Guidance on the dental management of patients with haemophilia and congenital bleeding disorders

British Dental Journal

Volumn 215, Issue 10, 2013, Pages 497-504

  Anderson, J A M ^a,b   Brewer, A ^a   Creagh, D ^a   Hook, S ^a   Mainwaring, J ^a   McKernan, A ^a   Yee, T T ^a   Yeung, C A ^a  

^a United Kingdom Haemophilia Centre Doctors' Organisation (UKHCDO)   (United Kingdom)

^b ROYAL INFIRMARY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR; HEMOSTATIC AGENT;

BLOOD COAGULATION DISORDERS; DENTAL PROCEDURE; EMERGENCY TREATMENT; HEALTH CARE DELIVERY; HEMOPHILIA A; HEMOSTASIS; HUMAN; PATHOPHYSIOLOGY; PRACTICE GUIDELINE; UNITED KINGDOM; WOUND CLOSURE;

BLOOD COAGULATION DISORDERS; BLOOD COAGULATION FACTORS; DENTAL CARE FOR CHRONICALLY ILL; EMERGENCY TREATMENT; GREAT BRITAIN; HEALTH SERVICES ACCESSIBILITY; HEMOPHILIA A; HEMOSTATIC TECHNIQUES; HEMOSTATICS; HUMANS; PRACTICE GUIDELINES AS TOPIC; WOUND CLOSURE TECHNIQUES;

EID: 84888320597     PISSN: 00070610     EISSN: 17417503     Source Type: Journal    
DOI: 10.1038/sj.bdj.2013.1097     Document Type: Article

References (60)

