Phlebitis in Amiodarone Administration: Incidence, Contributing Factors, and Clinical Implications

American Journal of Critical Care

Volumn 22, Issue 6, 2013, Pages 498-505

  Norton, Linda ^a   Ottoboni, Linda K ^a,c   Varady, Ann ^a,b   Yang Lu, Chia Yu ^a,c   Becker, Nancy ^a   Cotter, Theresa ^a,c   Pummer, Eileen ^a,c   Haynes, Annette ^a,c   Forsey, Lynn ^a,c   Matsuda, Kelly ^a,c   Wang, Paul ^a,b  

^a STANFORD UNIVERSITY   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIODARONE; ANTIARRHYTHMIC AGENT;

ADULT; AGED; ARTICLE; CATHETERIZATION; CHEMICALLY INDUCED DISORDER; CORONARY CARE UNIT; DOSE RESPONSE; ELECTRONIC MEDICAL RECORD; FEMALE; HUMAN; INCIDENCE; INTRAVENOUS DRUG ADMINISTRATION; MALE; METHODOLOGY; MIDDLE AGED; ORGANIZATION AND MANAGEMENT; PHLEBITIS; RETROSPECTIVE STUDY; STANDARD; STATISTICAL MODEL; STATISTICS; UNITED STATES; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; AMIODARONE; ANTI-ARRHYTHMIA AGENTS; CALIFORNIA; CARDIAC CARE FACILITIES; CATHETERIZATION, PERIPHERAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRONIC HEALTH RECORDS; FEMALE; HUMANS; INCIDENCE; INFUSIONS, INTRAVENOUS; LOGISTIC MODELS; MALE; MIDDLE AGED; PHLEBITIS; RETROSPECTIVE STUDIES;

EID: 84888400482     PISSN: 10623264     EISSN: None     Source Type: Journal    
DOI: 10.4037/ajcc2013460     Document Type: Article

References (22)

1. Slim AM, Roth JE, Duffy B, Boyd SY, Rubal BJ. The incidence of phlebitis with intravenous amiodarone at guideline dose recommendations. Mil Med. 2007;172(12):1279-1283.
2. Uslusoy E, Mete S. Predisposing factors to phlebitis in patients with peripheral intravenous catheters: a descriptive study. J Am Acad Nurse Pract. 2008;20(4):172-180.
3. Mowry JL, Hartman LS. Intravascular thrombophlebitis related to the peripheral infusion of amiodarone and vancomycin. West J Nurs Res. 2011;33(3):457-471.
4. de Fatima Suardi Martinho R, Rodrigues AB. Occurrence of phlebitis in patients on intravenous amiodarone. Einstein. 2008;6(4):459-462.
5. Kreiss Y, Sidi Y, Gur H. Efficacy and safety of intravenous amiodarone in recent-onset atrial fibrillation: experience in patients admitted to a general internal medicine department. Postgrad Med J. 1999;75:278-281.
6. Schultz AA, Gallant P. Evidence-based quality improvement project for determining appropriate discontinuation of peripheral intravenous cannulas. Evid Based Nurs. 2005;8(1):8.
7. Norton L, Ottoboni L, Varady A, et al. Phlebitis in amiodarone: incidence, contributing factors and clinical implications. Poster presented at: Heart Rhythm Society 32nd Annual Scientific Sessions; May 4-7, 2011; San Francisco, California.
8. Vassallo P, Trohman RG. Prescribing amiodarone: an evidencebased review of clinical indications. JAMA. 2007;298(11): 1312-1322.
9. Aljitawi O, Shabaneh B, Whitaker J. Bilateral upper extremity thrombophlebitis related to intravenous amiodarone: a case report. South Med J. 2005;98(8):814-816.
10. Aravanis C, Papasteriades E, Steriotis J. Acute thrombophlebitis due to the use of amiodarone. Chest. 1982;82: 515-516.
11. Showkathali R, Earley MJ, Sporton S. Amiodarone induced thrombophlebitis. Emerg Med J. 2006;23(8):660.
12. Hilleman DE, Spinler SA. Conversion of recent-onset atrial fibrillation with intravenous amiodarone: a meta-analysis of randomized controlled trials. Pharmacotherapy. 2002; 22(1):66-74.
13. Tagalakis V, Kahn SR, Libman M, Blostein M. The epidemiology of peripheral vein infusion thrombophlebitis: a critical review. Am J Med. 2002;113(2);146-151.
14. Maki DG, Ringer M. Risk factors for infusion-related phlebitis with small peripheral venous catheters: a randomized controlled trial. Ann Intern Med. 1991;114(10):845-854.
15. Yalkowsky SH, Krzyzaniak JF, Ward GH. Formulation-related problems associated with intravenous drug delivery. J Pharm Sci. 1998;87(7):787-796.
16. Schroeder HG, DeLuca PP. A study on the in vitro precipitation of poorly soluble drugs from nonaqueous vehicle in human plasma. Bull Parenter Drug Assoc. 1974;28(1):1-14
17. Ward GH, Yalkowsky SH. Studies in phlebitis, VI: dilutioninduced precipitation of amiodarone HCL. J Parenter Sci Technol. 1993;47(4):161-165.
18. Ward GH, Nolan PE Jr, Chawla M, Yalkowsky SH. Studies in phlebitis: detection and quantitation using a thermographic camera. Pharm Res. 1991;8(1):76-79.
19. Ward GH, Yalkowsky SH. Studies in phlebitis, IV: Injection rate and amiodarone-induced phlebitis. J Parenter Sci Technol. 1993;47(1):40-43.
20. Ward GH, Yalkowsky SH. Studies in phlebitis, V: hemolysis as a model for phlebitis. J Parenter Sci Technol. 1993;47(1):44-46.
21. Infusion Nurses Society. Infusion nursing standards of practice. J Infus Nurs. 2006;29(1 suppl):S1-S92.
22. Groll D, Davies B, Mac Donald J, Nelson S, Virani T. Evaluation of the psychometric properties of the phlebitis and infiltration scales for the assessment of complications of peripheral vascular access devices. J Infus Nurs. 2010; 33(6):385-390.