Hyponatremia in children with bronchiolitis admitted to the pediatric intensive care unit is associated with worse outcomes

Journal of Pediatrics

Volumn 163, Issue 6, 2013, Pages

  Luu, Ricky ^a   Dewitt, Peter E ^b   Reiter, Pamela D ^a,c   Dobyns, Emily L ^a   Kaufman, Jon ^a  

^a CHILDREN S HOSPITAL COLORADO   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; BRONCHODILATING AGENT; SALBUTAMOL; SODIUM; STEROID;

ARTICLE; BRONCHIOLITIS; CHILDHOOD DISEASE; CHRONIC DISEASE; COHORT ANALYSIS; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HOSPITAL ADMISSION; HUMAN; HYPONATREMIA; INFANT; INTENSIVE CARE UNIT; INTUBATION; MAJOR CLINICAL STUDY; MALE; MECHANICAL VENTILATOR; MEDICAL RECORD REVIEW; MORTALITY; OXYGEN CONSUMPTION; OXYGEN THERAPY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SEIZURE; SODIUM BLOOD LEVEL; TREATMENT OUTCOME;

EID: 84888330014     PISSN: 00223476     EISSN: 10976833     Source Type: Journal    
DOI: 10.1016/j.jpeds.2013.06.041     Document Type: Article

References (20)

1. G.C. Funk, G. Lindner, W. Druml, B. Metnitz, C. Schwarz, and P. Bauer Incidence and prognosis of dysnatremias present on ICU admission Intensive Care Med 36 2010 304 311
2. S. Walker, D. Mount, and G. Curhan Mortality after hospitalization with mild moderate severe hyponatremia Am J Med 122 2009 857 965
3. K. Asadollahi, N. Beeching, and G. Gill Hyponatremia as a risk factor for hospital mortality QJM 99 2006 877 880
4. S. Singhi, and K.S. Chugh hyponatremia in sick children: a marker of serious illness Indian Pediatr 31 1994 19 25
5. D.K. Shay, R.C. Holman, R.D. Newman, L.L. Liu, J.W. Stout, and L.J. Anderson Bronchiolitis-associated hospitalizations among US children, 1980-1996 JAMA 282 1999 1440 1446
6. Subcommittee on Diagnosis and Management of Bronchiolitis Diagnosis and Management of Bronchiolitis Pediatrics 118 2006 1774 1793
7. M. Holliday, A. Friedman, W. Segar, R. Chesney, and L. Finberg Acute hospital-induced hyponatremia in children: a physiologic approach J Pediatr 145 2004 584 587
8. M. Pollack, K. Patel, and U. Ruttiman PRISM III: an updated Pediatric Risk of Mortality Score Crit Care Med 24 1996 743 752
9. M.G. Semple, A. Cowell, W. Dove, J. Greensill, P.S. McNamara, and C.A. Hart Dual infection of infants by human metapneumovirus and human respiratory syncytial virus is strongly associated with severe bronchiolitis J Infect Dis 191 2005 382 386
10. R Core Team R: A language and environment for statistical computing 2012 R Foundation for Statistical Computing Vienna, Austria
11. M. Moritz, and J.C. Ayus Hospital-acquired hyponatremia - why are hypotonic parenteral fluids still being used Nature 3 2007 374 382
12. M. Seifert, S. Welak, and C. Carrol Hyponatremia is associated with increased severity of disease in critically ill children with bronchiolitis Int J Clin Med 1 2010 37 40
13. S. Hanna, S.M. Tibby, A. Durward, and I.A. Murdoch Incidence of hyponatremia and hyponatremic seizures in severe respiratory syncitial virus bronchiolitis Acta Paediatr 92 2003 430 434
14. M. Darmon, E. Diconne, B. Souweine, S. Ruckly, C. Adrie, and J.F. Timsit Prognostic consequences of borderline dysnatremia: pay attention to minimal serum sodium change Crit Care 17 2013 R12
15. D. Shay, R. Holman, G. Roosevelt, M. Clarke, and L.J. Anderson Bronchiolitis-associated mortality and estimates of respiratory syncytial virus-associated deaths among US children, 1979-1997 J Infect Dis 183 2001 16 22
16. M.A. Callahan, H.T. Do, D.W. Caplan, and K. Yoon-Flannery Economic impact of hyponatremia in hospitalized patients: a retrospective cohort study Postgrad Med 121 2009 186 191
17. M. Moritz, and J.C. Ayus Prevention of hospital acquired hyponatremia: do we have the answers Pediatrics 128 2011 980 983
18. K. Armon, A. Riordan, S. Playfor, G. MIllman, and A. Khader Hyponatremia and hypokalemia during intravenous fluid administration Arch Dis Child 93 2008 285 287
19. M. Moritz, and J.C. Ayus Prevention of hospital acquired hyponatremia: a case for using isotonic saline Pediatrics 111 2003 227 230
20. K. Choong, S. Arora, J. Cheng, F. Farrokhyar, D. Reddy, and M. Walton Hypotonic versus isotonic maintenance fluids after surgery for children: a randomized controlled trial Pediatrics 128 2011 857 866