1. Hewson I D, Daly J, Hallett K B et al. Consensus statement by hospital based dentists providing dental treatment for patients with inherited bleeding disorders. Aust Dent J 2011; 56: 221-226.
2. Heiland M, Weber M, Schmelzle R. Life-threatening bleeding after dental extraction in a haemophilia A patient with inhibitors to factor VIII: a case report. J Oral Maxillofac Surg 2003; 61: 1350-1353.
3. Dougall A, Fiske J. Access to special care dentistry, part 5. Safety. Br Dent J 2008; 205: 177-190.
4. Dougall A, O'Mahoney B. Evaluation of a collaborative model of shared care designed to increase access to preventive and restorative dentistry for patients with haemophilia. Haemophilia 2010; 16 (Suppl 4): 50 (Abs no 11FP04).
5. Harrington B. Primary dental care of patients with haemophilia. Haemophilia 2000; 6 (Suppl 1): 7-12.
6. Fiske J, McGeoch R J, Savidge G, Smith M P. The treatment needs of adults with inherited bleeding disorders. J Disabil Oral Health 2002; 3: 59-61.
7. Stubbs M, Lloyd J. A protocol for the dental management of von Willebrand's disease, haemophilia A and haemophilia B. Aust Dent J 2001; 46: 37-40.
8. Vinckier F, Vermylen J. Dental extractions in haemophilia: reflection on 10 years' experience. Oral Surg Oral Med Oral Pathol 1985; 59: 6-9.
9. Kats J O, Terezhalmy G T. Dental management of the patients with haemophilia. Oral Surg Oral Med Oral Pathol 1988; 66: 139-144.
10. Gupta A, Epstein J B, Cabay R J. Bleeding disorders of importance in dental care and related patient management. J Can Dent Assoc 2007; 73: 77-83.
11. Manton S, Martin A, Bhuta B. A retrospective audit of the dental health status and treatment needs of referred haematology patients attending a UK dental hospital. Haemophilia 2010; 16 (Suppl 4): 51 (Abs no 11FP09).
12. Berry E, Hilgartner M, Mariani G, Sultan Y, Members of the Medical Advisory Board, World Federation of Haemophilia; Jones P (ed). Haemophilia: facts for health care professionals. Geneva: World Health Organization, 1996.
13. Mannucci P M, Tuddenham E G. The haemophilias -from royal genes to gene therapy. N Engl J Med 2001; 344: 1773-1779.
14. Erratum in: N Engl J Med 2001; 345: 384.
15. Bolton-Maggs P H, Pasi K J. Haemophilias A and B. Lancet 2003; 361: 1801-1809.
16. Keila S. Uncontrolled bleeding during endodontic treatment as the first symptoms for diagnosing von Willebrand's disease. Oral Surg Oral Med Oral Pathol 1990; 69: 243-261.
17. Wilde J T, Cook R J. von Willebrand disease and its management in oral and maxillofacial surgery. Br J Oral Maxillofac Surg 1998; 36: 112-118.
18. Bolton-Maggs P H B. Factor XI deficiency and its management, 3rd ed. Montréal: World Federation of Haemophilia, 2008. (Treatment of Haemophilia monograph, no 16).
19. Brewer A. Dental management of patients with inhibitors to Factor VIII or Factor IX. Montréal: World Federation of Haemophilia, 2008. (Treatment of Haemophilia monograph, no 45).
20. Leal S C. Minimum intervention in dentistry: applicability for dental care of patients with inherited bleeding disorders. Haemophilia 2010; 16 (Suppl 4): 50 (Abs no 11S02).
21. United Kingdom Haemophilia Centre Directors Organization Executive Committee. Guidelines on therapeutic products to treat haemophilia and other hereditary coagulation disorders. Haemophilia 1997; 3: 63-77.
22. Mannucci P M. Desmopressin (DDAVP) in the treatment of bleeding disorders: the first twenty years. Haemophilia 2000; 6 (Suppl 1): 60-67.
23. Erratum in: Haemophilia 2000; 6: 595.
24. Mannucci P M, Ruggeri Z M, Pareti F I, Capitanio A. 1-Deamino-8-d- arginine vasopressin: a new pharmacological approach to the management of haemophilia and von Willebrand's disease. Lancet 1977; 309: 869-872.
25. Sindet-Paedersen S. Distribution of tranexamic acid to plasma and saliva after oral administration and mouth rinsing: a pharmacokinetic study. J Clin Pharmacol 1987; 27: 1005-1008.
26. Ramström G, Sindet-Paedersen G, Hall G, Blombäck M, Alander U. Prevention of postsurgical bleeding in oral surgery using tranexamic acid without dose modification of oral anticoagulants. J Oral Maxillofac Surg 1993; 51: 1211-1216.
27. Sindet-Paedersen S, Ramström G, Bernvil S, Blombäck M. Haemostatic effect of tranexamic acid mouthwash in anticoagulant-treated patients undergoing oral surgery. N Engl J Med 1989; 320: 840-843.
28. Carter G, Goss A. Tranexamic acid mouthwash -a prospective randomized study of a 2-day regimen vs 5 day regimen to prevent postoperative bleeding in anticoagulated patients requiring dental extractions. Int J Oral Maxillofac Surg 2003; 32: 504-507.
29. Carter G, Goss A, Lloyd J, Tocchetti R. Tranexamic acid mouthwash versus autologous fibrin gluein patients taking warfarin undergoing dental extractions: a randomized prospective clinical study. J Oral Maxillofacial Surg 2003; 61: 1432-1435.
30. Blinder D, Manor Y, Martinowitz U, Taicher S, Hashomer T. Dental extractions in patients maintained on continued oral anticoagulant, comparison of local haemostatic modalities. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999; 88: 137-140.
31. Perry D J, Noakes T J, Helliwell P S. Guidelines for the management of patients on oral anticoagulants requiring dental surgery. Br Dent J 2007; 203: 389-393.
