7849.
14. Bae Y., Fukushima S., Harada A., Kataoka K. Design of environment-sensitive supramolecular assemblies for intracellular drug delivery: polymeric micelles that are responsive to intracellular pH change. Angew Chem Inter Edit 2003, 42:4640-4643.
15. Rapoport N. Physical stimuli-responsive polymeric micelles for anti-cancer drug delivery. Prog Polym Sci 2007, 32:962-990.
16. Wang C.-H., Hsiue G.-H. Polymeric micelles with a pH-responsive structure as intracellular drug carriers. JControl Release 2005, 108:140-149.
17. Chen J., Qiu X., Ouyang J., Kong J., Zhong W., Xing M.M.Q. PH and reduction dual-sensitive copolymeric micelles for intracellular doxorubicin delivery. Biomacromolecules 2011, 12:3601-3611.
18. Lu C., Xing M.M.Q., Zhong W. Shell cross-linked and hepatocyte-targeting nanoparticles containing doxorubicin via acid-cleavable linkage. Nanomed Nanotechnol 2011, 7:80-87.
19. Chen D., Xia X., Gu H., Xu Q., Ge J., Li Y., et al. PH-responsive polymeric carrier encapsulated magnetic nanoparticles for cancer targeted imaging and delivery. JMater Chem 2011, 21:12682-12690.
20. Chen J., Ouyang J., Kong J., Zhong W., Xing M.M.Q. Photo-cross-linked and pH-sensitive biodegradable micelles for doxorubicin delivery. ACS Appl Mater Interf 2013, 5:3108-3117.
21. Chen J., Xing M.M.Q., Zhong W. Degradable micelles based on hydrolytically degradable amphiphilic graft copolymers for doxorubicin delivery. Polymer 2011, 52:933-941.
22. Chen J., Zehtabi F., Ouyang J., Kong J., Zhong W., Xing M.M.Q. Reducible self-assembled micelles for enhanced intracellular delivery of doxorubicin. JMater Chem 2012, 22:7121-7129.
23. Tian Y., Chen J., Zahtabi F., Keijzer R., Xing M.M.Q. Nanomedicine as an innovative therapeutic strategy for pediatric lung diseases. Pediatr Pulmonol 2013, 48:1098-1111.
24. Tian Y., Glogowska A., Zhong W., Klonisch T., Xing M.M.Q. Polymeric mesoporous silica nanoparticles as a pH-responsive switch to control doxorubicin intracellular delivery. JMater Chem B 2013, 1:5264-5272.
25. Hwang C., Sinskey A.J., Lodish H.F. Oxidized redox state of glutathione in the endoplasmic - reticulum. Science 1992, 257:1496-1502.
26. Jones D.P., Carlson J.L., Mody V.C., Cai J.Y., Lynn M.J., Sternberg P. Redox state of glutathione in human plasma. Free Radical Bio Med 2000, 28:625-635.
27. Arrigo A.P. Gene expression and the thiol redox state. Free Radical Bio Med 1999, 27:936-944.
28. Oupicky D., Parker A.L., Seymour L.W. Laterally stabilized complexes of DNA with linear reducible polycations: strategy for triggered intracellular activation of DNA delivery vectors. JAm Chem Soc 2002, 124:8-9.
29. Sun H.L., Guo B.N., Cheng R., Meng F.H., Liu H.Y., Zhong Z.Y. Biodegradable micelles with sheddable poly(ethylene glycol) shells for triggered intracellular release of doxorubicin. Biomaterials 2009, 30:6358-6366.
30. Sun Y., Yan X.L., Yuan T.M., Liang J., Fan Y.J., Gu Z.W., et al. Disassemblable micelles based on reduction-degradable amphiphilic graft copolymers for intracellular delivery of doxorubicin. Biomaterials 2010, 31:7124-7131.
31. Luo D., Haverstick K., Belcheva N., Han E., Saltzman W.M. Poly(ethylene glycol)-conjugated PAMAM dendrimer for biocompatible, high-efficiency DNA delivery. Macromolecules 2002, 35:3456-3462.
32. Radu D.R., Lai C.Y., Jeftinija K., Rowe E.W., Jeftinija S., Lin V.S.Y. Apolyamidoamine dendrimer-capped mesoporous silica nanosphere-based gene transfection reagent. JAm Chem Soc 2004, 126:13216-13217.
33. Sunshine J., Green J.J., Mahon K.P., Yang F., Eltoukhy A.A., Nguyen D.N., et al. Small-molecule end-groups of linear polymer determine cell-type gene-delivery efficacy. Adv Mater 2009, 21:4947-4951.
34. 2 nanoparticles with different particle sizes on a sub-200-nm scale. Small 2011, 7:3026-3031.
35. Sauer A.M., Schlossbauer A., Ruthardt N., Cauda V., Bein T., Bräuchle C. Role of endosomal escape for disulfide-based drug delivery from colloidal mesoporous silica evaluated by live-cell imaging. Nano Lett 2010, 10:3684-3691.
36. Lee C.-H., Cheng S.-H., Huang I.P., Souris J.S., Yang C.-S., Mou C.-Y., et al. Intracellular pH-responsive mesoporous silica nanoparticles for the controlled release of anticancer chemotherapeutics. Angew Chem Int Edit 2010, 49:8214-8219.
37. Suh W.H., Suh Y.-H., Stucky G.D. Multifunctional nanosystems at the interface of physical and life sciences. Nano Today 2009, 4:27-36.
38. Gao C., Izquierdo-Barba I., Nakase I., Futaki S., Ruan J., Sakamoto K., et al. Mesostructured silica based delivery system for a drug with a peptide as a cell-penetrating vector. Micropor Mesopor Mater 2009, 122:201-207.