Tyrosine kinase inhibition: A therapeutic target for the management of chronic-phase chronic myeloid leukemia

Expert Review of Anticancer Therapy

Volumn 13, Issue 12, 2013, Pages 1433-1452

  Jabbour, Elias J ^a   Cortes, Jorge E ^a   Kantarjian, Hagop M ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

Chronic myeloid leukemia; Molecular response; Suboptimal response; Tyrosine kinase inhibition

Indexed keywords

ALPHA INTERFERON; BCR ABL PROTEIN; BOSUTINIB; BUSULFAN; CYTARABINE; DASATINIB; HOMOHARRINGTONINE; HYDROXYUREA; IMATINIB; NILOTINIB; PEGINTERFERON ALPHA2B; PONATINIB; PROTEIN TYROSINE KINASE;

ASTHENIA; BLAST CELL CRISIS; BLOOD TOXICITY; BONE MARROW SUPPRESSION; CANCER PROGNOSIS; CANCER RESISTANCE; CHRONIC MYELOID LEUKEMIA; DEPRESSION; DRUG DOSE COMPARISON; DRUG DOSE ESCALATION; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG MEGADOSE; DRUG SUBSTITUTION; DRUG TOLERABILITY; DRUG WITHDRAWAL; EDEMA; EVENT FREE SURVIVAL; FATIGUE; HUMAN; LEUKEMIA RELAPSE; LEUKEMIA REMISSION; LONG TERM SURVIVAL; MINIMAL RESIDUAL DISEASE; MUSCULOSKELETAL DISEASE; NEUTROPENIA; OVERALL SURVIVAL; PATHOPHYSIOLOGY; PATIENT COMPLIANCE; PHILADELPHIA 1 CHROMOSOME; PROGRESSION FREE SURVIVAL; RASH; REVIEW; SURVIVAL RATE; THROMBOCYTOPENIA; UNSPECIFIED SIDE EFFECT;

ANTINEOPLASTIC AGENTS; BENZAMIDES; DRUG RESISTANCE, NEOPLASM; HUMANS; LEUKEMIA, MYELOID, CHRONIC-PHASE; MOLECULAR TARGETED THERAPY; PIPERAZINES; PROTEIN KINASE INHIBITORS; PROTEIN-TYROSINE KINASES; PYRIMIDINES; TREATMENT OUTCOME;

EID: 84888263504     PISSN: 14737140     EISSN: 17448328     Source Type: Journal    
DOI: 10.1586/14737140.2013.859074     Document Type: Review

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