32. Forbes C D, Barr R D, Reid G et al. Tranexamic acid in control of haemorrhage after dental extraction in haemophilia and Christmas disease. Br Med J 1972; 2: 311-313.
33. Walsh P N, Rizza C R, Matthews J M et al. Epsilon-Aminocaproic acid therapy for dental extractions in haemophilia and Christmas disease: a double blind controlled trial. Br J Haemol 1971; 20: 463-475.
34. Stajčić Z. The combined local/systemic use of antifibrinolytics in haemophiliacs undergoing dental extractions. Int J Oral Surg 1985; 14: 339-345.
35. Sindet-Paedersen, Stenbjerg S. Effect of local antifibrinolytic treatment with tranexamic acid in haemophiliacs undergoing oral surgery. J Oral Maxillofac Surg 1986; 44: 703-707.
36. Lee A, Boyle C A, Savidge G F, Fiske J. Effectiveness in controlling haemorrhage after dental scaling in people with haemophilia by using tranexamic acid mouthwash. Br Dent J 2005; 198: 33-38
37. Randall C (ed). Surgical management of the primary care dental patient on warfarin [updated March 2007]. North West Medicines Information Centre, 2007. Available at: www.app.dundee.ac.uk/tuith/Static/info/warfarin.pdf (accessed 20 August 2013).
38. Ambados F. Preparing tranexamic acid 4.8% mouthwash. Aust Prescr 2003; 26: 75.
39. Adornato M C, Penna K J. Haemostatic technique. Using a splint in oral bleeding. N Y State Dent J 2001; 67: 24-25.
40. Ak G, Çaki{dotless}r O, Kazanci{dotless}oǧlu H O, Zulfikar B. The use of a new haemostatic agent: Ankaferd Blood Stopper in haemophiliacs. Haemophilia 2010; 16 (Suppl 4): 51 (Abs no 11P12).
41. Department of Health and British Association for the Study of Community Dentistry. Delivering better oral health: an evidence based toolkit for prevention, 2nd ed. London: Department of Health, 2009.
42. Scottish Dental Clinical Effectiveness Programme. Prevention and management of dental caries in children: dental clinical guidance. Dundee: Scottish Dental Clinical Effectiveness Programme, 2010.
43. Scottish Dental Clinical Effectiveness Programme. Oral health assessment and review: guidance in brief. Dundee: Scottish Dental Clinical Effectiveness Programme, 2011.
44. Axelsson P, Nyström B, Lindhe J. The long-term effect of a plaque control programme on tooth mortality, caries and periodontal disease in adults. Results after 30 years of maintenance. J Clin Periodontol 2004; 31: 749-757.
45. Brewer A, Correa M E. Guidelines for dental treatment of patients with inherited bleeding disorders. Montréal: World Federation of Haemophilia, 2006. (Treatment of Haemophilia monograph, no 40).
46. Brewer A K, Roebuck E M, Donachie M et al. The dental management of adult patients with haemophilia and other congenital bleeding disorders. Haemophilia 2003; 9: 673-677.
47. Freedman M, Dougall A, White B. An audit of a protocol for the management of patients with hereditary bleeding disorders undergoing dental treatment. J Disabil Oral Health 2009; 10: 151-155.
48. Smith G, Dougall A. To audit the success rate using 4% articaine as buccal infiltration in order to anaesthetise mandibular molars for restorative dental treatment in patients with a hereditary coagulation disorder. Haemophilia 2010; 16 (Suppl 4): 51 (Abs no 11FP11).
49. Robertson D, Nusstein J, Reader A, Beck M, McCartney M. The anaesthetic efficacy of articaine in buccal infiltration of mandibular posterior teeth. J Am Dent Assoc 2007; 138: 1104-1112.
50. Israels S, Schwetz N, Boyar R, McNicol A. Bleeding disorders: characterization, dental considerations and management. J Can Dent Assoc 2006; 72: 827.
51. Hermans C, Altisent C, Batorova A et al. Replacement therapy for invasive procedures in patients with haemophilia: literature review, European survey and recommendations. Haemophilia 2009; 15: 639-658.
52. Ramström G, Blombäck M. Tooth extractions in haemophiliacs. Int J Oral Surg 1975; 4: 1-17.
53. Baudo F, de Cataldo F, Landonio G, Muti G. Management of oral bleeding in haemophilic patients. Lancet 1988; 2: 1082.
54. Rakocz M, Mazar A, Varon D, Spierer S, Blinder D, Martinowitz U. Dental extractions in patients with bleeding disorders. The use of fibrin glue. Oral Surg Oral Med Oral Pathol 1993; 75: 280-282.
55. Waly N G. Local antifibrinolytic treatment with tranexamic acid in haemophilic children undergoing dental extractions. Egypt Dent J 1995; 41: 961-968.
56. Scottish Dental Clinical Effectiveness Programme. Drug prescribing for dentistry: dental clinical guidance, 2nd ed. Dundee: Scottish Dental Clinical Effectiveness Programme, 2011.
57. Lockhart P B, Gibson J, Pond S H, Leitch J. Dental management considerations for the patient with an acquired coagulopathy. Part 2: Coagulopathies from drugs. Br Dent J 2003; 195: 495-501.
58. Scully C, Watt-Smith P, Dios R D, Giangrande P L. Complications in HIV-infected and non HIV infected haemophiliacs and other patients after oral surgery. Int J Oral Maxillofac Surg 2002; 31: 634-640.
59. British Dental Association. Infection control. www.bda.org/dentists/ advice/ba/ie.aspx (accessed 13 November 2013).
60. Department of Health. Guidance on minimising transmission risk of CJD and vCJD. Available at: www.gov.uk/government/publications/guidance-from-the-acdp- tse-risk-management-subgroup-formerly-tse-working-group (accessed 20 August 2013).